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Putting the brakes on FOXO1 in fat.
Kim JJ, Fan W, Olefsky JM. Kim JJ, et al. Among authors: fan w. EMBO J. 2012 May 16;31(10):2240-1. doi: 10.1038/emboj.2012.116. Epub 2012 Apr 17. EMBO J. 2012. PMID: 22510885 Free PMC article.
Free fatty acids induce Lhb mRNA but suppress Fshb mRNA in pituitary LβT2 gonadotropes and diet-induced obesity reduces FSH levels in male mice and disrupts the proestrous LH/FSH surge in female mice.
Sharma S, Morinaga H, Hwang V, Fan W, Fernandez MO, Varki N, Olefsky JM, Webster NJ. Sharma S, et al. Among authors: fan w. Endocrinology. 2013 Jun;154(6):2188-99. doi: 10.1210/en.2012-2218. Epub 2013 Mar 22. Endocrinology. 2013. PMID: 23525221 Free PMC article.
6,510 results