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Enrichment of sequencing targets from the human genome by solution hybridization.
Tewhey R, Nakano M, Wang X, Pabón-Peña C, Novak B, Giuffre A, Lin E, Happe S, Roberts DN, LeProust EM, Topol EJ, Harismendy O, Frazer KA. Tewhey R, et al. Among authors: frazer ka. Genome Biol. 2009;10(10):R116. doi: 10.1186/gb-2009-10-10-r116. Epub 2009 Oct 16. Genome Biol. 2009. PMID: 19835619 Free PMC article.
The resequencing imperative.
Topol EJ, Frazer KA. Topol EJ, et al. Among authors: frazer ka. Nat Genet. 2007 Apr;39(4):439-40. doi: 10.1038/ng0407-439. Nat Genet. 2007. PMID: 17392801 No abstract available.
The genomics gold rush.
Topol EJ, Murray SS, Frazer KA. Topol EJ, et al. Among authors: frazer ka. JAMA. 2007 Jul 11;298(2):218-21. doi: 10.1001/jama.298.2.218. JAMA. 2007. PMID: 17622604 No abstract available.
Genetic determinants of phenotypic diversity in humans.
Rahim NG, Harismendy O, Topol EJ, Frazer KA. Rahim NG, et al. Among authors: frazer ka. Genome Biol. 2008 Apr 24;9(4):215. doi: 10.1186/gb-2008-9-4-215. Genome Biol. 2008. PMID: 18439327 Free PMC article.
Common vs. rare allele hypotheses for complex diseases.
Schork NJ, Murray SS, Frazer KA, Topol EJ. Schork NJ, et al. Among authors: frazer ka. Curr Opin Genet Dev. 2009 Jun;19(3):212-9. doi: 10.1016/j.gde.2009.04.010. Epub 2009 May 28. Curr Opin Genet Dev. 2009. PMID: 19481926 Free PMC article. Review.
Elucidating the role of 8q24 in colorectal cancer.
Harismendy O, Frazer KA. Harismendy O, et al. Among authors: frazer ka. Nat Genet. 2009 Aug;41(8):868-9. doi: 10.1038/ng0809-868. Nat Genet. 2009. PMID: 19639026 No abstract available.
Microdroplet-based PCR enrichment for large-scale targeted sequencing.
Tewhey R, Warner JB, Nakano M, Libby B, Medkova M, David PH, Kotsopoulos SK, Samuels ML, Hutchison JB, Larson JW, Topol EJ, Weiner MP, Harismendy O, Olson J, Link DR, Frazer KA. Tewhey R, et al. Among authors: frazer ka. Nat Biotechnol. 2009 Nov;27(11):1025-31. doi: 10.1038/nbt.1583. Epub 2009 Nov 1. Nat Biotechnol. 2009. PMID: 19881494 Free PMC article.
168 results