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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 1
2004 5
2005 10
2006 9
2007 14
2008 20
2009 16
2010 13
2011 22
2012 26
2013 23
2014 37
2015 37
2016 40
2017 30
2018 34
2019 39
2020 37
2021 20
2022 27
2023 28
2024 11

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445 results

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Page 1
NAT10/ac4C/FOXP1 Promotes Malignant Progression and Facilitates Immunosuppression by Reprogramming Glycolytic Metabolism in Cervical Cancer.
Chen X, Hao Y, Liu Y, Zhong S, You Y, Ao K, Chong T, Luo X, Yin M, Ye M, He H, Lu A, Chen J, Li X, Zhang J, Guo X. Chen X, et al. Adv Sci (Weinh). 2023 Nov;10(32):e2302705. doi: 10.1002/advs.202302705. Epub 2023 Oct 11. Adv Sci (Weinh). 2023. PMID: 37818745 Free PMC article.
Immunotherapy has recently emerged as the predominant therapeutic approach for cervical cancer (CCa), driven by the groundbreaking clinical achievements of immune checkpoint inhibitors (ICIs), such as anti-PD-1/PD-L1 antibodies. ...Moreover, NAT10/ac4C/FOXP1 axis ac …
Immunotherapy has recently emerged as the predominant therapeutic approach for cervical cancer (CCa), driven by the groundbreaking cl …
FOXP1 inhibits pancreatic cancer growth by transcriptionally regulating IRF1 expression.
Wang L, Luo P, Yang Z, Zhong X, Ji C. Wang L, et al. PLoS One. 2023 Mar 23;18(3):e0280794. doi: 10.1371/journal.pone.0280794. eCollection 2023. PLoS One. 2023. PMID: 36952469 Free PMC article.
However, the function and molecular mechanism of FOXP1 in pancreatic cancer (PC) remain unclear. Here, we report that PC patients with FOXP1 overexpression had a higher survival rate compared to patients with low- FOXP1 expression. Additionally, high e …
However, the function and molecular mechanism of FOXP1 in pancreatic cancer (PC) remain unclear. Here, we report that PC patie …
miR-34a-FOXP1 Loop in Ovarian Cancer.
Dirimtekin E, Mortoglou M, Alavanda C, Benomar Yemlahi A, Arslan Ates E, Guney I, Uysal-Onganer P. Dirimtekin E, et al. ACS Omega. 2023 Jul 18;8(30):27743-27750. doi: 10.1021/acsomega.3c03867. eCollection 2023 Aug 1. ACS Omega. 2023. PMID: 37546627 Free PMC article.
Ovarian cancer (OC) is the main cause of gynecological cancer mortality in most developed countries. microRNA (miR) expression dysregulation has been highlighted in human cancers, and miR-34a is found to be downregulated and associated with inhibition of tumo …
Ovarian cancer (OC) is the main cause of gynecological cancer mortality in most developed countries. microRNA (miR) expression …
FOXP1 and estrogen signaling in breast cancer.
Ijichi N, Ikeda K, Horie-Inoue K, Inoue S. Ijichi N, et al. Vitam Horm. 2013;93:203-12. doi: 10.1016/B978-0-12-416673-8.00006-X. Vitam Horm. 2013. PMID: 23810008 Review.
Breast cancers are considered to be primarily regulated by estrogen signaling pathways because estrogen-dependent proliferation is observed in the majority of breast cancer cases. ...The functions of FOXP1 and FOXA1 have been characterized in cultured cells; …
Breast cancers are considered to be primarily regulated by estrogen signaling pathways because estrogen-dependent proliferation is ob …
FOXP1: a potential therapeutic target in cancer.
Koon HB, Ippolito GC, Banham AH, Tucker PW. Koon HB, et al. Expert Opin Ther Targets. 2007 Jul;11(7):955-65. doi: 10.1517/14728222.11.7.955. Expert Opin Ther Targets. 2007. PMID: 17614763 Free PMC article. Review.
In contrast, FOXP1 localises to a tumour suppressor locus at 3p14.1 and loss of FOXP1 expression in breast cancer is associated with a worse outcome, suggesting FOXP1 may function as a tumour suppressor in other tissue types. These data suggest that …
In contrast, FOXP1 localises to a tumour suppressor locus at 3p14.1 and loss of FOXP1 expression in breast cancer is as …
Integrative genomic profiling of human prostate cancer.
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, Wilson M, Socci ND, Lash AE, Heguy A, Eastham JA, Scher HI, Reuter VE, Scardino PT, Sander C, Sawyers CL, Gerald WL. Taylor BS, et al. Cancer Cell. 2010 Jul 13;18(1):11-22. doi: 10.1016/j.ccr.2010.05.026. Epub 2010 Jun 24. Cancer Cell. 2010. PMID: 20579941 Free PMC article.
Annotation of prostate cancer genomes provides a foundation for discoveries that can impact disease understanding and treatment. Concordant assessment of DNA copy number, mRNA expression, and focused exon resequencing in 218 prostate cancer tumors identified the nuc …
Annotation of prostate cancer genomes provides a foundation for discoveries that can impact disease understanding and treatment. Conc …
FoxP1 is a transcriptional repressor associated with cancer cachexia that induces skeletal muscle wasting and weakness.
Neyroud D, Nosacka RL, Callaway CS, Trevino JG, Hu H, Judge SM, Judge AR. Neyroud D, et al. J Cachexia Sarcopenia Muscle. 2021 Apr;12(2):421-442. doi: 10.1002/jcsm.12666. Epub 2021 Feb 1. J Cachexia Sarcopenia Muscle. 2021. PMID: 33527776 Free PMC article.
Herein, we investigated the biological significance of Forkhead box P1 (FoxP1), a transcriptional repressor that we demonstrate is up-regulated in skeletal muscle in multiple models of cancer cachexia and in cachectic cancer patients. ...To determine the requ …
Herein, we investigated the biological significance of Forkhead box P1 (FoxP1), a transcriptional repressor that we demonstrate is up …
A novel epigenetic regulation of circFoxp1 on Foxp1 in colon cancer cells.
Luo Y, Liu F, Ma J, Fu Y, Gui R. Luo Y, et al. Cell Death Dis. 2020 Sep 19;11(9):782. doi: 10.1038/s41419-020-03007-6. Cell Death Dis. 2020. PMID: 32951006 Free PMC article.
Foxp1 is a tumor suppressor in colon cancer. However, circFoxp1 derived from Foxp1 is an oncogene. ...We discovered a novel epigenetic pathway that circFoxp1 regulated Foxp1 in colon cancer cells. CircFoxp1 may regulate DNA methylation and demet …
Foxp1 is a tumor suppressor in colon cancer. However, circFoxp1 derived from Foxp1 is an oncogene. ...We discovered a n …
FOXP1 negatively regulates tumor infiltrating lymphocyte migration in human breast cancer.
De Silva P, Garaud S, Solinas C, de Wind A, Van den Eyden G, Jose V, Gu-Trantien C, Migliori E, Boisson A, Naveaux C, Duvillier H, Craciun L, Larsimont D, Piccart-Gebhart M, Willard-Gallo K. De Silva P, et al. EBioMedicine. 2019 Jan;39:226-238. doi: 10.1016/j.ebiom.2018.11.066. Epub 2018 Dec 20. EBioMedicine. 2019. PMID: 30579865 Free PMC article.
This study investigated FOXP1-mediated regulation of tumor infiltrating lymphocytes (TIL) in untreated primary breast cancer (BC). ...FOXP1(hi) tumors were significantly associated with lower TIL and fewer tertiary lymphoid structures (TLS) compared to FOX …
This study investigated FOXP1-mediated regulation of tumor infiltrating lymphocytes (TIL) in untreated primary breast cancer ( …
Expression of FOXP1 and Colorectal Cancer Prognosis.
De Smedt L, Palmans S, Govaere O, Moisse M, Boeckx B, De Hertogh G, Prenen H, Van Cutsem E, Tejpar S, Tousseyn T, Sagaert X. De Smedt L, et al. Lab Med. 2015 Fall;46(4):299-311. doi: 10.1309/LM7IHV2NJI1PHMXC. Lab Med. 2015. PMID: 26489674
BACKGROUND: Forkhead box gene P1 (FOXP1) has proven to be a valuable prognostic biomarker in lymphomas, but little is known about this gene in colorectal cancer (CRC). ...We found no chromosomal aberrations involving FOXP1 in individuals with FOXP1 neg …
BACKGROUND: Forkhead box gene P1 (FOXP1) has proven to be a valuable prognostic biomarker in lymphomas, but little is known about thi …
445 results