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Kick-starting the cancer-immunity cycle by targeting CD40.
Ellmark P, Mangsbo SM, Furebring C, Tötterman TH, Norlén P. Ellmark P, et al. Oncoimmunology. 2015 Mar 16;4(7):e1011484. doi: 10.1080/2162402X.2015.1011484. eCollection 2015 Jul. Oncoimmunology. 2015. PMID: 26140231 Free PMC article.
The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation.
Kvarnhammar AM, Veitonmäki N, Hägerbrand K, Dahlman A, Smith KE, Fritzell S, von Schantz L, Thagesson M, Werchau D, Smedenfors K, Johansson M, Rosén A, Åberg I, Winnerstam M, Nyblom E, Barchan K, Furebring C, Norlén P, Ellmark P. Kvarnhammar AM, et al. Among authors: ellmark p. J Immunother Cancer. 2019 Apr 11;7(1):103. doi: 10.1186/s40425-019-0570-8. J Immunother Cancer. 2019. PMID: 30975201 Free PMC article.
36 results