Farhat MR - Search Results

1

Estimation of country-specific tuberculosis resistance antibiograms using pathogen genomics and machine learning.

Dixit A, Freschi L, Vargas R, Gröschel MI, Nakhoul M, Tahseen S, Alam SMM, Kamal SMM, Skrahina A, Basilio RP, Lim DR, Ismail N, Farhat MR. Dixit A, et al. Among authors: farhat mr. BMJ Glob Health. 2024 Mar 28;9(3):e013532. doi: 10.1136/bmjgh-2023-013532. BMJ Glob Health. 2024. PMID: 38548342 Free PMC article.

2

DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis.

Yang Y, Walker TM, Walker AS, Wilson DJ, Peto TEA, Crook DW, Shamout F; CRyPTIC Consortium; Zhu T, Clifton DA. Yang Y, et al. Bioinformatics. 2019 Sep 15;35(18):3240-3249. doi: 10.1093/bioinformatics/btz067. Bioinformatics. 2019. PMID: 30689732 Free PMC article.

3

Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting.

Dixit A, Freschi L, Vargas R, Calderon R, Sacchettini J, Drobniewski F, Galea JT, Contreras C, Yataco R, Zhang Z, Lecca L, Kolokotronis SO, Mathema B, Farhat MR. Dixit A, et al. Among authors: farhat mr. Sci Rep. 2019 Apr 3;9(1):5602. doi: 10.1038/s41598-019-41967-8. Sci Rep. 2019. PMID: 30944370 Free PMC article.

4

Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction.

Chen ML, Doddi A, Royer J, Freschi L, Schito M, Ezewudo M, Kohane IS, Beam A, Farhat M. Chen ML, et al. EBioMedicine. 2019 May;43:356-369. doi: 10.1016/j.ebiom.2019.04.016. Epub 2019 Apr 29. EBioMedicine. 2019. PMID: 31047860 Free PMC article.

5

GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions.

Farhat MR, Freschi L, Calderon R, Ioerger T, Snyder M, Meehan CJ, de Jong B, Rigouts L, Sloutsky A, Kaur D, Sunyaev S, van Soolingen D, Shendure J, Sacchettini J, Murray M. Farhat MR, et al. Nat Commun. 2019 May 13;10(1):2128. doi: 10.1038/s41467-019-10110-6. Nat Commun. 2019. PMID: 31086182 Free PMC article.

6

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

Hunt M, Bradley P, Lapierre SG, Heys S, Thomsit M, Hall MB, Malone KM, Wintringer P, Walker TM, Cirillo DM, Comas I, Farhat MR, Fowler P, Gardy J, Ismail N, Kohl TA, Mathys V, Merker M, Niemann S, Omar SV, Sintchenko V, Smith G, van Soolingen D, Supply P, Tahseen S, Wilcox M, Arandjelovic I, Peto TEA, Crook DW, Iqbal Z. Hunt M, et al. Among authors: farhat mr. Wellcome Open Res. 2019 Dec 2;4:191. doi: 10.12688/wellcomeopenres.15603.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 32055708 Free PMC article.

7

Antibiotic treatment and selection for glpK mutations in patients with active tuberculosis disease.

Vargas R Jr, Farhat MR. Vargas R Jr, et al. Among authors: farhat mr. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):3910-3912. doi: 10.1073/pnas.1920788117. Epub 2020 Feb 19. Proc Natl Acad Sci U S A. 2020. PMID: 32075922 Free PMC article. No abstract available.

8

The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia.

Gröschel MI, Meehan CJ, Barilar I, Diricks M, Gonzaga A, Steglich M, Conchillo-Solé O, Scherer IC, Mamat U, Luz CF, De Bruyne K, Utpatel C, Yero D, Gibert I, Daura X, Kampmeier S, Rahman NA, Kresken M, van der Werf TS, Alio I, Streit WR, Zhou K, Schwartz T, Rossen JWA, Farhat MR, Schaible UE, Nübel U, Rupp J, Steinmann J, Niemann S, Kohl TA. Gröschel MI, et al. Among authors: farhat mr. Nat Commun. 2020 Apr 27;11(1):2044. doi: 10.1038/s41467-020-15123-0. Nat Commun. 2020. PMID: 32341346 Free PMC article.

9

Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.

Kadura S, King N, Nakhoul M, Zhu H, Theron G, Köser CU, Farhat M. Kadura S, et al. J Antimicrob Chemother. 2020 Aug 1;75(8):2031-2043. doi: 10.1093/jac/dkaa136. J Antimicrob Chemother. 2020. PMID: 32361756 Free PMC article.

10

Mentorship at a distance.

Rankin NA, Gröschel MI, Farhat MR. Rankin NA, et al. Among authors: farhat mr. Science. 2020 Oct 23;370(6515):494. doi: 10.1126/science.370.6515.494. Science. 2020. PMID: 33093113 No abstract available.

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