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SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation.
Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2019152118. doi: 10.1073/pnas.2019152118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33597301
Free PMC article.
Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis.
Li K, Ji X, Seeley R, Lee WC, Shi Y, Song F, Liao X, Song C, Huang X, Rux D, Cao J, Luo X, Anderson SM, Huang W, Long F.
Li K, et al.
FASEB J. 2022 Jun;36(6):e22377. doi: 10.1096/fj.202200485R.
FASEB J. 2022.
PMID: 35608871
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Joints in the appendicular skeleton: Developmental mechanisms and evolutionary influences.
Rux D, Decker RS, Koyama E, Pacifici M.
Rux D, et al.
Curr Top Dev Biol. 2019;133:119-151. doi: 10.1016/bs.ctdb.2018.11.002. Epub 2018 Dec 10.
Curr Top Dev Biol. 2019.
PMID: 30902250
Free PMC article.
Review.
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Primary Cilia Direct Murine Articular Cartilage Tidemark Patterning Through Hedgehog Signaling and Ambulatory Load.
Rux D, Helbig K, Han B, Cortese C, Koyama E, Han L, Pacifici M.
Rux D, et al.
J Bone Miner Res. 2022 Jun;37(6):1097-1116. doi: 10.1002/jbmr.4506. Epub 2022 Feb 13.
J Bone Miner Res. 2022.
PMID: 35060644
Free PMC article.
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Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice.
Rux D, Helbig K, Koyama E, Pacifici M.
Rux D, et al.
Dev Biol. 2021 Sep;477:49-63. doi: 10.1016/j.ydbio.2021.05.007. Epub 2021 May 16.
Dev Biol. 2021.
PMID: 34010606
Free PMC article.
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