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MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo.
Fontan L, Yang C, Kabaleeswaran V, Volpon L, Osborne MJ, Beltran E, Garcia M, Cerchietti L, Shaknovich R, Yang SN, Fang F, Gascoyne RD, Martinez-Climent JA, Glickman JF, Borden K, Wu H, Melnick A. Fontan L, et al. Cancer Cell. 2012 Dec 11;22(6):812-24. doi: 10.1016/j.ccr.2012.11.003. Cancer Cell. 2012. PMID: 23238016 Free PMC article.
Targeting lymphomas through MALT1 inhibition.
Fontan L, Melnick A. Fontan L, et al. Oncotarget. 2012 Dec;3(12):1493-4. doi: 10.18632/oncotarget.819. Oncotarget. 2012. PMID: 23455603 Free PMC article. No abstract available.
Downregulation of FOXP1 is required during germinal center B-cell function.
Sagardoy A, Martinez-Ferrandis JI, Roa S, Bunting KL, Aznar MA, Elemento O, Shaknovich R, Fontán L, Fresquet V, Perez-Roger I, Robles EF, De Smedt L, Sagaert X, Melnick A, Martinez-Climent JA. Sagardoy A, et al. Among authors: fontan l. Blood. 2013 May 23;121(21):4311-20. doi: 10.1182/blood-2012-10-462846. Epub 2013 Apr 11. Blood. 2013. PMID: 23580662 Free PMC article.
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma.
Saba NS, Liu D, Herman SE, Underbayev C, Tian X, Behrend D, Weniger MA, Skarzynski M, Gyamfi J, Fontan L, Melnick A, Grant C, Roschewski M, Navarro A, Beà S, Pittaluga S, Dunleavy K, Wilson WH, Wiestner A. Saba NS, et al. Among authors: fontan l. Blood. 2016 Jul 7;128(1):82-92. doi: 10.1182/blood-2015-11-681460. Epub 2016 Apr 28. Blood. 2016. PMID: 27127301 Free PMC article. Clinical Trial.
How Biophysical Forces Regulate Human B Cell Lymphomas.
Apoorva F, Loiben AM, Shah SB, Purwada A, Fontan L, Goldstein R, Kirby BJ, Melnick AM, Cosgrove BD, Singh A. Apoorva F, et al. Among authors: fontan l. Cell Rep. 2018 Apr 10;23(2):499-511. doi: 10.1016/j.celrep.2018.03.069. Cell Rep. 2018. PMID: 29642007 Free PMC article.
47 results