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Real-time analysis of the cancer genome and fragmentome from plasma and urine cell-free DNA using nanopore sequencing.
van der Pol Y, Tantyo NA, Evander N, Hentschel AE, Wever BM, Ramaker J, Bootsma S, Fransen MF, Lenos KJ, Vermeulen L, Schneiders FL, Bahce I, Nieuwenhuijzen JA, Steenbergen RD, Pegtel DM, Moldovan N, Mouliere F. van der Pol Y, et al. Among authors: fransen mf. EMBO Mol Med. 2023 Dec 7;15(12):e17282. doi: 10.15252/emmm.202217282. Epub 2023 Nov 9. EMBO Mol Med. 2023. PMID: 37942753 Free PMC article.
Multi-modal cell-free DNA genomic and fragmentomic patterns enhance cancer survival and recurrence analysis.
Moldovan N, van der Pol Y, van den Ende T, Boers D, Verkuijlen S, Creemers A, Ramaker J, Vu T, Bootsma S, Lenos KJ, Vermeulen L, Fransen MF, Pegtel M, Bahce I, van Laarhoven H, Mouliere F. Moldovan N, et al. Among authors: fransen mf. Cell Rep Med. 2024 Jan 16;5(1):101349. doi: 10.1016/j.xcrm.2023.101349. Epub 2023 Dec 20. Cell Rep Med. 2024. PMID: 38128532 Free PMC article.
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors.
Knopf P, Stowbur D, Hoffmann SHL, Hermann N, Maurer A, Bucher V, Poxleitner M, Tako B, Sonanini D, Krishnamachary B, Sinharay S, Fehrenbacher B, Gonzalez-Menendez I, Reckmann F, Bomze D, Flatz L, Kramer D, Schaller M, Forchhammer S, Bhujwalla ZM, Quintanilla-Martinez L, Schulze-Osthoff K, Pagel MD, Fransen MF, Röcken M, Martins AF, Pichler BJ, Ghoreschi K, Kneilling M. Knopf P, et al. Among authors: fransen mf. Mol Cancer. 2023 Dec 15;22(1):207. doi: 10.1186/s12943-023-01900-0. Mol Cancer. 2023. PMID: 38102680 Free PMC article.
A Bispecific γδ T-cell Engager Targeting EGFR Activates a Potent Vγ9Vδ2 T cell-Mediated Immune Response against EGFR-Expressing Tumors.
King LA, Toffoli EC, Veth M, Iglesias-Guimarais V, Slot MC, Amsen D, van de Ven R, Derks S, Fransen MF, Tuynman JB, Riedl T, Roovers RC, Adang AEP, Ruben JM, Parren PWHI, de Gruijl TD, van der Vliet HJ. King LA, et al. Among authors: fransen mf. Cancer Immunol Res. 2023 Sep 1;11(9):1237-1252. doi: 10.1158/2326-6066.CIR-23-0189. Cancer Immunol Res. 2023. PMID: 37368791
Local delivery of low-dose anti-CTLA-4 to the melanoma lymphatic basin leads to systemic Treg reduction and effector T cell activation.
van Pul KM, Notohardjo JCL, Fransen MF, Koster BD, Stam AGM, Chondronasiou D, Lougheed SM, Bakker J, Kandiah V, van den Tol MP, Jooss K, Vuylsteke RJCLM, van den Eertwegh AJM, de Gruijl TD. van Pul KM, et al. Among authors: fransen mf. Sci Immunol. 2022 Jul 15;7(73):eabn8097. doi: 10.1126/sciimmunol.abn8097. Epub 2022 Jul 15. Sci Immunol. 2022. PMID: 35857579 Clinical Trial.
Immunological Responses to Cancer Therapy.
Fransen MF. Fransen MF. Int J Mol Sci. 2022 Jun 23;23(13):6989. doi: 10.3390/ijms23136989. Int J Mol Sci. 2022. PMID: 35805986 Free PMC article.
Comparison of the tumor microenvironments of squamous cell carcinoma at different anatomical locations within the upper aerodigestive tract in relation to response to ICI therapy.
van Duijvenvoorde M, Derks S, Bahce I, Leemans CR, van de Ven R, Fransen MF. van Duijvenvoorde M, et al. Among authors: fransen mf. Clin Transl Immunology. 2022 Jan 10;11(1):e1363. doi: 10.1002/cti2.1363. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35035956 Free PMC article. Review.
49 results