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A novel mutation in the leptin gene (W121X) in an Egyptian family.
Mazen I, Amr K, Tantawy S, Farooqi IS, El Gammal M. Mazen I, et al. Among authors: farooqi is. Mol Genet Metab Rep. 2014 Nov 11;1:474-476. doi: 10.1016/j.ymgmr.2014.10.002. eCollection 2014. Mol Genet Metab Rep. 2014. PMID: 27896126 Free PMC article.
Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.
Funcke JB, Moepps B, Roos J, von Schnurbein J, Verstraete K, Fröhlich-Reiterer E, Kohlsdorf K, Nunziata A, Brandt S, Tsirigotaki A, Dansercoer A, Suppan E, Haris B, Debatin KM, Savvides SN, Farooqi IS, Hussain K, Gierschik P, Fischer-Posovszky P, Wabitsch M. Funcke JB, et al. Among authors: farooqi is. N Engl J Med. 2023 Jun 15;388(24):2253-2261. doi: 10.1056/NEJMoa2204041. N Engl J Med. 2023. PMID: 37314706
Classification of Congenital Leptin Deficiency.
von Schnurbein J, Zorn S, Nunziata A, Brandt S, Moepps B, Funcke JB, Hussain K, Farooqi IS, Fischer-Posovszky P, Wabitsch M. von Schnurbein J, et al. Among authors: farooqi is. J Clin Endocrinol Metab. 2024 Mar 12:dgae149. doi: 10.1210/clinem/dgae149. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38470203
Antidiabetic effects of IGFBP2, a leptin-regulated gene.
Hedbacker K, Birsoy K, Wysocki RW, Asilmaz E, Ahima RS, Farooqi IS, Friedman JM. Hedbacker K, et al. Among authors: farooqi is. Cell Metab. 2010 Jan;11(1):11-22. doi: 10.1016/j.cmet.2009.11.007. Cell Metab. 2010. PMID: 20074524 Free article.
Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Clément K, van den Akker E, Argente J, Bahm A, Chung WK, Connors H, De Waele K, Farooqi IS, Gonneau-Lejeune J, Gordon G, Kohlsdorf K, Poitou C, Puder L, Swain J, Stewart M, Yuan G, Wabitsch M, Kühnen P; Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Clément K, et al. Among authors: farooqi is. Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. doi: 10.1016/S2213-8587(20)30364-8. Epub 2020 Oct 30. Lancet Diabetes Endocrinol. 2020. PMID: 33137293 Clinical Trial.
229 results