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FSIP1 regulates autophagy in breast cancer.
Liu C, Sun L, Yang J, Liu T, Yang Y, Kim SM, Ou X, Wang Y, Sun L, Zaidi M, New MI, Yuen T, Guo Q. Liu C, et al. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13075-13080. doi: 10.1073/pnas.1809681115. Epub 2018 Dec 3. Proc Natl Acad Sci U S A. 2018. PMID: 30509973 Free PMC article.
Fibrous sheath interacting protein 1 (FSIP1) is a cancer antigen expressed in the majority of breast cancer tissues and is associated with poor prognosis. However, the role of FSIP1 in the progression and drug sensitivity of triple-negative breast c …
Fibrous sheath interacting protein 1 (FSIP1) is a cancer antigen expressed in the majority of breast cancer tissues and …
Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization.
Yan M, Wang J, Ren Y, Li L, He W, Zhang Y, Liu T, Li Z. Yan M, et al. Cell Death Dis. 2019 Feb 27;10(3):204. doi: 10.1038/s41419-018-1248-8. Cell Death Dis. 2019. PMID: 30814489 Free PMC article.
We analyzed FSIP1 expression in the breast cancer and para-tumor tissues by immunohistochemistry. ...FSIP1 knockout in breast cancer cells significantly increased their sensitivity to docetaxel both in vitro and in vivo. ...
We analyzed FSIP1 expression in the breast cancer and para-tumor tissues by immunohistochemistry. ...FSIP1 knockout in …
FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.
Liu T, Zhang H, Sun L, Zhao D, Liu P, Yan M, Zaidi N, Izadmehr S, Gupta A, Abu-Amer W, Luo M, Yang J, Ou X, Wang Y, Bai X, Wang Y, New MI, Zaidi M, Yuen T, Liu C. Liu T, et al. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7683-7688. doi: 10.1073/pnas.1621486114. Epub 2017 Jul 3. Proc Natl Acad Sci U S A. 2017. PMID: 28674022 Free PMC article.
Fibrous sheath interacting protein 1 (FSIP1), a spermatogenesis-related testicular antigen, is expressed in abundance in breast cancers, particularly in those overexpressing human epidermal growth factor receptor 2 (HER2); however, little is known about its role in …
Fibrous sheath interacting protein 1 (FSIP1), a spermatogenesis-related testicular antigen, is expressed in abundance in breast ca …
FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.
Chen G, Sun L, Gu X, Ai L, Yang J, Zhang Z, Hou P, Wang Y, Ou X, Jiang X, Qiao X, Ma Q, Niu N, Xue J, Zhang H, Yang Y, Liu C. Chen G, et al. Sci China Life Sci. 2023 Dec;66(12):2805-2817. doi: 10.1007/s11427-023-2343-y. Epub 2023 Jul 14. Sci China Life Sci. 2023. PMID: 37460715
CDK4/6 inhibitors are routinely recommended agents for the treatment of advanced HR(+)HER2(-) breast cancer. However, their therapeutic effectiveness in triple-negative breast cancer (TNBC) remains controversial. ...High FSIP1 expression level was related to …
CDK4/6 inhibitors are routinely recommended agents for the treatment of advanced HR(+)HER2(-) breast cancer. However, their therapeut …
Expression and clinicopathological significance of FSIP1 in breast cancer.
Zhang H, Luo M, Jin Z, Wang D, Sun M, Zhao X, Zhao Z, Lei H, Li M, Liu C. Zhang H, et al. Oncotarget. 2015 Apr 30;6(12):10658-66. doi: 10.18632/oncotarget.3381. Oncotarget. 2015. PMID: 25826084 Free PMC article.
AIM: To investigate the clinicopathological significance of the expression of fibrous sheath interacting protein 1 (FSIP1) in breast cancer, serum samples, and wound fluid from patients with breast cancer. ...CONCLUSION: FSIP1 may play an important rol …
AIM: To investigate the clinicopathological significance of the expression of fibrous sheath interacting protein 1 (FSIP1) in breast …
FSIP1 is correlated with estrogen receptor status and poor prognosis.
Li X, Song X, Ma J, Zhao Y, Jiang Q, Zhao Z, Li M. Li X, et al. Mol Carcinog. 2020 Jan;59(1):126-135. doi: 10.1002/mc.23134. Epub 2019 Nov 12. Mol Carcinog. 2020. PMID: 31713931
We analyzed the expression and clinical significance of FSIP1 in human breast cancer databases. A comprehensive analysis of 1094 gene expression profiles of breast cancer in The Cancer Genome Atlas revealed that FSIP1 overexpression correlated w …
We analyzed the expression and clinical significance of FSIP1 in human breast cancer databases. A comprehensive analysis of 10 …
FSIP1 Is Associated with Poor Prognosis and Can Be Used to Construct a Prognostic Model in Gastric Cancer.
Yan X, Dai J, Han Y, You Q, Liu Y. Yan X, et al. Dis Markers. 2022 Jun 3;2022:2478551. doi: 10.1155/2022/2478551. eCollection 2022. Dis Markers. 2022. PMID: 35692888 Free PMC article.
KEGG and GO analyses were used to explore the molecular mechanism of FSIP1 in GC progression. This study further retrospectively analyzed 166 clinical samples of GC from Harbin Medical University Cancer Hospital and evaluated the expression level of FSIP1 by …
KEGG and GO analyses were used to explore the molecular mechanism of FSIP1 in GC progression. This study further retrospectively anal …
Elevated expression of cancer/testis antigen FSIP1 in ER-positive breast tumors.
Chapman KB, Prendes MJ, Kidd JL, Sternberg H, West MD, Wagner J. Chapman KB, et al. Biomark Med. 2013 Aug;7(4):601-11. doi: 10.2217/bmm.13.58. Biomark Med. 2013. PMID: 23905897
Quantitative real-time PCR confirmed the elevated expression of FSIP1 mRNA in breast tumors and revealed a significant correlation with ER-positive status. ...CONCLUSION: The prevalence and uniformity of FSIP1 expression in breast tumors, taken together with the hig …
Quantitative real-time PCR confirmed the elevated expression of FSIP1 mRNA in breast tumors and revealed a significant correlation wi …
Elevated mRNA level indicates FSIP1 promotes EMT and gastric cancer progression by regulating fibroblasts in tumor microenvironment.
Liu Y, Jiang X, Yan X, Yang S, Bian X, Wang Y, You Q, Zhang L. Liu Y, et al. Open Med (Wars). 2024 May 10;19(1):20240964. doi: 10.1515/med-2024-0964. eCollection 2024. Open Med (Wars). 2024. PMID: 38737444 Free PMC article.
Fiber sheath interaction protein 1 (FSIP1) plays a crucial role in cancer development and occurrence, but its influence on gastric cancer is still unclear. ...FSIP1 may take a role of the occurrence and could be a potential therapeutic target and offer …
Fiber sheath interaction protein 1 (FSIP1) plays a crucial role in cancer development and occurrence, but its influence on gas …
Clinical significance of expression of fibrous sheath interacting protein 1 in colon cancer.
Wu HY, Yang B, Geng DH. Wu HY, et al. World J Gastrointest Oncol. 2020 Jun 15;12(6):677-686. doi: 10.4251/wjgo.v12.i6.677. World J Gastrointest Oncol. 2020. PMID: 32699582 Free PMC article.
Fibrous sheath interacting protein 1 (FSIP1) is a newly discovered oncogene that is frequently activated in a variety of tumours such as breast cancer and bladder cancer. However, the clinical significance of FSIP1 in colon cancer is unclear. In …
Fibrous sheath interacting protein 1 (FSIP1) is a newly discovered oncogene that is frequently activated in a variety of tumours such …
21 results