Fessner WD - Search Results

1

Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes.

Roldán R, Hernandez K, Joglar J, Bujons J, Parella T, Sánchez-Moreno I, Hélaine V, Lemaire M, Guérard-Hélaine C, Fessner WD, Clapés P. Roldán R, et al. Among authors: fessner wd. ACS Catal. 2018 Sep 7;8(9):8804-8809. doi: 10.1021/acscatal.8b02486. Epub 2018 Aug 8. ACS Catal. 2018. PMID: 30221031 Free PMC article.

2

Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate Aldolase.

Roldán R, Sanchez-Moreno I, Scheidt T, Hélaine V, Lemaire M, Parella T, Clapés P, Fessner WD, Guérard-Hélaine C. Roldán R, et al. Among authors: fessner wd. Chemistry. 2017 Apr 11;23(21):5005-5009. doi: 10.1002/chem.201701020. Epub 2017 Mar 29. Chemistry. 2017. PMID: 28266745

3

Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes.

Roldán R, Hernández K, Joglar J, Bujons J, Parella T, Fessner WD, Clapés P. Roldán R, et al. Among authors: fessner wd. Adv Synth Catal. 2019 Jun 6;361(11):2673-2687. doi: 10.1002/adsc.201801530. Epub 2019 Feb 15. Adv Synth Catal. 2019. PMID: 31680790 Free PMC article.

4

Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products.

Junker S, Roldan R, Joosten HJ, Clapés P, Fessner WD. Junker S, et al. Among authors: fessner wd. Angew Chem Int Ed Engl. 2018 Aug 6;57(32):10153-10157. doi: 10.1002/anie.201804831. Epub 2018 Jul 4. Angew Chem Int Ed Engl. 2018. PMID: 29882622 Free PMC article.

5

Biocatalytic synthesis of hydroxylated natural products using aldolases and related enzymes.

Fessner WD, Helaine V. Fessner WD, et al. Curr Opin Biotechnol. 2001 Dec;12(6):574-86. doi: 10.1016/s0958-1669(01)00265-8. Curr Opin Biotechnol. 2001. PMID: 11849940 Review.

6

A pH-based high-throughput assay for transketolase: fingerprinting of substrate tolerance and quantitative kinetics.

Yi D, Devamani T, Abdoul-Zabar J, Charmantray F, Helaine V, Hecquet L, Fessner WD. Yi D, et al. Among authors: fessner wd. Chembiochem. 2012 Oct 15;13(15):2290-300. doi: 10.1002/cbic.201200364. Epub 2012 Sep 24. Chembiochem. 2012. PMID: 23001740

7

Recent progress in stereoselective synthesis with aldolases.

Clapés P, Fessner WD, Sprenger GA, Samland AK. Clapés P, et al. Among authors: fessner wd. Curr Opin Chem Biol. 2010 Apr;14(2):154-67. doi: 10.1016/j.cbpa.2009.11.029. Epub 2010 Jan 12. Curr Opin Chem Biol. 2010. PMID: 20071212 Review.

8

Fluorogenic stereochemical probes for transaldolases.

González-García E, Helaine V, Klein G, Schuermann M, Sprenger GA, Fessner WD, Reymond JL. González-García E, et al. Among authors: fessner wd. Chemistry. 2003 Feb 17;9(4):893-9. doi: 10.1002/chem.200390110. Chemistry. 2003. PMID: 12584704

9

A thermostable transketolase evolved for aliphatic aldehyde acceptors.

Yi D, Saravanan T, Devamani T, Charmantray F, Hecquet L, Fessner WD. Yi D, et al. Among authors: fessner wd. Chem Commun (Camb). 2015 Jan 11;51(3):480-3. doi: 10.1039/c4cc08436e. Epub 2014 Nov 21. Chem Commun (Camb). 2015. PMID: 25415647

10

Broadening deoxysugar glycodiversity: natural and engineered transaldolases unlock a complementary substrate space.

Rale M, Schneider S, Sprenger GA, Samland AK, Fessner WD. Rale M, et al. Among authors: fessner wd. Chemistry. 2011 Feb 25;17(9):2623-32. doi: 10.1002/chem.201002942. Epub 2011 Feb 2. Chemistry. 2011. PMID: 21290439

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