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339 results

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Page 1
New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.
Boxer AL, Gold M, Feldman H, Boeve BF, Dickinson SL, Fillit H, Ho C, Paul R, Pearlman R, Sutherland M, Verma A, Arneric SP, Alexander BM, Dickerson BC, Dorsey ER, Grossman M, Huey ED, Irizarry MC, Marks WJ, Masellis M, McFarland F, Niehoff D, Onyike CU, Paganoni S, Panzara MA, Rockwood K, Rohrer JD, Rosen H, Schuck RN, Soares HD, Tatton N. Boxer AL, et al. Among authors: fillit h. Alzheimers Dement. 2020 Jan;16(1):131-143. doi: 10.1016/j.jalz.2019.06.4956. Epub 2020 Jan 6. Alzheimers Dement. 2020. PMID: 31668596 Free PMC article.
The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier).
Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL. Boxer AL, et al. Among authors: fillit h. Alzheimers Dement. 2013 Mar;9(2):189-98. doi: 10.1016/j.jalz.2012.03.003. Epub 2012 Oct 10. Alzheimers Dement. 2013. PMID: 23062850 Free PMC article. Review.
Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development.
Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J. Boxer AL, et al. Among authors: fillit h. Alzheimers Dement. 2013 Mar;9(2):176-88. doi: 10.1016/j.jalz.2012.03.002. Epub 2012 Oct 5. Alzheimers Dement. 2013. PMID: 23043900 Free PMC article. Review.
Value-Generating Exploratory Trials in Neurodegenerative Dementias.
Friedman LG, McKeehan N, Hara Y, Cummings JL, Matthews DC, Zhu J, Mohs RC, Wang D, Hendrix SB, Quintana M, Schneider LS, Grundman M, Dickson SP, Feldman HH, Jaeger J, Finger EC, Ryan JM, Niehoff D, Dickinson SL, Markowitz JT, Owen M, Travaglia A, Fillit HM. Friedman LG, et al. Among authors: fillit hm. Neurology. 2021 May 18;96(20):944-954. doi: 10.1212/WNL.0000000000011774. Epub 2021 Mar 5. Neurology. 2021. PMID: 33674360 Free PMC article. Review.
Developing novel blood-based biomarkers for Alzheimer's disease.
Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, Bain LJ, Shineman DW, Weiner M, Fillit HM. Snyder HM, et al. Among authors: fillit hm. Alzheimers Dement. 2014 Jan;10(1):109-14. doi: 10.1016/j.jalz.2013.10.007. Alzheimers Dement. 2014. PMID: 24365657 Free PMC article. Review.
Recommendations to address key recruitment challenges of Alzheimer's disease clinical trials.
Langbaum JB, Zissimopoulos J, Au R, Bose N, Edgar CJ, Ehrenberg E, Fillit H, Hill CV, Hughes L, Irizarry M, Kremen S, Lakdawalla D, Lynn N, Malzbender K, Maruyama T, Massett HA, Patel D, Peneva D, Reiman EM, Romero K, Routledge C, Weiner MW, Weninger S, Aisen PS. Langbaum JB, et al. Among authors: fillit h. Alzheimers Dement. 2023 Feb;19(2):696-707. doi: 10.1002/alz.12737. Epub 2022 Aug 10. Alzheimers Dement. 2023. PMID: 35946590 Free PMC article. Review.
New directions for frontotemporal dementia drug discovery.
Trojanowski JQ, Duff K, Fillit H, Koroshetz W, Kuret J, Murphy D, Refolo L; Frontotemporal Dementia (FTD) Working Group on FTD Drug Discovery. Trojanowski JQ, et al. Among authors: fillit h. Alzheimers Dement. 2008 Mar;4(2):89-93. doi: 10.1016/j.jalz.2007.06.001. Epub 2007 Sep 10. Alzheimers Dement. 2008. PMID: 18631953 Free PMC article.
Dependence as a unifying construct in defining Alzheimer's disease severity.
McLaughlin T, Feldman H, Fillit H, Sano M, Schmitt F, Aisen P, Leibman C, Mucha L, Ryan JM, Sullivan SD, Spackman DE, Neumann PJ, Cohen J, Stern Y. McLaughlin T, et al. Among authors: fillit h. Alzheimers Dement. 2010 Nov;6(6):482-93. doi: 10.1016/j.jalz.2009.09.004. Alzheimers Dement. 2010. PMID: 21044778 Free PMC article. Review.
Alzheimer's Disease-Related Dementias Summit 2016: National research priorities.
Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, Marder KS, Moy CS, Phelps CH, Scott PA, Seeley WW, Sieber BA, Silverberg NB, Sutherland ML, Taylor A, Torborg CL, Waddy SP, Gubitz AK, Holtzman DM. Corriveau RA, et al. Among authors: fillit h. Neurology. 2017 Dec 5;89(23):2381-2391. doi: 10.1212/WNL.0000000000004717. Epub 2017 Nov 8. Neurology. 2017. PMID: 29117955 Free PMC article. Review.
339 results