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The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions.
Montanier C, Money VA, Pires VM, Flint JE, Pinheiro BA, Goyal A, Prates JA, Izumi A, Stålbrand H, Morland C, Cartmell A, Kolenova K, Topakas E, Dodson EJ, Bolam DN, Davies GJ, Fontes CM, Gilbert HJ. Montanier C, et al. Among authors: fontes cm. PLoS Biol. 2009 Mar 31;7(3):e71. doi: 10.1371/journal.pbio.1000071. PLoS Biol. 2009. PMID: 19338387 Free PMC article.
Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function.
Montanier C, van Bueren AL, Dumon C, Flint JE, Correia MA, Prates JA, Firbank SJ, Lewis RJ, Grondin GG, Ghinet MG, Gloster TM, Herve C, Knox JP, Talbot BG, Turkenburg JP, Kerovuo J, Brzezinski R, Fontes CM, Davies GJ, Boraston AB, Gilbert HJ. Montanier C, et al. Among authors: fontes cm. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3065-70. doi: 10.1073/pnas.0808972106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218457 Free PMC article.
The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site.
Carvalho AL, Goyal A, Prates JA, Bolam DN, Gilbert HJ, Pires VM, Ferreira LM, Planas A, Romão MJ, Fontes CM. Carvalho AL, et al. Among authors: fontes cm. J Biol Chem. 2004 Aug 13;279(33):34785-93. doi: 10.1074/jbc.M405867200. Epub 2004 Jun 10. J Biol Chem. 2004. PMID: 15192099 Free article.
Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition.
Venditto I, Luis AS, Rydahl M, Schückel J, Fernandes VO, Vidal-Melgosa S, Bule P, Goyal A, Pires VM, Dourado CG, Ferreira LM, Coutinho PM, Henrissat B, Knox JP, Baslé A, Najmudin S, Gilbert HJ, Willats WG, Fontes CM. Venditto I, et al. Among authors: fontes cm. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7136-41. doi: 10.1073/pnas.1601558113. Epub 2016 Jun 13. Proc Natl Acad Sci U S A. 2016. PMID: 27298375 Free PMC article.
215 results