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Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X. Wu X, et al. Cell Death Dis. 2023 Aug 30;14(8):577. doi: 10.1038/s41419-023-06104-4. Cell Death Dis. 2023. PMID: 37648705 Free PMC article.
This study aims to investigate the sources of Fcn B and its mechanism in BLM-induced lung injury. WT, Fcna(-/-), and Fcnb(-/-) mice were selected to construct the BLM-induced lung injury model. ...
This study aims to investigate the sources of Fcn B and its mechanism in BLM-induced lung injury. WT, Fcna(-/-), and Fcnb(-/-) mice w …
Accurate detection of Covid-19 patients based on Feature Correlated Naive Bayes (FCNB) classification strategy.
Mansour NA, Saleh AI, Badawy M, Ali HA. Mansour NA, et al. J Ambient Intell Humaniz Comput. 2022;13(1):41-73. doi: 10.1007/s12652-020-02883-2. Epub 2021 Jan 15. J Ambient Intell Humaniz Comput. 2022. PMID: 33469467 Free PMC article.
In this study, a new COVID-19 diagnosis strategy called Feature Correlated Naive Bayes (FCNB) has been introduced. The FCNB consists of four phases, which are; Feature Selection Phase (FSP), Feature Clustering Phase (FCP), Master Feature Weighting Phase (MFWP), and …
In this study, a new COVID-19 diagnosis strategy called Feature Correlated Naive Bayes (FCNB) has been introduced. The FCNB co …
Ficolin-B marks apoptotic and necrotic cells.
Schmid M, Hunold K, Weber-Steffens D, Männel DN. Schmid M, et al. Immunobiology. 2012 Jun;217(6):610-5. doi: 10.1016/j.imbio.2011.10.020. Epub 2011 Nov 7. Immunobiology. 2012. PMID: 22119501
This binding was calcium-dependent and could be competitively inhibited by acetylated BSA, a classical binding substrate of FcnB. In addition, DNA inhibited binding of FcnB to apoptotic and necrotic cells, indicating that DNA exposed by dying cells could also be a l …
This binding was calcium-dependent and could be competitively inhibited by acetylated BSA, a classical binding substrate of FcnB. In …
LncRNA AK036396 Inhibits Maturation and Accelerates Immunosuppression of Polymorphonuclear Myeloid-Derived Suppressor Cells by Enhancing the Stability of Ficolin B.
Tian X, Zheng Y, Yin K, Ma J, Tian J, Zhang Y, Mao L, Xu H, Wang S. Tian X, et al. Cancer Immunol Res. 2020 Apr;8(4):565-577. doi: 10.1158/2326-6066.CIR-19-0595. Epub 2020 Feb 26. Cancer Immunol Res. 2020. PMID: 32102837
LncRNA AK036396 knockdown attenuated Fcnb protein stability in a manner dependent on the ubiquitin-proteasome system. Moreover, Fcnb inhibition downregulated the suppressive function of PMN-MDSCs. ...
LncRNA AK036396 knockdown attenuated Fcnb protein stability in a manner dependent on the ubiquitin-proteasome system. Moreover, Fc …
Ficolin A knockout alleviates sepsis-induced severe lung injury in mice by restoring gut Akkermansia to inhibit S100A4/STAT3 pathway.
Wu X, Xuan W, Yang X, Liu W, Zhang H, Jiang G, Cao B, Jiang Y. Wu X, et al. Int Immunopharmacol. 2023 Aug;121:110548. doi: 10.1016/j.intimp.2023.110548. Epub 2023 Jun 23. Int Immunopharmacol. 2023. PMID: 37356123
This study aimed to investigate whether FcnA modulated gut microbiota to affect the progression of sepsis-induced severe ALI. Fcna(-/-) and Fcnb(-/-) C57BL/6 mice were applied to establish the ALI model by injection of LPS intraperitoneally. ...Then lung tissue wet/dry wei …
This study aimed to investigate whether FcnA modulated gut microbiota to affect the progression of sepsis-induced severe ALI. Fcna(-/-) and …
Ficolin A derived from local macrophages and neutrophils protects against lipopolysaccharide-induced acute lung injury by activating complement.
Wu X, Yao D, Bao L, Liu D, Xu X, An Y, Zhang X, Cao B. Wu X, et al. Immunol Cell Biol. 2020 Aug;98(7):595-606. doi: 10.1111/imcb.12344. Epub 2020 Jun 9. Immunol Cell Biol. 2020. PMID: 32339310
Further analyses showed that macrophages and neutrophils are the main sources of FcnA and FcnB, and T and B cells also express a small amount of FcnB. The intranasal administration of LPS induced local pulmonary inflammation with the increased recruitment of macroph …
Further analyses showed that macrophages and neutrophils are the main sources of FcnA and FcnB, and T and B cells also express a smal …
Deep-Learning Segmentation of Epicardial Adipose Tissue Using Four-Chamber Cardiac Magnetic Resonance Imaging.
Daudé P, Ancel P, Confort Gouny S, Jacquier A, Kober F, Dutour A, Bernard M, Gaborit B, Rapacchi S. Daudé P, et al. Diagnostics (Basel). 2022 Jan 6;12(1):126. doi: 10.3390/diagnostics12010126. Diagnostics (Basel). 2022. PMID: 35054297 Free PMC article.
The investigation involved 100 subjects-comprising healthy, obese, and diabetic patients-who underwent 3T cardiac cine MRI, optimized U-Net and FCN (noted FCNB) were trained on three consecutive cine frames for segmentation of central frame using dice loss. ...Networks' pe …
The investigation involved 100 subjects-comprising healthy, obese, and diabetic patients-who underwent 3T cardiac cine MRI, optimized U-Net …
Single nucleotide polymorphisms in mannan-binding lectins and ficolins in various strains of mice.
Phaneuf LR, Lillie BN, Hayes MA, Turner PV. Phaneuf LR, et al. Int J Immunogenet. 2007 Aug;34(4):259-67. doi: 10.1111/j.1744-313X.2007.00689.x. Int J Immunogenet. 2007. PMID: 17627761
Sequence comparisons identified a total of 15 structural SNPs in Mbl1 in two strains, 27 SNPs in Mbl2 in five strains, and 19 and 15 SNPs in Fcna and Fcnb, respectively, in two strains. Two non-synonymous SNPs were identified in the collagen-like domain of mouse Fcnb …
Sequence comparisons identified a total of 15 structural SNPs in Mbl1 in two strains, 27 SNPs in Mbl2 in five strains, and 19 and 15 SNPs in …
The role of nuclear factors as "Find-Me"/alarmin signals and immunostimulation in defective efferocytosis and related disorders.
Tajbakhsh A, Rezaee M, Barreto GE, Moallem SA, Henney NC, Sahebkar A. Tajbakhsh A, et al. Int Immunopharmacol. 2020 Mar;80:106134. doi: 10.1016/j.intimp.2019.106134. Epub 2020 Jan 10. Int Immunopharmacol. 2020. PMID: 31931365 Review.
Previous studies have shown that these molecules also serve as targets for pharmacological agents such as necrostatins, recombinant Fcnb, anti-histone, neutralizing antibodies, calbiochem, aminophylline, activated protein C, CD24IgG recombinant fission protein, and recombi …
Previous studies have shown that these molecules also serve as targets for pharmacological agents such as necrostatins, recombinant Fcnb …
A new algorithm for reducing the workload of experts in performing systematic reviews.
Matwin S, Kouznetsov A, Inkpen D, Frunza O, O'Blenis P. Matwin S, et al. J Am Med Inform Assoc. 2010 Jul-Aug;17(4):446-53. doi: 10.1136/jamia.2010.004325. J Am Med Inform Assoc. 2010. PMID: 20595313 Free PMC article.
OBJECTIVE: To determine whether a factorized version of the complement naive Bayes (FCNB) classifier can reduce the time spent by experts reviewing journal articles for inclusion in systematic reviews of drug class efficacy for disease treatment. ...RESULTS: The minimum wo …
OBJECTIVE: To determine whether a factorized version of the complement naive Bayes (FCNB) classifier can reduce the time spent by exp …
21 results