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Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.
Höpner S, Dickhaut K, Hofstätter M, Krämer H, Rückerl D, Söderhäll JA, Gupta S, Marin-Esteban V, Kühne R, Freund C, Jung G, Falk K, Rötzschke O. Höpner S, et al. Among authors: falk k. J Biol Chem. 2006 Dec 15;281(50):38535-42. doi: 10.1074/jbc.M606437200. Epub 2006 Sep 27. J Biol Chem. 2006. PMID: 17005558 Free article.
Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Günther S, Schlundt A, Sticht J, Roske Y, Heinemann U, Wiesmüller KH, Jung G, Falk K, Rötzschke O, Freund C. Günther S, et al. Among authors: falk k. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22219-24. doi: 10.1073/pnas.1014708107. Epub 2010 Nov 29. Proc Natl Acad Sci U S A. 2010. PMID: 21115828 Free PMC article.
473 results