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Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes.
Dallanoce C, Frigerio F, Martelli G, Grazioso G, Matera C, Pomè DY, Pucci L, Clementi F, Gotti C, De Amici M. Dallanoce C, et al. Among authors: frigerio f. Bioorg Med Chem. 2010 Jun 15;18(12):4498-508. doi: 10.1016/j.bmc.2010.04.065. Epub 2010 Apr 27. Bioorg Med Chem. 2010. PMID: 20478710
Design of novel alpha7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies.
Grazioso G, Pomè DY, Matera C, Frigerio F, Pucci L, Gotti C, Dallanoce C, De Amici M. Grazioso G, et al. Among authors: frigerio f. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6353-7. doi: 10.1016/j.bmcl.2009.09.073. Epub 2009 Sep 24. Bioorg Med Chem Lett. 2009. PMID: 19804970
Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors.
Dallanoce C, Magrone P, Matera C, Frigerio F, Grazioso G, De Amici M, Fucile S, Piccari V, Frydenvang K, Pucci L, Gotti C, Clementi F, De Micheli C. Dallanoce C, et al. Among authors: frigerio f. ChemMedChem. 2011 May 2;6(5):889-903. doi: 10.1002/cmdc.201000514. Epub 2011 Mar 1. ChemMedChem. 2011. PMID: 21365765
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5.
Graziani D, Caligari S, Callegari E, De Toma C, Longhi M, Frigerio F, Dilernia R, Menegon S, Pinzi L, Pirona L, Tazzari V, Valsecchi AE, Vistoli G, Rastelli G, Riva C. Graziani D, et al. Among authors: frigerio f. J Med Chem. 2019 Feb 14;62(3):1246-1273. doi: 10.1021/acs.jmedchem.8b01226. Epub 2019 Jan 28. J Med Chem. 2019. PMID: 30624919
104 results