Fletcher JA - Search Results

1

BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor.

Tsai HJ, Jiaang WT, Shih NY, Fletcher JA, Lin MJ, Yang MY, Chen CT, Hsu TJ, Wu CC, Lin HY, Chen LT. Tsai HJ, et al. Among authors: fletcher ja. Cancer Sci. 2018 Nov;109(11):3591-3601. doi: 10.1111/cas.13773. Epub 2018 Sep 21. Cancer Sci. 2018. PMID: 30142229 Free PMC article.

2

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.

Lux ML, Rubin BP, Biase TL, Chen CJ, Maclure T, Demetri G, Xiao S, Singer S, Fletcher CD, Fletcher JA. Lux ML, et al. Among authors: fletcher ja, fletcher cd. Am J Pathol. 2000 Mar;156(3):791-5. doi: 10.1016/S0002-9440(10)64946-2. Am J Pathol. 2000. PMID: 10702394 Free PMC article.

3

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

Rubin BP, Singer S, Tsao C, Duensing A, Lux ML, Ruiz R, Hibbard MK, Chen CJ, Xiao S, Tuveson DA, Demetri GD, Fletcher CD, Fletcher JA. Rubin BP, et al. Among authors: fletcher ja, fletcher cd. Cancer Res. 2001 Nov 15;61(22):8118-21. Cancer Res. 2001. PMID: 11719439

4

Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations.

Heinrich MC, Rubin BP, Longley BJ, Fletcher JA. Heinrich MC, et al. Among authors: fletcher ja. Hum Pathol. 2002 May;33(5):484-95. doi: 10.1053/hupa.2002.124124. Hum Pathol. 2002. PMID: 12094373 Review.

5

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.

Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, Heinrich MC, Tuveson DA, Singer S, Janicek M, Fletcher JA, Silverman SG, Silberman SL, Capdeville R, Kiese B, Peng B, Dimitrijevic S, Druker BJ, Corless C, Fletcher CD, Joensuu H. Demetri GD, et al. Among authors: fletcher ja, fletcher cd. N Engl J Med. 2002 Aug 15;347(7):472-80. doi: 10.1056/NEJMoa020461. N Engl J Med. 2002. PMID: 12181401 Free article. Clinical Trial.

6

PDGFRA activating mutations in gastrointestinal stromal tumors.

Heinrich MC, Corless CL, Duensing A, McGreevey L, Chen CJ, Joseph N, Singer S, Griffith DJ, Haley A, Town A, Demetri GD, Fletcher CD, Fletcher JA. Heinrich MC, et al. Among authors: fletcher ja, fletcher cd. Science. 2003 Jan 31;299(5607):708-10. doi: 10.1126/science.1079666. Epub 2003 Jan 9. Science. 2003. PMID: 12522257

7

Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).

Duensing A, Medeiros F, McConarty B, Joseph NE, Panigrahy D, Singer S, Fletcher CD, Demetri GD, Fletcher JA. Duensing A, et al. Among authors: fletcher ja, fletcher cd. Oncogene. 2004 May 13;23(22):3999-4006. doi: 10.1038/sj.onc.1207525. Oncogene. 2004. PMID: 15007386

8

Biology of gastrointestinal stromal tumors: KIT mutations and beyond.

Duensing A, Heinrich MC, Fletcher CD, Fletcher JA. Duensing A, et al. Among authors: fletcher ja, fletcher cd. Cancer Invest. 2004;22(1):106-16. doi: 10.1081/cnv-120027585. Cancer Invest. 2004. PMID: 15069768 Review.

9

KIT-negative gastrointestinal stromal tumors: proof of concept and therapeutic implications.

Medeiros F, Corless CL, Duensing A, Hornick JL, Oliveira AM, Heinrich MC, Fletcher JA, Fletcher CD. Medeiros F, et al. Among authors: fletcher ja, fletcher cd. Am J Surg Pathol. 2004 Jul;28(7):889-94. doi: 10.1097/00000478-200407000-00007. Am J Surg Pathol. 2004. PMID: 15223958

10

Protein Kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs).

Duensing A, Joseph NE, Medeiros F, Smith F, Hornick JL, Heinrich MC, Corless CL, Demetri GD, Fletcher CD, Fletcher JA. Duensing A, et al. Among authors: fletcher ja, fletcher cd. Cancer Res. 2004 Aug 1;64(15):5127-31. doi: 10.1158/0008-5472.CAN-04-0559. Cancer Res. 2004. PMID: 15289315

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