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Page 1
CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations.
Brykczynska U, Pecho-Vrieseling E, Thiemeyer A, Klein J, Fruh I, Doll T, Manneville C, Fuchs S, Iazeolla M, Beibel M, Roma G, Naumann U, Kelley N, Oakeley EJ, Mueller M, Gomez-Mancilla B, Bühler M, Tabolacci E, Chiurazzi P, Neri G, Bouwmeester T, Di Giorgio FP, Fodor BD. Brykczynska U, et al. Among authors: fruh i. Stem Cell Reports. 2016 Dec 13;7(6):1059-1071. doi: 10.1016/j.stemcr.2016.10.004. Epub 2016 Nov 10. Stem Cell Reports. 2016. PMID: 27840045 Free PMC article.
High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome.
Kaufmann M, Schuffenhauer A, Fruh I, Klein J, Thiemeyer A, Rigo P, Gomez-Mancilla B, Heidinger-Millot V, Bouwmeester T, Schopfer U, Mueller M, Fodor BD, Cobos-Correa A. Kaufmann M, et al. Among authors: fruh i. J Biomol Screen. 2015 Oct;20(9):1101-11. doi: 10.1177/1087057115588287. Epub 2015 May 29. J Biomol Screen. 2015. PMID: 26024946
Identification of Small Molecules Which Induce Skeletal Muscle Differentiation in Embryonic Stem Cells via Activation of the Wnt and Inhibition of Smad2/3 and Sonic Hedgehog Pathways.
Lee H, Haller C, Manneville C, Doll T, Fruh I, Keller CG, Richards SM, Ibig-Rehm Y, Patoor M, Goette M, Bouchez LC, Mueller M. Lee H, et al. Among authors: fruh i. Stem Cells. 2016 Feb;34(2):299-310. doi: 10.1002/stem.2228. Epub 2015 Nov 17. Stem Cells. 2016. PMID: 26577380
CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.
Bidinosti M, Botta P, Krüttner S, Proenca CC, Stoehr N, Bernhard M, Fruh I, Mueller M, Bonenfant D, Voshol H, Carbone W, Neal SJ, McTighe SM, Roma G, Dolmetsch RE, Porter JA, Caroni P, Bouwmeester T, Lüthi A, Galimberti I. Bidinosti M, et al. Among authors: fruh i. Science. 2016 Mar 11;351(6278):1199-203. doi: 10.1126/science.aad5487. Epub 2016 Feb 4. Science. 2016. PMID: 26847545
Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo.
Russell OM, Fruh I, Rai PK, Marcellin D, Doll T, Reeve A, Germain M, Bastien J, Rygiel KA, Cerino R, Sailer AW, Lako M, Taylor RW, Mueller M, Lightowlers RN, Turnbull DM, Helliwell SB. Russell OM, et al. Among authors: fruh i. Sci Rep. 2018 Jan 29;8(1):1799. doi: 10.1038/s41598-018-20064-2. Sci Rep. 2018. PMID: 29379065 Free PMC article.
Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units.
Giorgetti E, Panesar M, Zhang Y, Joller S, Ronco M, Obrecht M, Lambert C, Accart N, Beckmann N, Doelemeyer A, Perrot L, Fruh I, Mueller M, Pierrel E, Summermatter S, Bidinosti M, Shimshek DR, Brachat S, Nash M. Giorgetti E, et al. Among authors: fruh i. Cell Rep. 2019 Nov 5;29(6):1539-1554.e7. doi: 10.1016/j.celrep.2019.10.003. Cell Rep. 2019. PMID: 31693894 Free article.
Engineering circuits of human iPSC-derived neurons and rat primary glia.
Girardin S, Ihle SJ, Menghini A, Krubner M, Tognola L, Duru J, Fruh I, Müller M, Ruff T, Vörös J. Girardin S, et al. Among authors: fruh i. Front Neurosci. 2023 May 12;17:1103437. doi: 10.3389/fnins.2023.1103437. eCollection 2023. Front Neurosci. 2023. PMID: 37250404 Free PMC article.