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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 2
1980 2
1981 6
1982 7
1983 7
1984 10
1985 11
1986 12
1987 11
1988 12
1989 4
1990 20
1991 17
1992 18
1993 25
1994 19
1995 32
1996 20
1997 29
1998 19
1999 25
2000 33
2001 18
2002 31
2003 19
2004 29
2005 20
2006 39
2007 34
2008 28
2009 23
2010 29
2011 25
2012 31
2013 32
2014 40
2015 34
2016 35
2017 53
2018 33
2019 35
2020 45
2021 32
2022 19
2023 25
2024 18

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985 results

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Page 1
Cancer-associated fibroblasts-derived FMO2 as a biomarker of macrophage infiltration and prognosis in epithelial ovarian cancer.
Yu S, Yang R, Xu T, Li X, Wu S, Zhang J. Yu S, et al. Gynecol Oncol. 2022 Nov;167(2):342-353. doi: 10.1016/j.ygyno.2022.09.003. Epub 2022 Sep 14. Gynecol Oncol. 2022. PMID: 36114029
Besides, FMO2 had the predictive power for worse clinical outcome of EOC patients. In the mesenchymal subtype of EOC, the FMO2-defined signature revealed that FMO2 contributed to infiltration of tumor-infiltrating lymphocytes. ...
Besides, FMO2 had the predictive power for worse clinical outcome of EOC patients. In the mesenchymal subtype of EOC, the FMO2 …
The FMO2 analysis of the ligand-receptor binding energy: the Biscarbene-Gold(I)/DNA G-Quadruplex case study.
Paciotti R, Coletti C, Marrone A, Re N. Paciotti R, et al. J Comput Aided Mol Des. 2022 Dec;36(12):851-866. doi: 10.1007/s10822-022-00484-z. Epub 2022 Nov 1. J Comput Aided Mol Des. 2022. PMID: 36318393
In this work, the ab initio fragment molecular orbital (FMO) method was applied to calculate and analyze the binding energy of two biscarbene-Au(I) derivatives, [Au(9-methylcaffein-8-ylidene)(2)](+) and [Au(1,3-dimethylbenzimidazol-2-ylidene)(2)](+), to the DNA G-Quadruplex struc …
In this work, the ab initio fragment molecular orbital (FMO) method was applied to calculate and analyze the binding energy of two biscarben …
SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin.
Tabib T, Morse C, Wang T, Chen W, Lafyatis R. Tabib T, et al. J Invest Dermatol. 2018 Apr;138(4):802-810. doi: 10.1016/j.jid.2017.09.045. Epub 2017 Dec 6. J Invest Dermatol. 2018. PMID: 29080679 Free PMC article.
Further subpopulations were defined within each of the SFRP2 and FMO1 populations and five minor fibroblast populations, each expressing discrete genes: CRABP1, COL11A1, FMO2, PRG4, or C2ORF40. Immunofluorescent staining confirmed that SFRP2 and FMO1 define cell types of d …
Further subpopulations were defined within each of the SFRP2 and FMO1 populations and five minor fibroblast populations, each expressing dis …
Discovery and identification of the prognostic significance and potential mechanism of FMO2 in breast cancer.
Wu L, Chu J, Shangguan L, Cao M, Lu F. Wu L, et al. Aging (Albany NY). 2023 Nov 13;15(21):12651-12673. doi: 10.18632/aging.205204. Epub 2023 Nov 13. Aging (Albany NY). 2023. PMID: 37963835 Free PMC article.
However, the prognostic value and potential mechanism of FMO2 in breast cancer remain unclear. METHODS: The expression of FMO2 was analyzed and the relationship between FMO2 expression level and clinical indicators in breast cancer was analyzed. Then the prog …
However, the prognostic value and potential mechanism of FMO2 in breast cancer remain unclear. METHODS: The expression of FMO2 …
The FMO2 gene of laboratory rats, as in most humans, encodes a truncated protein.
Lattard V, Longin-Sauvageon C, Krueger SK, Williams DE, Benoit E. Lattard V, et al. Biochem Biophys Res Commun. 2002 Mar 29;292(2):558-63. doi: 10.1006/bbrc.2002.6656. Biochem Biophys Res Commun. 2002. PMID: 11906197
We describe the isolation and characterization of cDNAs for FMO2 from the laboratory rat. In contrast to FMO2 in other animals, each of which contain 535 amino acid residues, analysis of the sequence of the cDNAs and of a section of the corresponding gene revealed t …
We describe the isolation and characterization of cDNAs for FMO2 from the laboratory rat. In contrast to FMO2 in other animals …
Identification and characterization of the FMO2 gene in Rattus norvegicus: a good model to study metabolic and toxicological consequences of the FMO2 polymorphism.
Hugonnard M, Benoit E, Longin-Sauvageon C, Lattard V. Hugonnard M, et al. Pharmacogenetics. 2004 Oct;14(10):647-55. doi: 10.1097/00008571-200410000-00002. Pharmacogenetics. 2004. PMID: 15454729
The major allele encodes a truncated FMO2, the minor allele a full-length FMO2. In laboratory rats we previously reported a FMO2 gene encoding a truncated FMO2 (432-AA residues). ...FMO2 was strongly expressed in lungs of homozygotes for the wil …
The major allele encodes a truncated FMO2, the minor allele a full-length FMO2. In laboratory rats we previously reported a …
Circ_MACF1 targets miR-421 to upregulate FMO2 to suppress paclitaxel resistance and malignant cellular behaviors in lung adenocarcinoma.
Qian X, Chen C, Tong S, Zhang J. Qian X, et al. Thorac Cancer. 2023 Nov;14(33):3348-3357. doi: 10.1111/1759-7714.15132. Epub 2023 Oct 10. Thorac Cancer. 2023. PMID: 37814902 Free PMC article.
Circ_MACF1 targeted miR-421 and miR-421 upregulation reverted circ_MACF1-evoked effects. FMO2 served as a downstream target of miR-421 and circ_MACF1 sponged miR-421 to elevate the expression of FMO2. MiR-421 enhanced PTX resistance and LADC progression via targetin …
Circ_MACF1 targeted miR-421 and miR-421 upregulation reverted circ_MACF1-evoked effects. FMO2 served as a downstream target of miR-42 …
An ancestral human genetic variant linked to an ancient disease: A novel association of FMO2 polymorphisms with tuberculosis (TB) in Ethiopian populations provides new insight into the differential ethno-geographic distribution of FMO2*1.
Mekonnen E, Bekele E. Mekonnen E, et al. PLoS One. 2017 Oct 5;12(10):e0184931. doi: 10.1371/journal.pone.0184931. eCollection 2017. PLoS One. 2017. PMID: 28981537 Free PMC article.
It has also been found to possess a curious loss-of-function mutation (FMO2*1/FMO2*2) that demonstrates a distinctive differentiation in expression, function and ethno-geographic distribution. ...Latent Mtb infection was determined using Quantiferon to develop relia …
It has also been found to possess a curious loss-of-function mutation (FMO2*1/FMO2*2) that demonstrates a distinctive differen …
Differences in FMO2*1 allelic frequency between Hispanics of Puerto Rican and Mexican descent.
Krueger SK, Siddens LK, Martin SR, Yu Z, Pereira CB, Cabacungan ET, Hines RN, Ardlie KG, Raucy JL, Williams DE. Krueger SK, et al. Drug Metab Dispos. 2004 Dec;32(12):1337-40. doi: 10.1124/dmd.104.001099. Epub 2004 Sep 8. Drug Metab Dispos. 2004. PMID: 15355885
A polymorphism for the phase I drug-metabolizing enzyme, flavin-containing monooxygenase isoform 2 (FMO2), encoding either truncated inactive protein, FMO2X472 (FMO2.2A), or full-length active enzyme, FMO2Q472 (FMO2.1), is known and exhibits significant inter …
A polymorphism for the phase I drug-metabolizing enzyme, flavin-containing monooxygenase isoform 2 (FMO2), encoding either truncated …
Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans.
Whetstine JR, Yueh MF, McCarver DG, Williams DE, Park CS, Kang JH, Cha YN, Dolphin CT, Shephard EA, Phillips IR, Hines RN. Whetstine JR, et al. Toxicol Appl Pharmacol. 2000 Nov 1;168(3):216-24. doi: 10.1006/taap.2000.9050. Toxicol Appl Pharmacol. 2000. PMID: 11042094
Sequence analysis, however, was consistent with the 1414C allele encoding an active FMO2 enzyme. FMO2 mRNA expression was observed in most individuals, but failed to correlate with genotype or protein expression. In summary, functional FMO2 is expressed in on …
Sequence analysis, however, was consistent with the 1414C allele encoding an active FMO2 enzyme. FMO2 mRNA expression was obse …
985 results