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The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.
Ciuffreda L, Di Sanza C, Cesta Incani U, Eramo A, Desideri M, Biagioni F, Passeri D, Falcone I, Sette G, Bergamo P, Anichini A, Sabapathy K, McCubrey JA, Ricciardi MR, Tafuri A, Blandino G, Orlandi A, De Maria R, Cognetti F, Del Bufalo D, Milella M. Ciuffreda L, et al. Among authors: eramo a. J Mol Med (Berl). 2012 Jun;90(6):667-79. doi: 10.1007/s00109-011-0844-1. Epub 2012 Jan 4. J Mol Med (Berl). 2012. PMID: 22215152
Caspase activation without death.
Zeuner A, Eramo A, Peschle C, De Maria R. Zeuner A, et al. Among authors: eramo a. Cell Death Differ. 1999 Nov;6(11):1075-80. doi: 10.1038/sj.cdd.4400596. Cell Death Differ. 1999. PMID: 10578176 Review.
Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts.
Sette G, Fecchi K, Salvati V, Lotti F, Pilozzi E, Duranti E, Biffoni M, Pagliuca A, Martinetti D, Memeo L, Milella M, De Maria R, Eramo A. Sette G, et al. Among authors: eramo a. J Exp Clin Cancer Res. 2013 Nov 16;32(1):91. doi: 10.1186/1756-9966-32-91. J Exp Clin Cancer Res. 2013. PMID: 24238212 Free PMC article.
131 results