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Page 1
Targeting mitophagy in Parkinson's disease.
J Biol Chem. 2021 Jan-Jun;296:100209. doi: 10.1074/jbc.REV120.014294. Epub 2020 Dec 24.
J Biol Chem. 2021.
PMID: 33372898
Free PMC article.
Review.
Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches.
Tsefou E, Walker AS, Clark EH, Hicks AR, Luft C, Takeda K, Watanabe T, Ramazio B, Staddon JM, Briston T, Ketteler R.
Tsefou E, et al. Among authors: clark eh.
Biochem J. 2021 Dec 10;478(23):4099-4118. doi: 10.1042/BCJ20210508.
Biochem J. 2021.
PMID: 34704599
Free PMC article.
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High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy.
Tufi R, Clark EH, Hoshikawa T, Tsagkaraki C, Stanley J, Takeda K, Staddon JM, Briston T.
Tufi R, et al. Among authors: clark eh.
SLAS Discov. 2023 Apr;28(3):73-87. doi: 10.1016/j.slasd.2022.12.004. Epub 2023 Jan 4.
SLAS Discov. 2023.
PMID: 36608804
Free article.
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Ethyl-for-methyl substitution enhances the subtype specificity of mecamylamine analogues.
Mangan D, McNabola N, Clark EH, Bermudez I, Wonnacott S, Southern JM.
Mangan D, et al. Among authors: clark eh.
Org Biomol Chem. 2019 Nov 27;17(46):9892-9905. doi: 10.1039/c9ob01993f.
Org Biomol Chem. 2019.
PMID: 31713564
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A new synthesis and preliminary evaluation of some analogues of mecamylamine - a compound with anti-addiction properties.
Mangan D, McNabola N, Clark EH, Bermudez I, Wonnacott S, Southern JM.
Mangan D, et al. Among authors: clark eh.
Org Biomol Chem. 2016 Nov 22;14(46):10787-10798. doi: 10.1039/c6ob01974a.
Org Biomol Chem. 2016.
PMID: 27812593
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