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Subversion of the Bcl-2 life/death switch in cancer development and therapy.
Adams JM, Huang DC, Strasser A, Willis S, Chen L, Wei A, van Delft M, Fletcher JI, Puthalakath H, Kuroda J, Michalak EM, Kelly PN, Bouillet P, Villunger A, O'Reilly L, Bath ML, Smith DP, Egle A, Harris AW, Hinds M, Colman P, Cory S. Adams JM, et al. Among authors: fletcher ji. Cold Spring Harb Symp Quant Biol. 2005;70:469-77. doi: 10.1101/sqb.2005.70.009. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869785
BH3-only proteins: orchestrating cell death.
Fletcher JI, Huang DC. Fletcher JI, et al. Cell Death Differ. 2006 Aug;13(8):1268-71. doi: 10.1038/sj.cdd.4401995. Epub 2006 Jun 9. Cell Death Differ. 2006. PMID: 16763613 No abstract available.
Programmed anuclear cell death delimits platelet life span.
Mason KD, Carpinelli MR, Fletcher JI, Collinge JE, Hilton AA, Ellis S, Kelly PN, Ekert PG, Metcalf D, Roberts AW, Huang DC, Kile BT. Mason KD, et al. Among authors: fletcher ji. Cell. 2007 Mar 23;128(6):1173-86. doi: 10.1016/j.cell.2007.01.037. Cell. 2007. PMID: 17382885 Free article.
Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.
Fletcher JI, Meusburger S, Hawkins CJ, Riglar DT, Lee EF, Fairlie WD, Huang DC, Adams JM. Fletcher JI, et al. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18081-7. doi: 10.1073/pnas.0808691105. Epub 2008 Nov 3. Proc Natl Acad Sci U S A. 2008. PMID: 18981409 Free PMC article.
Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM. Kvansakul M, et al. Among authors: fletcher ji. PLoS Pathog. 2010 Dec 23;6(12):e1001236. doi: 10.1371/journal.ppat.1001236. PLoS Pathog. 2010. PMID: 21203485 Free PMC article.
61 results