Fedorov O - Search Results

1

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE. D'Ascenzio M, et al. Among authors: fedorov o. Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27. Angew Chem Int Ed Engl. 2019. PMID: 30589164 Free PMC article.

2

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.

Bullock AN, Debreczeni JE, Fedorov OY, Nelson A, Marsden BD, Knapp S. Bullock AN, et al. J Med Chem. 2005 Dec 1;48(24):7604-14. doi: 10.1021/jm0504858. J Med Chem. 2005. PMID: 16302800

3

Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.

Eswaran J, Lee WH, Debreczeni JE, Filippakopoulos P, Turnbull A, Fedorov O, Deacon SW, Peterson JR, Knapp S. Eswaran J, et al. Among authors: fedorov o. Structure. 2007 Feb;15(2):201-13. doi: 10.1016/j.str.2007.01.001. Structure. 2007. PMID: 17292838 Free PMC article.

4

Insights for the development of specific kinase inhibitors by targeted structural genomics.

Fedorov O, Sundström M, Marsden B, Knapp S. Fedorov O, et al. Drug Discov Today. 2007 May;12(9-10):365-72. doi: 10.1016/j.drudis.2007.03.006. Epub 2007 Mar 29. Drug Discov Today. 2007. PMID: 17467572 Review.

5

Structural and functional characterization of the human protein kinase ASK1.

Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Müller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, Knapp S. Bunkoczi G, et al. Among authors: fedorov o. Structure. 2007 Oct;15(10):1215-26. doi: 10.1016/j.str.2007.08.011. Structure. 2007. PMID: 17937911 Free PMC article.

6

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S. Fedorov O, et al. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. doi: 10.1073/pnas.0708800104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077363 Free PMC article.

7

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.

Bullock AN, Das S, Debreczeni JE, Rellos P, Fedorov O, Niesen FH, Guo K, Papagrigoriou E, Amos AL, Cho S, Turk BE, Ghosh G, Knapp S. Bullock AN, et al. Among authors: fedorov o. Structure. 2009 Mar 11;17(3):352-62. doi: 10.1016/j.str.2008.12.023. Structure. 2009. PMID: 19278650 Free PMC article.

8

Structure of dystrophia myotonica protein kinase.

Elkins JM, Amos A, Niesen FH, Pike AC, Fedorov O, Knapp S. Elkins JM, et al. Among authors: fedorov o. Protein Sci. 2009 Apr;18(4):782-91. doi: 10.1002/pro.82. Protein Sci. 2009. PMID: 19309729 Free PMC article.

9

The (un)targeted cancer kinome.

Fedorov O, Müller S, Knapp S. Fedorov O, et al. Nat Chem Biol. 2010 Mar;6(3):166-169. doi: 10.1038/nchembio.297. Nat Chem Biol. 2010. PMID: 20154661 No abstract available.

10

Structural comparison of human mammalian ste20-like kinases.

Record CJ, Chaikuad A, Rellos P, Das S, Pike AC, Fedorov O, Marsden BD, Knapp S, Lee WH. Record CJ, et al. Among authors: fedorov o. PLoS One. 2010 Aug 6;5(8):e11905. doi: 10.1371/journal.pone.0011905. PLoS One. 2010. PMID: 20730082 Free PMC article.

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