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A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.
Egerod KL, Engelstoft MS, Grunddal KV, Nøhr MK, Secher A, Sakata I, Pedersen J, Windeløv JA, Füchtbauer EM, Olsen J, Sundler F, Christensen JP, Wierup N, Olsen JV, Holst JJ, Zigman JM, Poulsen SS, Schwartz TW. Egerod KL, et al. Among authors: engelstoft ms. Endocrinology. 2012 Dec;153(12):5782-95. doi: 10.1210/en.2012-1595. Epub 2012 Oct 12. Endocrinology. 2012. PMID: 23064014 Free PMC article.
Unique interaction pattern for a functionally biased ghrelin receptor agonist.
Sivertsen B, Lang M, Frimurer TM, Holliday ND, Bach A, Els S, Engelstoft MS, Petersen PS, Madsen AN, Schwartz TW, Beck-Sickinger AG, Holst B. Sivertsen B, et al. Among authors: engelstoft ms. J Biol Chem. 2011 Jun 10;286(23):20845-60. doi: 10.1074/jbc.M110.173237. Epub 2011 Mar 14. J Biol Chem. 2011. PMID: 21402696 Free PMC article.
GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes.
Nøhr MK, Pedersen MH, Gille A, Egerod KL, Engelstoft MS, Husted AS, Sichlau RM, Grunddal KV, Poulsen SS, Han S, Jones RM, Offermanns S, Schwartz TW. Nøhr MK, et al. Among authors: engelstoft ms. Endocrinology. 2013 Oct;154(10):3552-64. doi: 10.1210/en.2013-1142. Epub 2013 Jul 24. Endocrinology. 2013. PMID: 23885020
Enteroendocrine cell types revisited.
Engelstoft MS, Egerod KL, Lund ML, Schwartz TW. Engelstoft MS, et al. Curr Opin Pharmacol. 2013 Dec;13(6):912-21. doi: 10.1016/j.coph.2013.09.018. Epub 2013 Oct 17. Curr Opin Pharmacol. 2013. PMID: 24140256 Review.
Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.
Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, Tang C, Ahmed K, Offermanns S, Egerod KL, Zigman JM, Schwartz TW. Engelstoft MS, et al. Mol Metab. 2013 Sep 4;2(4):376-92. doi: 10.1016/j.molmet.2013.08.006. eCollection 2013. Mol Metab. 2013. PMID: 24327954 Free PMC article.
The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo.
Panaro BL, Tough IR, Engelstoft MS, Matthews RT, Digby GJ, Møller CL, Svendsen B, Gribble F, Reimann F, Holst JJ, Holst B, Schwartz TW, Cox HM, Cone RD. Panaro BL, et al. Among authors: engelstoft ms. Cell Metab. 2014 Dec 2;20(6):1018-29. doi: 10.1016/j.cmet.2014.10.004. Epub 2014 Nov 20. Cell Metab. 2014. PMID: 25453189 Free PMC article.
GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo.
Hauge M, Vestmar MA, Husted AS, Ekberg JP, Wright MJ, Di Salvo J, Weinglass AB, Engelstoft MS, Madsen AN, Lückmann M, Miller MW, Trujillo ME, Frimurer TM, Holst B, Howard AD, Schwartz TW. Hauge M, et al. Among authors: engelstoft ms. Mol Metab. 2014 Oct 24;4(1):3-14. doi: 10.1016/j.molmet.2014.10.002. eCollection 2015 Jan. Mol Metab. 2014. PMID: 25685685 Free PMC article.
30 results