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The following term was not found in PubMed: eriosphaera
Page 1
Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR-Driven Lung Cancer.
Huang M, Xiong D, Pan J, Zhang Q, Sei S, Shoemaker RH, Lubet RA, Montuenga LM, Wang Y, Slusher BS, You M. Huang M, et al. Adv Sci (Weinh). 2022 Sep;9(26):e2105885. doi: 10.1002/advs.202105885. Epub 2022 Jul 21. Adv Sci (Weinh). 2022. PMID: 35861366 Free PMC article.
Lung tumor development is significantly suppressed when treatment with JHU083 is combined with an EGFR peptide vaccine (EVax) than either single treatment. Flow cytometry and single-cell RNA sequencing of the lung tumors reveal that JHU083 increases CD8(+) T cell and CD4(+ …
Lung tumor development is significantly suppressed when treatment with JHU083 is combined with an EGFR peptide vaccine (EVax) than ei …
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models.
Conforti A, Marra E, Palombo F, Roscilli G, Ravà M, Fumagalli V, Muzi A, Maffei M, Luberto L, Lione L, Salvatori E, Compagnone M, Pinto E, Pavoni E, Bucci F, Vitagliano G, Stoppoloni D, Pacello ML, Cappelletti M, Ferrara FF, D'Acunto E, Chiarini V, Arriga R, Nyska A, Di Lucia P, Marotta D, Bono E, Giustini L, Sala E, Perucchini C, Paterson J, Ryan KA, Challis AR, Matusali G, Colavita F, Caselli G, Criscuolo E, Clementi N, Mancini N, Groß R, Seidel A, Wettstein L, Münch J, Donnici L, Conti M, De Francesco R, Kuka M, Ciliberto G, Castilletti C, Capobianchi MR, Ippolito G, Guidotti LG, Rovati L, Iannacone M, Aurisicchio L. Conforti A, et al. Mol Ther. 2022 Jan 5;30(1):311-326. doi: 10.1016/j.ymthe.2021.09.011. Epub 2021 Sep 20. Mol Ther. 2022. PMID: 34547465 Free PMC article.
Upon challenge with SARS-CoV-2, immunized K18-hACE2 transgenic mice showed reduced weight loss, improved pulmonary function, and lower viral replication in the lungs and brain. COVID-eVax conferred significant protection to ferrets upon SARS-CoV-2 challenge. In summary, th …
Upon challenge with SARS-CoV-2, immunized K18-hACE2 transgenic mice showed reduced weight loss, improved pulmonary function, and lower viral …
Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma.
Impellizeri JA, Gavazza A, Greissworth E, Crispo A, Montella M, Ciliberto G, Lubas G, Aurisicchio L. Impellizeri JA, et al. J Transl Med. 2018 Dec 11;16(1):349. doi: 10.1186/s12967-018-1738-6. J Transl Med. 2018. PMID: 30537967 Free PMC article.
BACKGROUND: we have recently shown that Tel-eVax, a genetic vaccine targeting dog telomerase (dTERT) and based on Adenovirus (Ad)/DNA Electro-Gene-Transfer (DNA-EGT) technology can induce strong immune response and increase overall survival (OS) of dogs affected by multice …
BACKGROUND: we have recently shown that Tel-eVax, a genetic vaccine targeting dog telomerase (dTERT) and based on Adenovirus (Ad)/DNA …
Toxicity and Local Tolerance of COVID- eVax, a Plasmid DNA Vaccine for SARS-CoV-2, Delivered by Electroporation.
Ramot Y, Caselli G, Aurisicchio L, Andreini I, Marra E, Luberto L, Stoppoloni D, Pacello ML, Monetini L, Nyska A. Ramot Y, et al. Toxicol Pathol. 2021 Oct;49(7):1255-1268. doi: 10.1177/01926233211042263. Epub 2021 Sep 8. Toxicol Pathol. 2021. PMID: 34493107
The aim of this study was to assess the systemic toxicity and local tolerance of COVID-eVax delivered intramuscularly followed by EP in Sprague Dawley (SD) rats. ...In conclusion, the intramuscular EP-assisted DNA vaccine, COVID-eVax showed an excellent safety profi …
The aim of this study was to assess the systemic toxicity and local tolerance of COVID-eVax delivered intramuscularly followed by EP …
Immunogenicity of COVID-eVax Delivered by Electroporation Is Moderately Impacted by Temperature and Molecular Isoforms.
D'Alessio F, Lione L, Salvatori E, Bucci F, Muzi A, Roscilli G, Compagnone M, Pinto E, Battistuzzi G, Conforti A, Aurisicchio L, Palombo F. D'Alessio F, et al. Vaccines (Basel). 2023 Mar 16;11(3):678. doi: 10.3390/vaccines11030678. Vaccines (Basel). 2023. PMID: 36992261 Free PMC article.
In this study, we challenged this concept by characterizing the immunological response induced by a plasmid DNA vaccine delivered using electroporation. As a model, we used COVID-eVax, a plasmid DNA-based vaccine that targets the receptor binding domain (RBD) of the SARS-C …
In this study, we challenged this concept by characterizing the immunological response induced by a plasmid DNA vaccine delivered using elec …
A first-in-human trial on the safety and immunogenicity of COVID-eVax, a cellular response-skewed DNA vaccine against COVID-19.
Aurisicchio L, Brambilla N, Cazzaniga ME, Bonfanti P, Milleri S, Ascierto PA, Capici S, Vitalini C, Girolami F, Giacovelli G, Caselli G, Visintin M, Fanti F, Ghirri M, Conforti A, Compagnone M, Lione L, Salvatori E, Pinto E, Muzi A, Marra E, Palombo F, Roscilli G, Manenti A, Montomoli E, Cadossi M, Rovati LC. Aurisicchio L, et al. Mol Ther. 2023 Mar 1;31(3):788-800. doi: 10.1016/j.ymthe.2022.12.017. Epub 2022 Dec 27. Mol Ther. 2023. PMID: 36575794 Free PMC article. Clinical Trial.
Here we report the findings from the phase 1, first-in-human, dose-escalation study of COVID-eVax, a DNA vaccine encoding the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. ...All participants completed the primary safety and immunogenicity assessments afte …
Here we report the findings from the phase 1, first-in-human, dose-escalation study of COVID-eVax, a DNA vaccine encoding the recepto …
Flavonoids, cytotoxic, antioxidant and antibacterial activities of Evax pygmaea.
Khalfallah A, Berrehal D, Bensouici C, Kabouche A, Semra Z, Voutquenne-Nazabadioko L, Alabdul Magid A, Kabouche Z. Khalfallah A, et al. Pharm Biol. 2017 Dec;55(1):2292-2296. doi: 10.1080/13880209.2017.1405997. Pharm Biol. 2017. PMID: 29191075 Free PMC article.
CONTEXT: Phytochemical study and biological potential of Evax pygmaea (L.) Brot. (Asteraceae) are reported for the first time. OBJECTIVE: To identify the secondary metabolites of Evax pygmaea and to determine its antioxidant, antibacterial and cytotoxic activities. …
CONTEXT: Phytochemical study and biological potential of Evax pygmaea (L.) Brot. (Asteraceae) are reported for the first time. OBJECT …
DNA-Vaccine-Induced Immune Response Correlates with Lower Viral SARS-CoV-2 Titers in a Ferret Model.
Compagnone M, Pinto E, Salvatori E, Lione L, Conforti A, Marchese S, Ravà M, Ryan K, Hall Y, Rayner E, Salguero FJ, Paterson J, Iannacone M, De Francesco R, Aurisicchio L, Palombo F. Compagnone M, et al. Vaccines (Basel). 2022 Jul 25;10(8):1178. doi: 10.3390/vaccines10081178. Vaccines (Basel). 2022. PMID: 35893826 Free PMC article.
To further explore alternative vaccination platforms, we developed COVID-eVax-a genetic vaccine based on plasmid DNA encoding the RBD domain of the SARS-CoV-2 spike protein. Here, we describe the correlation between immune responses and the evolution of viral infection in …
To further explore alternative vaccination platforms, we developed COVID-eVax-a genetic vaccine based on plasmid DNA encoding the RBD …
The Prospects of an Active Vaccine Against Asthma Targeting IL-5.
Bachmann MF, El-Turabi A, Fettelschoss-Gabriel A, Vogel M. Bachmann MF, et al. Front Microbiol. 2018 Oct 24;9:2522. doi: 10.3389/fmicb.2018.02522. eCollection 2018. Front Microbiol. 2018. PMID: 30405579 Free PMC article. Review.
26 results