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Substrate deconstruction and the nonadditivity of enzyme recognition.
Barelier S, Cummings JA, Rauwerdink AM, Hitchcock DS, Farelli JD, Almo SC, Raushel FM, Allen KN, Shoichet BK. Barelier S, et al. Among authors: farelli jd. J Am Chem Soc. 2014 May 21;136(20):7374-82. doi: 10.1021/ja501354q. Epub 2014 May 12. J Am Chem Soc. 2014. PMID: 24791931 Free PMC article.
Panoramic view of a superfamily of phosphatases through substrate profiling.
Huang H, Pandya C, Liu C, Al-Obaidi NF, Wang M, Zheng L, Toews Keating S, Aono M, Love JD, Evans B, Seidel RD, Hillerich BS, Garforth SJ, Almo SC, Mariano PS, Dunaway-Mariano D, Allen KN, Farelli JD. Huang H, et al. Among authors: farelli jd. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E1974-83. doi: 10.1073/pnas.1423570112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848029 Free PMC article.
Enzyme promiscuity: engine of evolutionary innovation.
Pandya C, Farelli JD, Dunaway-Mariano D, Allen KN. Pandya C, et al. Among authors: farelli jd. J Biol Chem. 2014 Oct 31;289(44):30229-30236. doi: 10.1074/jbc.R114.572990. Epub 2014 Sep 10. J Biol Chem. 2014. PMID: 25210039 Free PMC article. Review.
Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis.
Koo BM, Kritikos G, Farelli JD, Todor H, Tong K, Kimsey H, Wapinski I, Galardini M, Cabal A, Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA. Koo BM, et al. Among authors: farelli jd. Cell Syst. 2017 Mar 22;4(3):291-305.e7. doi: 10.1016/j.cels.2016.12.013. Epub 2017 Feb 8. Cell Syst. 2017. PMID: 28189581 Free PMC article.
On the unyielding hydrophobic core of villin headpiece.
Brown JW, Farelli JD, McKnight CJ. Brown JW, et al. Among authors: farelli jd. Protein Sci. 2012 May;21(5):647-54. doi: 10.1002/pro.2048. Epub 2012 Mar 30. Protein Sci. 2012. PMID: 22467489 Free PMC article.
17 results