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2005 1
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65 results

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Page 1
Inhibition of FNDC1 suppresses gastric cancer progression by interfering with Gbetagamma-VEGFR2 complex formation.
Lu Y, Huang P, Zeng X, Liu W, Zhao R, Li J, Cao G, Hu Y, Xiao Q, Wu M, Huang W, Tang X, Liu X, Wei H. Lu Y, et al. iScience. 2023 Aug 12;26(9):107534. doi: 10.1016/j.isci.2023.107534. eCollection 2023 Sep 15. iScience. 2023. PMID: 37670789 Free PMC article.
FNDC1 over-expression or knockdown promotes or inhibits tumorigenesis and metastasis, respectively. ...Altogether, our results indicate that FNDC1 might be a promising target for clinical treatment and prognostic judgment, while FNDC1 inhibition by arsenite p
FNDC1 over-expression or knockdown promotes or inhibits tumorigenesis and metastasis, respectively. ...Altogether, our results indica
Up-regulated FNDC1 accelerates stemness and chemoradiation resistance in colorectal cancer cells.
Chen L, Liu J, Wang L, Yang X, Jiang Q, Ji F, Xu Y, Fan X, Zhou Z, Fu C. Chen L, et al. Biochem Biophys Res Commun. 2022 Apr 30;602:84-90. doi: 10.1016/j.bbrc.2022.02.038. Epub 2022 Feb 25. Biochem Biophys Res Commun. 2022. PMID: 35255438 Free article.
FNDC1 expression was consistently increased in multiple independent cohorts of CRC. ...FNDC1 overexpression accelerated CRC cell survival on 5-FU or radiation treatment both in vitro and in vivo, whereas FNDC1 inhibition sensitized CRC cells to chemoradiation
FNDC1 expression was consistently increased in multiple independent cohorts of CRC. ...FNDC1 overexpression accelerated CRC ce
[FNDC1 is highly expressed in lung adenocarcinoma and closely related with poor prognosis].
Hong H, Zhu H, Li C, Zang C, Sang H, Chen L, Wang A. Hong H, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2022 Aug 20;42(8):1182-1190. doi: 10.12122/j.issn.1673-4254.2022.08.10. Nan Fang Yi Ke Da Xue Xue Bao. 2022. PMID: 36073217 Free PMC article. Chinese.
OBJECTIVE: To explore the expression of fibronectin type domain containing 1(FNDC1) protein in lung adenocarcinoma and its prognostic significance. ...CONCLUSION: FNDC1 protein is highly expressed in patients with lung adenocarcinoma and in closely related with the …
OBJECTIVE: To explore the expression of fibronectin type domain containing 1(FNDC1) protein in lung adenocarcinoma and its prognostic …
High FNDC1 expression correlates with poor prognosis in gastric cancer.
Zhong M, Zhang Y, Yuan F, Peng Y, Wu J, Yuan J, Zhu W, Zhang Y. Zhong M, et al. Exp Ther Med. 2018 Nov;16(5):3847-3854. doi: 10.3892/etm.2018.6731. Epub 2018 Sep 12. Exp Ther Med. 2018. PMID: 30402143 Free PMC article.
The associations between FNDC1 level and various clinicopathological characteristics were assessed, and the correlation between FNDC1 expression levels and prognosis of patients with gastric cancer was analyzed using a Kaplan-Meier analysis. It was demonstrated that …
The associations between FNDC1 level and various clinicopathological characteristics were assessed, and the correlation between FN
FNDC1 Promotes the Invasiveness of Gastric Cancer via Wnt/beta-Catenin Signaling Pathway and Correlates With Peritoneal Metastasis and Prognosis.
Jiang T, Gao W, Lin S, Chen H, Du B, Liu Q, Lin X, Chen Q. Jiang T, et al. Front Oncol. 2020 Dec 17;10:590492. doi: 10.3389/fonc.2020.590492. eCollection 2020. Front Oncol. 2020. PMID: 33392086 Free PMC article.
Finally, the signaling pathways involved in the regulation of FNDC1 were explored. RESULTS: FNDC1 was highly expressed in GC and was associated with PM and poor prognosis. ...CONCLUSION: FNDC1 may be associated with the invasion of GC and PM after surgery. .. …
Finally, the signaling pathways involved in the regulation of FNDC1 were explored. RESULTS: FNDC1 was highly expressed in GC a …
Overexpression of FNDC1 in Gastric Cancer and its Prognostic Significance.
Ren J, Niu G, Wang X, Song T, Hu Z, Ke C. Ren J, et al. J Cancer. 2018 Nov 13;9(24):4586-4595. doi: 10.7150/jca.27672. eCollection 2018. J Cancer. 2018. PMID: 30588242 Free PMC article.
Objectives: The aims of this study were to compare the expression of fibronectin type III domain containing 1 (FNDC1) in gastric cancer (GC) and normal gastric tissue, to explore the prognostic significance of FNDC1 expression in patients with gastric adenocarcinoma …
Objectives: The aims of this study were to compare the expression of fibronectin type III domain containing 1 (FNDC1) in gastric canc …
FNDC1 Polymorphism (rs3003174 C > T) Increased the Incidence of Coronary Artery Aneurysm in Patients with Kawasaki Disease in a Southern Chinese Population.
Lin K, Zhang L, Wang Y, Li J, Xu Y, Che D, Mai H, Yu H, Fu L, Wei B, Jiang Z, Pi L, Gu X. Lin K, et al. J Inflamm Res. 2021 Jun 21;14:2633-2640. doi: 10.2147/JIR.S311956. eCollection 2021. J Inflamm Res. 2021. PMID: 34188513 Free PMC article.
However, there have been no reports on the relationship between FNDC1 gene and KD so far. METHODS: We enrolled 1611 controls and 1459 patients with KD, including 372 patients with coronary artery aneurysm (CAA) and 179 patients with coronary artery lesion (CAL). The relati …
However, there have been no reports on the relationship between FNDC1 gene and KD so far. METHODS: We enrolled 1611 controls and 1459 …
The role of miR-143-3p/FNDC1 axis on the progression of non-small cell lung cancer.
Ma Z, Gao Q, Xin W, Wang L, Chen Y, Su C, Gao S, Sun R. Ma Z, et al. Eur J Histochem. 2023 May 3;67(2):3577. doi: 10.4081/ejh.2023.3577. Eur J Histochem. 2023. PMID: 37132497 Free PMC article.
FNDC1 silencing also suppressed the tumorigenesis of NSCLC cells in mouse model. In conclusion, FNDC1 promotes the malignant prototypes of NSCLC cells. miR-143-3p is a negative regulator of FNDC1 in NSCLC cells, which may serve as a promising therapeutic targ
FNDC1 silencing also suppressed the tumorigenesis of NSCLC cells in mouse model. In conclusion, FNDC1 promotes the malignant p
The silencing of FNDC1 inhibits the tumorigenesis of breast cancer cells via modulation of the PI3K/Akt signaling pathway.
Yunwen C, Shanshan G, Zhifei B, Saijun C, Hua Y. Yunwen C, et al. Mol Med Rep. 2021 Jun;23(6):479. doi: 10.3892/mmr.2021.12118. Epub 2021 Apr 26. Mol Med Rep. 2021. PMID: 33899120 Free PMC article.
Although many studies have indicated that FNDC1 serves vital roles in the development of various diseases, the role of FNDC1 in the progression of breast cancer (BC) remains elusive. ...FNDC1 was highly upregulated and acted as an oncogene in BC. Therefore, t …
Although many studies have indicated that FNDC1 serves vital roles in the development of various diseases, the role of FNDC1 i …
Myofibroblast transcriptome indicates SFRP2hi fibroblast progenitors in systemic sclerosis skin.
Tabib T, Huang M, Morse N, Papazoglou A, Behera R, Jia M, Bulik M, Monier DE, Benos PV, Chen W, Domsic R, Lafyatis R. Tabib T, et al. Nat Commun. 2021 Jul 19;12(1):4384. doi: 10.1038/s41467-021-24607-6. Nat Commun. 2021. PMID: 34282151 Free PMC article.
Only a fraction of SFRP2(hi) SSc fibroblasts differentiate into myofibroblasts, as shown by expression of additional markers, SFRP4 and FNDC1. Bioinformatics analysis of the SSc fibroblast transcriptomes implicated upstream transcription factors, including FOSL2, RUNX1, ST …
Only a fraction of SFRP2(hi) SSc fibroblasts differentiate into myofibroblasts, as shown by expression of additional markers, SFRP4 and F
65 results