Filippi I - Search Results

1

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

Radi M, Tintori C, Musumeci F, Brullo C, Zamperini C, Dreassi E, Fallacara AL, Vignaroli G, Crespan E, Zanoli S, Laurenzana I, Filippi I, Maga G, Schenone S, Angelucci A, Botta M. Radi M, et al. Among authors: filippi i. J Med Chem. 2013 Jul 11;56(13):5382-94. doi: 10.1021/jm400233w. Epub 2013 Jun 20. J Med Chem. 2013. PMID: 23746084

2

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

Dreassi E, Zizzari AT, Mori M, Filippi I, Belfiore A, Naldini A, Carraro F, Santucci A, Schenone S, Botta M. Dreassi E, et al. Among authors: filippi i. Eur J Med Chem. 2010 Dec;45(12):5958-64. doi: 10.1016/j.ejmech.2010.09.062. Epub 2010 Oct 8. Eur J Med Chem. 2010. PMID: 20970221

3

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

Radi M, Dreassi E, Brullo C, Crespan E, Tintori C, Bernardo V, Valoti M, Zamperini C, Daigl H, Musumeci F, Carraro F, Naldini A, Filippi I, Maga G, Schenone S, Botta M. Radi M, et al. Among authors: filippi i. J Med Chem. 2011 Apr 28;54(8):2610-26. doi: 10.1021/jm1012819. Epub 2011 Mar 28. J Med Chem. 2011. PMID: 21443205

4

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a scaffold for the synthesis of inhibitors of Bcr-Abl.

Arioli F, Borrelli S, Colombo F, Falchi F, Filippi I, Crespan E, Naldini A, Scalia G, Silvani A, Maga G, Carraro F, Botta M, Passarella D. Arioli F, et al. Among authors: filippi i. ChemMedChem. 2011 Nov 4;6(11):2009-18. doi: 10.1002/cmdc.201100304. Epub 2011 Aug 30. ChemMedChem. 2011. PMID: 21990039

5

Role of the hypoxic microenvironment in the antitumor activity of tyrosine kinase inhibitors.

Filippi I, Naldini A, Carraro F. Filippi I, et al. Curr Med Chem. 2011;18(19):2885-92. doi: 10.2174/092986711796150540. Curr Med Chem. 2011. PMID: 21651491 Review.

6

Carborane-conjugated 2-quinolinecarboxamide ligands of the translocator protein for boron neutron capture therapy.

Cappelli A, Valenti S, Mancini A, Giuliani G, Anzini M, Altieri S, Bortolussi S, Ferrari C, Clerici AM, Zonta C, Carraro F, Filippi I, Giorgi G, Donati A, Ristori S, Vomero S, Concas A, Biggio G. Cappelli A, et al. Among authors: filippi i. Bioconjug Chem. 2010 Dec 15;21(12):2213-21. doi: 10.1021/bc100195s. Epub 2010 Nov 18. Bioconjug Chem. 2010. PMID: 21087014

7

Downregulation of hypoxia-related responses by novel antitumor histone deacetylase inhibitors in MDAMB231 breast cancer cells.

Naldini A, Filippi I, Cini E, Rodriquez M, Carraro F, Taddei M. Naldini A, et al. Among authors: filippi i. Anticancer Agents Med Chem. 2012 May;12(4):407-13. doi: 10.2174/187152012800228706. Anticancer Agents Med Chem. 2012. PMID: 22043993

8

Thrombin inhibits IFN-gamma production in human peripheral blood mononuclear cells by promoting a Th2 profile.

Naldini A, Morena E, Filippi I, Pucci A, Bucci M, Cirino G, Carraro F. Naldini A, et al. Among authors: filippi i. J Interferon Cytokine Res. 2006 Nov;26(11):793-9. doi: 10.1089/jir.2006.26.793. J Interferon Cytokine Res. 2006. PMID: 17115897

9

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

Naldini A, Filippi I, Miglietta D, Moschetta M, Giavazzi R, Carraro F. Naldini A, et al. Among authors: filippi i. Eur J Cancer. 2010 Dec;46(18):3400-8. doi: 10.1016/j.ejca.2010.07.044. Epub 2010 Aug 26. Eur J Cancer. 2010. PMID: 20801015

10

Carbonic anhydrase XII expression is linked to suppression of Sonic hedgehog ligand expression in triple negative breast cancer cells.

Guerrini G, Durivault J, Filippi I, Criscuoli M, Monaci S, Pouyssegur J, Naldini A, Carraro F, Parks SK. Guerrini G, et al. Among authors: filippi i. Biochem Biophys Res Commun. 2019 Aug 20;516(2):408-413. doi: 10.1016/j.bbrc.2019.06.040. Epub 2019 Jun 18. Biochem Biophys Res Commun. 2019. PMID: 31221477

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