Frydenvang K - Search Results

1

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain.

Krintel C, Frydenvang K, Ceravalls de Rabassa A, Kaern AM, Gajhede M, Pickering DS, Kastrup JS. Krintel C, et al. Among authors: frydenvang k. FEBS J. 2014 May;281(10):2422-30. doi: 10.1111/febs.12795. Epub 2014 Apr 17. FEBS J. 2014. PMID: 24673938 Free article.

2

Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors.

Johansen TN, Greenwood JR, Frydenvang K, Madsen U, Krogsgaard-Larsen P. Johansen TN, et al. Among authors: frydenvang k. Chirality. 2003 Feb;15(2):167-79. doi: 10.1002/chir.10177. Chirality. 2003. PMID: 12520509 Review.

3

A tetrazolyl-substituted subtype-selective AMPA receptor agonist.

Vogensen SB, Frydenvang K, Greenwood JR, Postorino G, Nielsen B, Pickering DS, Ebert B, Bølcho U, Egebjerg J, Gajhede M, Kastrup JS, Johansen TN, Clausen RP, Krogsgaard-Larsen P. Vogensen SB, et al. Among authors: frydenvang k. J Med Chem. 2007 May 17;50(10):2408-14. doi: 10.1021/jm061439q. Epub 2007 Apr 25. J Med Chem. 2007. PMID: 17455929

4

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4.

Kasper C, Frydenvang K, Naur P, Gajhede M, Pickering DS, Kastrup JS. Kasper C, et al. Among authors: frydenvang k. FEBS Lett. 2008 Dec 10;582(29):4089-94. doi: 10.1016/j.febslet.2008.11.005. Epub 2008 Nov 18. FEBS Lett. 2008. PMID: 19022251 Free article.

5

Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine.

Frydenvang K, Lash LL, Naur P, Postila PA, Pickering DS, Smith CM, Gajhede M, Sasaki M, Sakai R, Pentikaïnen OT, Swanson GT, Kastrup JS. Frydenvang K, et al. J Biol Chem. 2009 May 22;284(21):14219-29. doi: 10.1074/jbc.M808547200. Epub 2009 Mar 18. J Biol Chem. 2009. PMID: 19297335 Free PMC article.

6

Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators.

Pøhlsgaard J, Frydenvang K, Madsen U, Kastrup JS. Pøhlsgaard J, et al. Among authors: frydenvang k. Neuropharmacology. 2011 Jan;60(1):135-50. doi: 10.1016/j.neuropharm.2010.08.004. Epub 2010 Aug 14. Neuropharmacology. 2011. PMID: 20713069 Review.

7

Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid.

Frydenvang K, Pickering DS, Greenwood JR, Krogsgaard-Larsen N, Brehm L, Nielsen B, Vogensen SB, Hald H, Kastrup JS, Krogsgaard-Larsen P, Clausen RP. Frydenvang K, et al. J Med Chem. 2010 Dec 9;53(23):8354-61. doi: 10.1021/jm101218a. Epub 2010 Nov 10. J Med Chem. 2010. PMID: 21067182

8

Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization.

Venskutonyte R, Butini S, Coccone SS, Gemma S, Brindisi M, Kumar V, Guarino E, Maramai S, Valenti S, Amir A, Valadés EA, Frydenvang K, Kastrup JS, Novellino E, Campiani G, Pickering DS. Venskutonyte R, et al. Among authors: frydenvang k. J Med Chem. 2011 Jul 14;54(13):4793-805. doi: 10.1021/jm2004078. Epub 2011 Jun 13. J Med Chem. 2011. PMID: 21619066

9

Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2.

Krintel C, Frydenvang K, Olsen L, Kristensen MT, de Barrios O, Naur P, Francotte P, Pirotte B, Gajhede M, Kastrup JS. Krintel C, et al. Among authors: frydenvang k. Biochem J. 2012 Jan 1;441(1):173-8. doi: 10.1042/BJ20111221. Biochem J. 2012. PMID: 21895609

10

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.

Venskutonytė R, Frydenvang K, Gajhede M, Bunch L, Pickering DS, Kastrup JS. Venskutonytė R, et al. Among authors: frydenvang k. J Struct Biol. 2011 Dec;176(3):307-14. doi: 10.1016/j.jsb.2011.08.014. Epub 2011 Sep 1. J Struct Biol. 2011. PMID: 21907808

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