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Year Number of Results
2006 1
2008 1
2011 1
2012 1
2013 1
2014 5
2015 1
2016 2
2017 3
2018 1
2019 1
2020 3
2021 7
2022 9
2023 4
2024 1

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36 results

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Page 1
Identification of the RP11-21C4.1/SVEP1 gene pair associated with FAT2 mutations as a potential biomarker in gastric cancer.
Zhou L, Yang Y, Liu M, Gan Y, Liu R, Ren M, Zheng Y, Wang Y, Zhou Y. Zhou L, et al. Bioengineered. 2021 Dec;12(1):4361-4373. doi: 10.1080/21655979.2021.1953211. Bioengineered. 2021. PMID: 34308747 Free PMC article.
Gastric cancer (GC) is one of the most common malignancies worldwide. Despite rapid advances in systemic therapy, GC remains the third leading cause of cancer-related deaths. We aimed to identify a novel prognostic signature associated with FAT2 mutations in …
Gastric cancer (GC) is one of the most common malignancies worldwide. Despite rapid advances in systemic therapy, GC remains the thir …
FAT2 is a novel independent prognostic factor for the poor prognosis of gastric carcinoma.
Li L, Fu LQ, Wang HJ, Yan ZL, Yu XC, Wang YY. Li L, et al. Int J Clin Exp Pathol. 2017 Dec 1;10(12):11603-11609. eCollection 2017. Int J Clin Exp Pathol. 2017. PMID: 31966517 Free PMC article.
BACKGROUND: This study investigated the clinical implication of FAT2 in the progression, metastasis, and prognosis of gastric cancer. ...CONCLUSION: The expression of FAT2 in gastric cancer was significantly associated with lymph node and distant metas …
BACKGROUND: This study investigated the clinical implication of FAT2 in the progression, metastasis, and prognosis of gastric canc …
FAT2 mutation is associated with better prognosis and responsiveness to immunotherapy in uterine corpus endometrial carcinoma.
Wang Z, Xing L, Huang Y, Han P. Wang Z, et al. Cancer Med. 2023 Feb;12(3):3797-3811. doi: 10.1002/cam4.5119. Epub 2022 Aug 7. Cancer Med. 2023. PMID: 36812126 Free PMC article.
METHODS: UCEC samples from the Cancer Genome Atlas database were analyzed. We evaluated the impact of FAT2 gene mutation status and clinicopathological characteristics on the prognosis of UCEC patients and used univariate and multivariate Cox analysis risk scores to …
METHODS: UCEC samples from the Cancer Genome Atlas database were analyzed. We evaluated the impact of FAT2 gene mutation statu …
Function and cancer genomics of FAT family genes (review).
Katoh M. Katoh M. Int J Oncol. 2012 Dec;41(6):1913-8. doi: 10.3892/ijo.2012.1669. Epub 2012 Oct 17. Int J Oncol. 2012. PMID: 23076869 Free PMC article. Review.
FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation. FAT4 mRNA is repressed in breast cancer and lung cancer due to promoter hypermethylation. FAT4 gene is recurrently mutated in several types of human cancers, such as melanoma, pa …
FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation. FAT4 mRNA is repressed in breast cancer and lung …
deltaNp63alpha induces the expression of FAT2 and Slug to promote tumor invasion.
Dang TT, Westcott JM, Maine EA, Kanchwala M, Xing C, Pearson GW. Dang TT, et al. Oncotarget. 2016 May 10;7(19):28592-611. doi: 10.18632/oncotarget.8696. Oncotarget. 2016. PMID: 27081041 Free PMC article.
Notably, lung squamous cell carcinoma migration also required deltaNp63alpha dependent FAT2 and Slug expression, demonstrating that deltaNp63alpha promotes migration in multiple tumor types by inducing mesenchymal and non-mesenchymal genes. deltaNp63alpha activation of …
Notably, lung squamous cell carcinoma migration also required deltaNp63alpha dependent FAT2 and Slug expression, demonstrating that d …
Cell-surface marker discovery for lung cancer.
Cohen AS, Khalil FK, Welsh EA, Schabath MB, Enkemann SA, Davis A, Zhou JM, Boulware DC, Kim J, Haura EB, Morse DL. Cohen AS, et al. Oncotarget. 2017 Dec 7;8(69):113373-113402. doi: 10.18632/oncotarget.23009. eCollection 2017 Dec 26. Oncotarget. 2017. PMID: 29371917 Free PMC article.
Lung cancer is the leading cause of cancer deaths in the United States. ...To identify putative cell-surface markers, existing microarray gene expression data from patient specimens were analyzed to select markers with differential expression in lung cancer c …
Lung cancer is the leading cause of cancer deaths in the United States. ...To identify putative cell-surface markers, existing …
Comparative integromics on FAT1, FAT2, FAT3 and FAT4.
Katoh Y, Katoh M. Katoh Y, et al. Int J Mol Med. 2006 Sep;18(3):523-8. Int J Mol Med. 2006. PMID: 16865240
FAT1 mRNA was expressed in embryonic stem (ES) cells, neural tissues, gastric cancer, pancreatic cancer, colorectal cancer, breast cancer, lung cancer and brain tumors. FAT2 mRNA was expressed in infant brain, cerebellum, gastric cance …
FAT1 mRNA was expressed in embryonic stem (ES) cells, neural tissues, gastric cancer, pancreatic cancer, colorectal cancer …
Comprehensive Comparative Molecular Characterization of Young and Old Lung Cancer Patients.
Hu M, Tan J, Liu Z, Li L, Zhang H, Zhao D, Li B, Gao X, Che N, Zhang T. Hu M, et al. Front Oncol. 2022 Jan 12;11:806845. doi: 10.3389/fonc.2021.806845. eCollection 2021. Front Oncol. 2022. PMID: 35096611 Free PMC article.
BACKGROUND: Young lung cancer as a small subgroup of lung cancer has not been fully studied. ...Meanwhile, the heterogeneity and evolutionary degrees of the young lung cancer group were also lower than the old. The mutation spectrums of two groups exhibited v …
BACKGROUND: Young lung cancer as a small subgroup of lung cancer has not been fully studied. ...Meanwhile, the heterogeneity a …
Genetic landscape of esophageal squamous cell carcinoma.
Gao YB, Chen ZL, Li JG, Hu XD, Shi XJ, Sun ZM, Zhang F, Zhao ZR, Li ZT, Liu ZY, Zhao YD, Sun J, Zhou CC, Yao R, Wang SY, Wang P, Sun N, Zhang BH, Dong JS, Yu Y, Luo M, Feng XL, Shi SS, Zhou F, Tan FW, Qiu B, Li N, Shao K, Zhang LJ, Zhang LJ, Xue Q, Gao SG, He J. Gao YB, et al. Nat Genet. 2014 Oct;46(10):1097-102. doi: 10.1038/ng.3076. Epub 2014 Aug 24. Nat Genet. 2014. PMID: 25151357
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers. We performed exome sequencing on 113 tumor-normal pairs, yielding a mean of 82 non-silent mutations per tumor, and 8 cell lines. ...The Hippo and Notch pathways were dysregulated by mutations in FAT …
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers. We performed exome sequencing on 113 tumor-normal pairs, y …
History and progression of Fat cadherins in health and disease.
Zhang X, Liu J, Liang X, Chen J, Hong J, Li L, He Q, Cai X. Zhang X, et al. Onco Targets Ther. 2016 Dec 1;9:7337-7343. doi: 10.2147/OTT.S111176. eCollection 2016. Onco Targets Ther. 2016. PMID: 27942226 Free PMC article. Review.
As a member of the Ca(2+)-dependent adhesion super-family, Fat proteins were first described in the 1920s as an inheritable lethal mutant phenotype in Drosophila, consisting of four member proteins, FAT1, FAT2, FAT3, and FAT4, all of which are highly conserved in structure …
As a member of the Ca(2+)-dependent adhesion super-family, Fat proteins were first described in the 1920s as an inheritable lethal mutant ph …
36 results