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FOXE1 Gene Dosage Affects Thyroid Cancer Histology and Differentiation In Vivo.
Credendino SC, Moccia C, Amendola E, D'Avino G, Di Guida L, Clery E, Greco A, Bellevicine C, Brunetti A, De Felice M, De Vita G. Credendino SC, et al. Int J Mol Sci. 2020 Dec 22;22(1):25. doi: 10.3390/ijms22010025. Int J Mol Sci. 2020. PMID: 33375029 Free PMC article.
Here, we describe the effects of FOXE1 gene dosage reduction on cancer phenotype in vivo. Mice heterozygous for FOXE1 null allele (FOXE1(+/-)) were crossed with a BRAF(V600E)-inducible cancer model to develop thyroid cancer in either a …
Here, we describe the effects of FOXE1 gene dosage reduction on cancer phenotype in vivo. Mice heterozygous for FOXE1 n …
FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1.
Morillo-Bernal J, Fernández LP, Santisteban P. Morillo-Bernal J, et al. Endocr Relat Cancer. 2020 Mar;27(3):137-151. doi: 10.1530/ERC-19-0156. Endocr Relat Cancer. 2020. PMID: 31846430 Free PMC article.
Here, we used a panel of human thyroid cancer-derived cell lines covering the spectrum of thyroid cancer phenotypes to examine FOXE1 expression and to test for correlations between FOXE1 expression, the allele frequency of two SNPs and a length polymor …
Here, we used a panel of human thyroid cancer-derived cell lines covering the spectrum of thyroid cancer phenotypes to examine …
FOXE1 polymorphism rs965513 predisposes to thyroid cancer in a European cohort.
Owens PW, McVeigh TP, Miller N, Guerin C, Sebag F, Quill D, Bell M, Kerin MJ, Lowery AJ. Owens PW, et al. Endocr Oncol. 2021 May 19;1(1):1-8. doi: 10.1530/EO-21-0003. eCollection 2021 Jan. Endocr Oncol. 2021. PMID: 37435181 Free PMC article.
OBJECTIVE: FOXE1 is an intronless gene on chromosome 9 which plays a significant role in thyroid morphogenesis. Mutations in FOXE1 are associated with thyroid phenotypes including congenital hypothyroidism, thyroid dysgenesis and thyroid cancer. ...
OBJECTIVE: FOXE1 is an intronless gene on chromosome 9 which plays a significant role in thyroid morphogenesis. Mutations in FOXE1 …
The high expression of FOXE1 in colorectal cancer predicts a promising prognosis: a retrospective study.
Liu X, Chen L, Wen F, Zheng S, Ge W. Liu X, et al. Clin Exp Med. 2023 Nov;23(7):3995-4001. doi: 10.1007/s10238-023-01096-z. Epub 2023 Jun 6. Clin Exp Med. 2023. PMID: 37278933
The Cox proportional risk regression model was used for multivariate analysis of prognostic factors in patients with CRC.Results The expression level of FOXE1 in colorectal cancer was higher than that in the normal mucosa adjacent to cancer, although the diff …
The Cox proportional risk regression model was used for multivariate analysis of prognostic factors in patients with CRC.Results The express …
FOXE1 inhibits cell proliferation, migration and invasion of papillary thyroid cancer by regulating PDGFA.
Ding Z, Ke R, Zhang Y, Fan Y, Fan J. Ding Z, et al. Mol Cell Endocrinol. 2019 Aug 1;493:110420. doi: 10.1016/j.mce.2019.03.010. Epub 2019 May 23. Mol Cell Endocrinol. 2019. PMID: 31129275
However, the biological functions of FOXE1 in papillary thyroid cancer (PTC) remain unclear. MATERIALS AND METHODS: In this study, the level of FOXE1 expression was examined in human PTC tissues and cells. ...Thus, FOXE1 could serve as a prognostic bio …
However, the biological functions of FOXE1 in papillary thyroid cancer (PTC) remain unclear. MATERIALS AND METHODS: In this st …
FOXE1-Dependent Regulation of Macrophage Chemotaxis by Thyroid Cells In Vitro and In Vivo.
Credendino SC, De Menna M, Cantone I, Moccia C, Esposito M, Di Guida L, De Felice M, De Vita G. Credendino SC, et al. Int J Mol Sci. 2021 Jul 17;22(14):7666. doi: 10.3390/ijms22147666. Int J Mol Sci. 2021. PMID: 34299284 Free PMC article.
Forkhead box E1 (FOXE1) is a lineage-restricted transcription factor involved in thyroid cancer susceptibility. ...We then asked if FOXE1 was able to regulate macrophage infiltration in thyroid cancers in vivo by using a mouse model of cancer, e …
Forkhead box E1 (FOXE1) is a lineage-restricted transcription factor involved in thyroid cancer susceptibility. ...We then ask …
Human FOX gene family (Review).
Katoh M, Katoh M. Katoh M, et al. Int J Oncol. 2004 Nov;25(5):1495-500. Int J Oncol. 2004. PMID: 15492844 Review.
FOXH1 and FOXO1 mRNAs are expressed in human embryonic stem (ES) cells. FOXC1, FOXC2, FOXE1, FOXE3, FOXL2, FOXN1, FOXP2 and FOXP3 genes are mutated in human congenital disorders. FOXA1 gene is amplified and over-expressed in esophageal and lung cancer. FOXM1 gene is …
FOXH1 and FOXO1 mRNAs are expressed in human embryonic stem (ES) cells. FOXC1, FOXC2, FOXE1, FOXE3, FOXL2, FOXN1, FOXP2 and FOXP3 gen …
FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer.
Dai W, Meng X, Mo S, Xiang W, Xu Y, Zhang L, Wang R, Li Q, Cai G. Dai W, et al. Cell Commun Signal. 2020 Jan 9;18(1):7. doi: 10.1186/s12964-019-0502-8. Cell Commun Signal. 2020. PMID: 31918722 Free PMC article.
BACKGROUND: Low expression of FOXE1, a member of Forkhead box (FOX) transcription factor family that plays vital roles in cancers, contributes to poor prognosis of colorectal cancer (CRC) patients. ...CRC tissue specimens were used to determine the clinical a …
BACKGROUND: Low expression of FOXE1, a member of Forkhead box (FOX) transcription factor family that plays vital roles in cancers …
Somatic Mutations of FOXE1 in Papillary Thyroid Cancer.
Mond M, Bullock M, Yao Y, Clifton-Bligh RJ, Gilfillan C, Fuller PJ. Mond M, et al. Thyroid. 2015 Aug;25(8):904-10. doi: 10.1089/thy.2015.0030. Epub 2015 Jun 19. Thyroid. 2015. PMID: 25950909
BACKGROUND: Population-based studies have demonstrated an association of single nucleotide polymorphisms close to the thyroid transcription factor forkhead box E1 (FOXE1) gene with thyroid cancer. The dysregulation of forkhead proteins is increasingly recognized to …
BACKGROUND: Population-based studies have demonstrated an association of single nucleotide polymorphisms close to the thyroid transcription …
MiRNA-802 inhibits the metastasis of colorectal cancer by targeting FOXE1.
Zhang Y, Ma LN, Xie Y. Zhang Y, et al. Eur Rev Med Pharmacol Sci. 2020 Feb;24(4):1778-1785. doi: 10.26355/eurrev_202002_20355. Eur Rev Med Pharmacol Sci. 2020. PMID: 32141546 Free article.
Meanwhile, the expression of FOXE1 was negatively correlated with miRNA-802 in CRC tissues. A higher level of FOXE1 indicated the worse prognosis of CRC patients. ...Furthermore, miRNA-802 alleviates the malignant progression of CRC via negatively regulating FOXE …
Meanwhile, the expression of FOXE1 was negatively correlated with miRNA-802 in CRC tissues. A higher level of FOXE1 indicated …
144 results