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Expression of hPMCA4b, the major form of the plasma membrane calcium pump in megakaryoblastoid cells is greatly reduced in mature human platelets.
Pászty K, Kovács T, Lacabaratz-Porret C, Papp B, Enouf J, Filoteo AG, Penniston JT, Enyedi A. Pászty K, et al. Among authors: enyedi a. Cell Calcium. 1998 Aug;24(2):129-35. doi: 10.1016/s0143-4160(98)90080-x. Cell Calcium. 1998. PMID: 9803313
Antibodies 5F10 and JA3 (raised against the erythrocyte Ca2+ pump) were used to identify hPMCA4b as the major form of the plasma membrane Ca2+ pump in human platelets and in three human megakaryoblastoid cell lines, MEG 01, DAMI and CHRF 288-11. 5F10 was used because it has been …
Antibodies 5F10 and JA3 (raised against the erythrocyte Ca2+ pump) were used to identify hPMCA4b as the major form of the plasma membrane Ca …
Asp1080 upstream of the calmodulin-binding domain is critical for autoinhibition of hPMCA4b.
Pászty K, Penheiter AR, Verma AK, Padányi R, Filoteo AG, Penniston JT, Enyedi A. Pászty K, et al. Among authors: enyedi a. J Biol Chem. 2002 Sep 27;277(39):36146-51. doi: 10.1074/jbc.M205457200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145294 Free article.
Caspase-3 cuts immediately after this residue and activates the pump by removing the inhibitory region (Paszty, K., Verma, A. K., Padanyi, R., Filoteo, A. G., Penniston, J. T., and Enyedi, A. (2002) J. ...Site-specific mutation of Asp(1080) to Asn, Ala …
Caspase-3 cuts immediately after this residue and activates the pump by removing the inhibitory region (Paszty, K., Verma, A. K., Pad …
The caspase-3 cleavage product of the plasma membrane Ca2+-ATPase 4b is activated and appropriately targeted.
Pászty K, Antalffy G, Penheiter AR, Homolya L, Padányi R, Iliás A, Filoteo AG, Penniston JT, Enyedi A. Pászty K, et al. Among authors: enyedi a. Biochem J. 2005 Nov 1;391(Pt 3):687-92. doi: 10.1042/BJ20051012. Biochem J. 2005. PMID: 16080782 Free PMC article.
The calmodulin-activated transporter hPMCA4 (human plasma membrane Ca2+-ATPase isoform 4) is a target for cleavage by caspase-3 during apoptosis. We have demonstrated that caspase-3 generates a 120 kDa fragment of this pump which lacks the complete autoinhibitory se …
The calmodulin-activated transporter hPMCA4 (human plasma membrane Ca2+-ATPase isoform 4) is a target for cleavage by caspase-3 durin …
Cleavage of the plasma membrane Ca+ATPase during apoptosis.
Pászty K, Antalffy G, Hegedüs L, Padányi R, Penheiter AR, Filoteo AG, Penniston JT, Enyedi A. Pászty K, et al. Among authors: enyedi a. Ann N Y Acad Sci. 2007 Mar;1099:440-50. doi: 10.1196/annals.1387.003. Ann N Y Acad Sci. 2007. PMID: 17446484
123 results