Freedman H - Search Results

1

Microtubules as Sub-Cellular Memristors.

Tuszynski JA, Friesen D, Freedman H, Sbitnev VI, Kim H, Santelices I, Kalra AP, Patel SD, Shankar K, Chua LO. Tuszynski JA, et al. Among authors: freedman h. Sci Rep. 2020 Feb 7;10(1):2108. doi: 10.1038/s41598-020-58820-y. Sci Rep. 2020. PMID: 32034179 Free PMC article.

2

Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions.

Santelices IB, Friesen DE, Bell C, Hough CM, Xiao J, Kalra A, Kar P, Freedman H, Rezania V, Lewis JD, Shankar K, Tuszynski JA. Santelices IB, et al. Among authors: freedman h. Sci Rep. 2017 Aug 29;7(1):9594. doi: 10.1038/s41598-017-09323-w. Sci Rep. 2017. PMID: 28851923 Free PMC article.

3

Microtubule ionic conduction and its implications for higher cognitive functions.

Craddock TJ, Tuszynski JA, Priel A, Freedman H. Craddock TJ, et al. Among authors: freedman h. J Integr Neurosci. 2010 Jun;9(2):103-22. doi: 10.1142/s0219635210002421. J Integr Neurosci. 2010. PMID: 20589950 Review.

4

Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.

Freedman H, Huzil JT, Luchko T, Ludueña RF, Tuszynski JA. Freedman H, et al. J Chem Inf Model. 2009 Feb;49(2):424-36. doi: 10.1021/ci8003336. J Chem Inf Model. 2009. PMID: 19434843

5

Model of ionic currents through microtubule nanopores and the lumen.

Freedman H, Rezania V, Priel A, Carpenter E, Noskov SY, Tuszynski JA. Freedman H, et al. Phys Rev E Stat Nonlin Soft Matter Phys. 2010 May;81(5 Pt 1):051912. doi: 10.1103/PhysRevE.81.051912. Epub 2010 May 11. Phys Rev E Stat Nonlin Soft Matter Phys. 2010. PMID: 20866266

6

Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia.

Craddock TJ, St George M, Freedman H, Barakat KH, Damaraju S, Hameroff S, Tuszynski JA. Craddock TJ, et al. Among authors: freedman h. PLoS One. 2012;7(6):e37251. doi: 10.1371/journal.pone.0037251. Epub 2012 Jun 25. PLoS One. 2012. PMID: 22761654 Free PMC article.

7

Improving the performance of the coupled reference interaction site model-hyper-netted chain (RISM-HNC)/simulation method for free energy of solvation.

Freedman H, Le L, Tuszynski JA, Truong TN. Freedman H, et al. J Phys Chem B. 2008 Feb 28;112(8):2340-8. doi: 10.1021/jp077179l. Epub 2008 Feb 6. J Phys Chem B. 2008. PMID: 18251537

8

Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing.

Chen K, Huzil JT, Freedman H, Ramachandran P, Antoniou A, Tuszynski JA, Kurgan L. Chen K, et al. Among authors: freedman h. J Mol Graph Model. 2008 Nov;27(4):497-505. doi: 10.1016/j.jmgm.2008.09.001. Epub 2008 Sep 10. J Mol Graph Model. 2008. PMID: 18951052

9

Molecular dynamics modeling of tubulin C-terminal tail interactions with the microtubule surface.

Freedman H, Luchko T, Luduena RF, Tuszynski JA. Freedman H, et al. Proteins. 2011 Oct;79(10):2968-82. doi: 10.1002/prot.23155. Epub 2011 Aug 26. Proteins. 2011. PMID: 21905119

10

Explicitly solvated ligand contribution to continuum solvation models for binding free energies: selectivity of theophylline binding to an RNA aptamer.

Freedman H, Huynh LP, Le L, Cheatham TE 3rd, Tuszynski JA, Truong TN. Freedman H, et al. J Phys Chem B. 2010 Feb 18;114(6):2227-37. doi: 10.1021/jp9059664. J Phys Chem B. 2010. PMID: 20099932

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