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Human prostate epithelial cells and prostate-derived stem cells malignantly transformed in vitro with sodium arsenite show impaired Toll like receptor -3 (TLR3)-associated anti-tumor pathway.
Alvarado-Morales I, Olivares-Illana V, Arenas-Huertero C, Reynaga-Hernández E, Layseca-Espinosa E, Tokar EJ, Escudero-Lourdes C. Alvarado-Morales I, et al. Among authors: escudero lourdes c. Toxicol Lett. 2021 Oct 10;350:185-193. doi: 10.1016/j.toxlet.2021.07.013. Epub 2021 Jul 23. Toxicol Lett. 2021. PMID: 34303791 Free PMC article.
The tumor suppressor phosphatase and tensin homolog protein (PTEN) is negatively regulated by NF-κb p50 homodimers and involves histone 3 methylation/deacetylation in UROtsa cells chronically exposed to monomethylarsonous acid.
Oliva-González C, Uresti-Rivera EE, Galicia-Cruz OG, Jasso-Robles FI, Gandolfi AJ, Escudero-Lourdes C. Oliva-González C, et al. Toxicol Lett. 2017 Oct 5;280:92-98. doi: 10.1016/j.toxlet.2017.08.013. Epub 2017 Aug 18. Toxicol Lett. 2017. PMID: 28823542
Association of glutathione S-transferase Ω 1-1 polymorphisms (A140D and E208K) with the expression of interleukin-8 (IL-8), transforming growth factor beta (TGF-β), and apoptotic protease-activating factor 1 (Apaf-1) in humans chronically exposed to arsenic in drinking water.
Escobar-García DM, Del Razo LM, Sanchez-Peña LC, Mandeville PB, Lopez-Campos C, Escudero-Lourdes C. Escobar-García DM, et al. Arch Toxicol. 2012 Jun;86(6):857-68. doi: 10.1007/s00204-012-0802-x. Arch Toxicol. 2012. PMID: 22293942
Low level exposure to monomethyl arsonous acid-induced the over-production of inflammation-related cytokines and the activation of cell signals associated with tumor progression in a urothelial cell model.
Escudero-Lourdes C, Medeiros MK, Cárdenas-González MC, Wnek SM, Gandolfi JA. Escudero-Lourdes C, et al. Toxicol Appl Pharmacol. 2010 Apr 15;244(2):162-73. doi: 10.1016/j.taap.2009.12.029. Epub 2010 Jan 4. Toxicol Appl Pharmacol. 2010. PMID: 20045430 Free PMC article.
23 results