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Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.
Thomas SE, Collins P, James RH, Mendes V, Charoensutthivarakul S, Radoux C, Abell C, Coyne AG, Floto RA, von Delft F, Blundell TL. Thomas SE, et al. Among authors: floto ra. Philos Trans A Math Phys Eng Sci. 2019 Jun 17;377(2147):20180422. doi: 10.1098/rsta.2018.0422. Philos Trans A Math Phys Eng Sci. 2019. PMID: 31030650 Free PMC article.
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.
Renna M, Schaffner C, Brown K, Shang S, Tamayo MH, Hegyi K, Grimsey NJ, Cusens D, Coulter S, Cooper J, Bowden AR, Newton SM, Kampmann B, Helm J, Jones A, Haworth CS, Basaraba RJ, DeGroote MA, Ordway DJ, Rubinsztein DC, Floto RA. Renna M, et al. Among authors: floto ra. J Clin Invest. 2011 Sep;121(9):3554-63. doi: 10.1172/JCI46095. Epub 2011 Aug 1. J Clin Invest. 2011. PMID: 21804191 Free PMC article.
US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis: executive summary.
Floto RA, Olivier KN, Saiman L, Daley CL, Herrmann JL, Nick JA, Noone PG, Bilton D, Corris P, Gibson RL, Hempstead SE, Koetz K, Sabadosa KA, Sermet-Gaudelus I, Smyth AR, van Ingen J, Wallace RJ, Winthrop KL, Marshall BC, Haworth CS. Floto RA, et al. Thorax. 2016 Jan;71(1):88-90. doi: 10.1136/thoraxjnl-2015-207983. Thorax. 2016. PMID: 26678435 Free PMC article.
British Thoracic Society Guideline for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD).
Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA. Haworth CS, et al. Among authors: floto ra. BMJ Open Respir Res. 2017 Oct 19;4(1):e000242. doi: 10.1136/bmjresp-2017-000242. eCollection 2017. BMJ Open Respir Res. 2017. PMID: 29449949 Free PMC article. Review.
Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson's disease.
Wijeyekoon RS, Kronenberg-Versteeg D, Scott KM, Hayat S, Kuan WL, Evans JR, Breen DP, Cummins G, Jones JL, Clatworthy MR, Floto RA, Barker RA, Williams-Gray CH. Wijeyekoon RS, et al. Among authors: floto ra. Brain Behav Immun. 2020 Jul;87:473-488. doi: 10.1016/j.bbi.2020.01.018. Epub 2020 Jan 30. Brain Behav Immun. 2020. PMID: 32006615 Free PMC article.
104 results