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DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling.
Martin PM, Stanley RE, Ross AP, Freitas AE, Moyer CE, Brumback AC, Iafrati J, Stapornwongkul KS, Dominguez S, Kivimäe S, Mulligan KA, Pirooznia M, McCombie WR, Potash JB, Zandi PP, Purcell SM, Sanders SJ, Zuo Y, Sohal VS, Cheyette BNR. Martin PM, et al. Among authors: freitas ae. Mol Psychiatry. 2018 Feb;23(2):467-475. doi: 10.1038/mp.2016.184. Epub 2016 Oct 18. Mol Psychiatry. 2018. PMID: 27752079 Free PMC article.
Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling.
Rosa PB, Bettio LEB, Neis VB, Moretti M, Kaufmann FN, Tavares MK, Werle I, Dalsenter Y, Platt N, Rosado AF, Fraga DB, Heinrich IA, Freitas AE, Leal RB, Rodrigues ALS. Rosa PB, et al. Among authors: freitas ae. Purinergic Signal. 2021 Jun;17(2):285-301. doi: 10.1007/s11302-021-09779-6. Epub 2021 Mar 13. Purinergic Signal. 2021. PMID: 33712981 Free PMC article.
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