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Application of the SARS-CoV-2-S1 ACE-2 receptor interaction as the basis of the fully automated assay to detect neutralizing SARS-CoV-2-S1 antibodies in blood samples.
Filchtinski D, Sundberg M, Berthold H, Steller L, Kayser J, Holz S, Hinze M, Braeutigam O, Schulte-Pelkum J, Fiedler R. Filchtinski D, et al. J Immunol Methods. 2022 May;504:113258. doi: 10.1016/j.jim.2022.113258. Epub 2022 Mar 15. J Immunol Methods. 2022. PMID: 35304119 Free PMC article.
Elucidating the mode of action of a typical Ras state 1(T) inhibitor.
Rosnizeck IC, Filchtinski D, Lopes RP, Kieninger B, Herrmann C, Kalbitzer HR, Spoerner M. Rosnizeck IC, et al. Among authors: filchtinski d. Biochemistry. 2014 Jun 24;53(24):3867-78. doi: 10.1021/bi401689w. Biochemistry. 2014. PMID: 24866928
Improved binding of raf to Ras.GDP is correlated with biological activity.
Kiel C, Filchtinski D, Spoerner M, Schreiber G, Kalbitzer HR, Herrmann C. Kiel C, et al. Among authors: filchtinski d. J Biol Chem. 2009 Nov 13;284(46):31893-902. doi: 10.1074/jbc.M109.031153. Epub 2009 Sep 23. J Biol Chem. 2009. PMID: 19776012 Free PMC article.