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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 2
2009 1
2010 2
2011 1
2012 2
2013 2
2014 2
2015 2
2016 1
2017 2
2018 2
2019 3
2020 1
2021 6
2022 3
2023 5
2024 1

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36 results

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Page 1
Apposition of Fibroblasts With Metaplastic Gastric Cells Promotes Dysplastic Transition.
Lee SH, Contreras Panta EW, Gibbs D, Won Y, Min J, Zhang C, Roland JT, Hong SH, Sohn Y, Krystofiak E, Jang B, Ferri L, Sangwan V, Ragoussis J, Camilleri-Broët S, Caruso J, Chen-Tanyolac C, Strasser M, Gascard P, Tlsty TD, Huang S, Choi E, Goldenring JR. Lee SH, et al. Gastroenterology. 2023 Aug;165(2):374-390. doi: 10.1053/j.gastro.2023.04.038. Epub 2023 May 15. Gastroenterology. 2023. PMID: 37196797 Free PMC article.
BACKGROUND & AIMS: Elements of field cancerization, including atrophic gastritis, metaplasia, and dysplasia, promote gastric cancer development in association with chronic inflammation. ...The PDGFRalpha(+) subset expanded in metaplasia and cancer compare …
BACKGROUND & AIMS: Elements of field cancerization, including atrophic gastritis, metaplasia, and dysplasia, promote gastric c …
Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.
Vaes N, Schonkeren SL, Rademakers G, Holland AM, Koch A, Gijbels MJ, Keulers TG, de Wit M, Moonen L, Van der Meer JRM, van den Boezem E, Wolfs TGAM, Threadgill DW, Demmers J, Fijneman RJA, Jimenez CR, Vanden Berghe P, Smits KM, Rouschop KMA, Boesmans W, Hofstra RMW, Melotte V. Vaes N, et al. EMBO Rep. 2021 Jun 4;22(6):e51913. doi: 10.15252/embr.202051913. Epub 2021 Apr 23. EMBO Rep. 2021. PMID: 33890711 Free PMC article.
The N-Myc Downstream-Regulated Gene 4 (NDRG4), a prominent biomarker for colorectal cancer (CRC), is specifically expressed by enteric neurons. Considering that nerves are important members of the tumor microenvironment, we here establish different Ndrg4 knockout (Ndrg4(-/ …
The N-Myc Downstream-Regulated Gene 4 (NDRG4), a prominent biomarker for colorectal cancer (CRC), is specifically expressed by enteri …
Prognostic Utility of FBLN2 Expression in Patients With Urothelial Carcinoma.
Li WM, Chan TC, Huang SK, Wu WJ, Ke HL, Liang PI, Wei YC, Shiue YL, Li CF. Li WM, et al. Front Oncol. 2020 Oct 29;10:570340. doi: 10.3389/fonc.2020.570340. eCollection 2020. Front Oncol. 2020. PMID: 33194662 Free PMC article.
FBLN2 expression correlated with clinicopathological features and patient outcomes, including metastasis-free survival (MFS) and disease-specific survival (DSS). ...Kaplan-Meier analysis demonstrated associations of high FBLN2 expression with worse DSS (p < 0.001 …
FBLN2 expression correlated with clinicopathological features and patient outcomes, including metastasis-free survival (MFS) and dise …
Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH.
Zhu N, Swietlik EM, Welch CL, Pauciulo MW, Hagen JJ, Zhou X, Guo Y, Karten J, Pandya D, Tilly T, Lutz KA, Martin JM, Treacy CM, Rosenzweig EB, Krishnan U, Coleman AW, Gonzaga-Jauregui C, Lawrie A, Trembath RC, Wilkins MR; Regeneron Genetics Center; PAH Biobank Enrolling Centers’ Investigators; NIHR BioResource for Translational Research - Rare Diseases; National Cohort Study of Idiopathic and Heritable PAH; Morrell NW, Shen Y, Gräf S, Nichols WC, Chung WK. Zhu N, et al. Genome Med. 2021 May 10;13(1):80. doi: 10.1186/s13073-021-00891-1. Genome Med. 2021. PMID: 33971972 Free PMC article.
RESULTS: Seven genes with rare deleterious variants were associated with IPAH with false discovery rate smaller than 0.1: three known genes (BMPR2, GDF2, and TBX4), two recently identified candidate genes (SOX17, KDR), and two new candidate genes (fibulin 2, FBLN2; platele …
RESULTS: Seven genes with rare deleterious variants were associated with IPAH with false discovery rate smaller than 0.1: three known genes …
ITGBL1 promotes anoikis resistance and metastasis in human gastric cancer via the AKT/FBLN2 axis.
Shen K, Xia W, Wang K, Li J, Xu W, Liu H, Yang K, Zhu J, Wang J, Xi Q, Shi T, Li R. Shen K, et al. J Cell Mol Med. 2024 Feb;28(4):e18113. doi: 10.1111/jcmm.18113. J Cell Mol Med. 2024. PMID: 38332530 Free PMC article.
The resistance to anoikis plays a critical role in the metastatic progression of various types of malignancies, including gastric cancer (GC). Nevertheless, the precise mechanism behind anoikis resistance is not fully understood. ...Mechanistically, we proved that ITGBL1 h …
The resistance to anoikis plays a critical role in the metastatic progression of various types of malignancies, including gastric cancer …
Fibulin 2 Is Hypermethylated and Suppresses Tumor Cell Proliferation through Inhibition of Cell Adhesion and Extracellular Matrix Genes in Non-Small Cell Lung Cancer.
Ma Y, Nenkov M, Schröder DC, Abubrig M, Gassler N, Chen Y. Ma Y, et al. Int J Mol Sci. 2021 Oct 31;22(21):11834. doi: 10.3390/ijms222111834. Int J Mol Sci. 2021. PMID: 34769264 Free PMC article.
However, the function of FBLN2 in human non-small cell lung cancer (NSCLC) has not yet been elucidated. In this study, we found that FBLN2 was downregulated in 9 out of 11 lung cancer cell lines compared to normal bronchial epithelial cells, which was …
However, the function of FBLN2 in human non-small cell lung cancer (NSCLC) has not yet been elucidated. In this study, we foun …
Fibulin-2 is required for basement membrane integrity of mammary epithelium.
Ibrahim AM, Sabet S, El-Ghor AA, Kamel N, Anis SE, Morris JS, Stein T. Ibrahim AM, et al. Sci Rep. 2018 Sep 20;8(1):14139. doi: 10.1038/s41598-018-32507-x. Sci Rep. 2018. PMID: 30237579 Free PMC article.
In tissue sections of 65 breast cancers FBLN2 staining was lost around malignant cells with retained staining in the neighbouring histologically normal tissue margins. These results are consistent with a role of FBLN2 in mammary epithelial BM stability, and t …
In tissue sections of 65 breast cancers FBLN2 staining was lost around malignant cells with retained staining in the neighbour …
The expression level of fibulin-2 in the circulating RNA (ctRNA) of epithelial tumor cells of peripheral blood and tumor tissue of patients with metastatic lung cancer.
Avsar M, Tambas M, Yalniz Z, Akdeniz D, Tuncer SB, Kilic S, Sukruoglu Erdogan O, Ciftci R, Dagoglu N, Vatansever S, Yazici H. Avsar M, et al. Mol Biol Rep. 2019 Aug;46(4):4001-4008. doi: 10.1007/s11033-019-04846-z. Epub 2019 May 8. Mol Biol Rep. 2019. PMID: 31069614
The Fibulins are a recently discovered family of extracellular matrix proteins. In this study, expression levels of the fibulin-2 (FBLN2) gene and its role in the formation of different metastatic foci were investigated in lung cancer patients. ...In the study, the …
The Fibulins are a recently discovered family of extracellular matrix proteins. In this study, expression levels of the fibulin-2 (FBLN2 …
Fibulin-2 is involved in early extracellular matrix development of the outgrowing mouse mammary epithelium.
Olijnyk D, Ibrahim AM, Ferrier RK, Tsuda T, Chu ML, Gusterson BA, Stein T, Morris JS. Olijnyk D, et al. Cell Mol Life Sci. 2014 Oct;71(19):3811-28. doi: 10.1007/s00018-014-1577-4. Epub 2014 Feb 13. Cell Mol Life Sci. 2014. PMID: 24522256 Free PMC article.
Exposure to exogenous oestrogen (E2) or E2 plus progesterone (P) increased Fbln2 mRNA expression in the pubertal gland, indicating hormonal control. FBLN2 was co-expressed and co-localised with the proteoglycan versican (VCAN) and co-localised with laminin (LN), whi …
Exposure to exogenous oestrogen (E2) or E2 plus progesterone (P) increased Fbln2 mRNA expression in the pubertal gland, indicating ho …
Identification of novel methylated targets in colorectal cancer by microarray analysis and construction of co-expression network.
Li D, Guo J, Wang S, Zhu L, Shen Z. Li D, et al. Oncol Lett. 2017 Sep;14(3):2643-2648. doi: 10.3892/ol.2017.6506. Epub 2017 Jun 30. Oncol Lett. 2017. PMID: 28928808 Free PMC article.
The present study was conducted to investigate novel methylated targets in colorectal cancer (CRC). The mRNA expression profiles of GSE32323 in 17 cancer and non-cancerous tissues from CRC patients, as well as expression profiles of 5 CRC cell lines prior and …
The present study was conducted to investigate novel methylated targets in colorectal cancer (CRC). The mRNA expression profiles of G …
36 results