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Associations of tissue damage induced inflammatory plasticity in masseter muscle with the resolution of chronic myalgia.
Lindquist KA, Shein SA, Hovhannisyan AH, Mecklenburg J, Zou Y, Lai Z, Tumanov AV, Akopian AN. Lindquist KA, et al. Sci Rep. 2023 Dec 12;13(1):22057. doi: 10.1038/s41598-023-49280-1. Sci Rep. 2023. PMID: 38086903 Free PMC article.
TMDM could be modeled by intramuscular inflammation or tissue damage. To model inflammation induced TMDM we injected complete Freund's adjuvant (CFA) into masseter muscle (MM). To model tissue damage induced TMDM we injected extracellular matrix degrading collagenas …
TMDM could be modeled by intramuscular inflammation or tissue damage. To model inflammation induced TMDM we injected complete Freund' …
Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain.
Xing Q, Cibelli A, Yang GL, Dohare P, Li QH, Scemes E, Guan FX, Spray DC. Xing Q, et al. Mil Med Res. 2024 Apr 29;11(1):27. doi: 10.1186/s40779-024-00525-8. Mil Med Res. 2024. PMID: 38685116 Free PMC article.
The von Frey test was used to quantify pain sensitivity in these mice following complete Freund's adjuvant (CFA) injection (7, 14, and 21 d). The qRT-PCR was employed to measure mRNA levels of Panx1, Panx2, Panx3, Cx43, Calhm1, and beta-catenin. ...
The von Frey test was used to quantify pain sensitivity in these mice following complete Freund's adjuvant (CFA) injection (7, …
Integrated analysis of microRNA and mRNA expression profiles in the rat spinal cord under inflammatory pain conditions.
Liu CC, Cheng JT, Li TY, Tan PH. Liu CC, et al. Eur J Neurosci. 2017 Dec;46(11):2713-2728. doi: 10.1111/ejn.13745. Epub 2017 Nov 6. Eur J Neurosci. 2017. PMID: 29044773
To increase the chance of identifying biologically relevant targets, we performed an integrated analysis of both miRNA and mRNA expression profiles in the rat spinal cord during complete Freund's adjuvant (CFA)-induced inflammatory pain. We generated miRNA and mRNA …
To increase the chance of identifying biologically relevant targets, we performed an integrated analysis of both miRNA and mRNA expression p …
Cdk5 contributes to inflammation-induced thermal hyperalgesia mediated by the p38 MAPK pathway in microglia.
Fang-Hu, Zhang HH, Yang BX, Huang JL, Shun JL, Kong FJ, Peng-Xu, Chen ZG, Lu JM. Fang-Hu, et al. Brain Res. 2015 Sep 4;1619:166-75. doi: 10.1016/j.brainres.2015.01.056. Epub 2015 Mar 26. Brain Res. 2015. PMID: 25819553 Free article.
In the present study, we examined thermal hyperalgesia provoked by peripheral injection of complete Freunds adjuvant (CFA) to test for Cdk5 signaling in the spinal dorsal horns of rats through the p38 mitogen-activated protein kinase (p38 MAPK) signaling pathway, which is …
In the present study, we examined thermal hyperalgesia provoked by peripheral injection of complete Freunds adjuvant (CFA) to test fo …
Immunomodulation of low dose streptozocin diabetes in mice reveals that insulitis is not obligatory for B cell destruction.
Papaccio G, Chieffi Baccari G, Esposito V. Papaccio G, et al. J Anat. 1992 Dec;181 ( Pt 3)(Pt 3):403-7. J Anat. 1992. PMID: 1304577 Free PMC article.
Twenty male C57Bl/J mice were injected with 50 microliters complete Freund's adjuvant (CFA) 1 wk before and 1 wk after induction of diabetes with 45 mg streptozocin (STZ)/kg body weight i.p. over 5 d. ...
Twenty male C57Bl/J mice were injected with 50 microliters complete Freund's adjuvant (CFA) 1 wk before and 1 wk after inducti …
Medical Assistant-Based Care Management for High-Risk Patients in Small Primary Care Practices: A Cluster Randomized Clinical Trial.
Freund T, Peters-Klimm F, Boyd CM, Mahler C, Gensichen J, Erler A, Beyer M, Gondan M, Rochon J, Gerlach FM, Szecsenyi J. Freund T, et al. Ann Intern Med. 2016 Mar 1;164(5):323-30. doi: 10.7326/M14-2403. Epub 2016 Feb 2. Ann Intern Med. 2016. PMID: 26833209 Clinical Trial.
MEASUREMENTS: All-cause hospitalizations at 12 months (primary outcome) and quality-of-life scores (12-Item Short Form Health Survey [SF-12] and EuroQol instrument [EQ-5D]). RESULTS: Included patients had an average of 4 co-occurring chronic conditions. ...Quality of life …
MEASUREMENTS: All-cause hospitalizations at 12 months (primary outcome) and quality-of-life scores (12-Item Short Form Health Survey [SF-12] …
Predictors of health-related quality of life in patients at risk for cardiovascular disease in European primary care.
Ludt S, Wensing M, Szecsenyi J, van Lieshout J, Rochon J, Freund T, Campbell SM, Ose D. Ludt S, et al. PLoS One. 2011;6(12):e29334. doi: 10.1371/journal.pone.0029334. Epub 2011 Dec 22. PLoS One. 2011. PMID: 22216250 Free PMC article.
A hierarchical multilevel analysis was performed to identify predictors of EQ-5D scores at patient and practice level. The mean EQ-5D score was 0.78 (SD 0.19). ...The EUPROPEP-score category 'organization' (r=0.02, p<0.0001) was positively related to EQ-5D …
A hierarchical multilevel analysis was performed to identify predictors of EQ-5D scores at patient and practice level. The mean EQ- …
Dietary ribonucleotides increase antigen-specific type 1 T-helper cells in the regional draining lymph nodes in young BALB/cJ mice.
Jyonouchi H, Sun S, Winship T, Kuchan MJ. Jyonouchi H, et al. Nutrition. 2003 Jan;19(1):41-6. doi: 10.1016/s0899-9007(02)00931-0. Nutrition. 2003. PMID: 12507638
METHODS: Mice were fed a ribonucleotide-free or ribonucleotide-supplemented diet and given OVA subcutaneously with incomplete Freund's adjuvant at 3 and 6 wk. Costimulatory molecule expression (CD86 and CD154), the state of naive versus effecter/memory Th cells, and …
METHODS: Mice were fed a ribonucleotide-free or ribonucleotide-supplemented diet and given OVA subcutaneously with incomplete Freund' …
The impact of perceived social support and sense of coherence on health-related quality of life in multimorbid primary care patients.
Vogel I, Miksch A, Goetz K, Ose D, Szecsenyi J, Freund T. Vogel I, et al. Chronic Illn. 2012 Dec;8(4):296-307. doi: 10.1177/1742395312445935. Epub 2012 Apr 19. Chronic Illn. 2012. PMID: 22517927
We analysed cross-sectional survey data on health-related quality of life (EQ-5D), perceived social support (FSozU-K22), sense of coherence (SOC-L9), social demographics and self reported morbidity of 103 multimorbid patients from 10 general practices in Germany. ...
We analysed cross-sectional survey data on health-related quality of life (EQ-5D), perceived social support (FSozU-K22), sense of coh …
25 results