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Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration.
Thanki K, van Eetvelde D, Geyer A, Fraire J, Hendrix R, Van Eygen H, Putteman E, Sami H, de Souza Carvalho-Wodarz C, Franzyk H, Nielsen HM, Braeckmans K, Lehr CM, Ogris M, Foged C. Thanki K, et al. Among authors: foged c. J Control Release. 2019 Sep 28;310:82-93. doi: 10.1016/j.jconrel.2019.08.004. Epub 2019 Aug 6. J Control Release. 2019. PMID: 31398360
alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying.
Christensen D, Kirby D, Foged C, Agger EM, Andersen P, Perrie Y, Nielsen HM. Christensen D, et al. Among authors: foged c. Biochim Biophys Acta. 2008 May;1778(5):1365-73. doi: 10.1016/j.bbamem.2008.01.013. Epub 2008 Jan 26. Biochim Biophys Acta. 2008. PMID: 18261458 Free article.
In previous experiments we have shown that trehalose is able to protect a non-phospholipid-based liposomal adjuvant (designated CAF01) composed of the cationic dimethyldioctadecylammonium (DDA) and trehalose 6,6'-dibehenate (TDB) during freeze-drying [D. Christensen, C. …
In previous experiments we have shown that trehalose is able to protect a non-phospholipid-based liposomal adjuvant (designated CAF01) compo …
145 results