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Identification and characterization of novel TRPV4 modulators.
Vincent F, Acevedo A, Nguyen MT, Dourado M, DeFalco J, Gustafson A, Spiro P, Emerling DE, Kelly MG, Duncton MA. Vincent F, et al. Among authors: emerling de. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4. doi: 10.1016/j.bbrc.2009.09.007. Epub 2009 Sep 6. Biochem Biophys Res Commun. 2009. PMID: 19737537
5-benzyloxytryptamine as an antagonist of TRPM8.
DeFalco J, Steiger D, Dourado M, Emerling D, Duncton MA. DeFalco J, et al. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7076-9. doi: 10.1016/j.bmcl.2010.09.099. Epub 2010 Sep 22. Bioorg Med Chem Lett. 2010. PMID: 20965726
TRPM8 biology and medicinal chemistry.
DeFalco J, Duncton MA, Emerling D. DeFalco J, et al. Curr Top Med Chem. 2011;11(17):2237-52. doi: 10.2174/156802611796904933. Curr Top Med Chem. 2011. PMID: 21671871 Review.
Identification of orally-bioavailable antagonists of the TRPV4 ion-channel.
Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, Liu L, Dourado M, Chi C, Yip V, DeFalco J, Gustafson A, Emerling DE, Kelly MG, Kincaid J, Vincent F, Duncton MA. Wei ZL, et al. Among authors: emerling de. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. doi: 10.1016/j.bmcl.2015.06.098. Epub 2015 Jul 6. Bioorg Med Chem Lett. 2015. PMID: 26235950
Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens.
DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, Williamson KS, Chen X, Carroll SM, Espiritu Santo G, Haaser N, Nguyen N, Giladi E, Minor D, Tan YC, Sokolove JB, Steinman L, Serafini TA, Cavet G, Greenberg NM, Glanville J, Volkmuth W, Emerling DE, Robinson WH. DeFalco J, et al. Among authors: emerling de. Clin Immunol. 2018 Feb;187:37-45. doi: 10.1016/j.clim.2017.10.002. Epub 2017 Oct 12. Clin Immunol. 2018. PMID: 29031828 Free article.
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101.
Scholz A, DeFalco J, Leung Y, Aydin IT, Czupalla CJ, Cao W, Santos D, Vad N, Lippow SM, Baia G, Harbell M, Sapugay J, Zhang D, Wu DC, Wechsler E, Ye AZ, Wu JW, Peng X, Vivian J, Kaplan H, Collins R, Nguyen N, Whidden M, Kim D, Millward C, Benjamin J, Greenberg NM, Serafini TA, Emerling DE, Steinman L, Robinson WH, Manning-Bog A. Scholz A, et al. Among authors: emerling de. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2123483119. doi: 10.1073/pnas.2123483119. Epub 2022 May 4. Proc Natl Acad Sci U S A. 2022. PMID: 35507878 Free PMC article.
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