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Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence.
Fuentes-Fayos AC, G-García ME, Pérez-Gómez JM, Montero-Hidalgo AJ, Martín-Colom J, Doval-Rosa C, Blanco-Acevedo C, Torres E, Toledano-Delgado Á, Sánchez-Sánchez R, Peralbo-Santaella E, Ortega-Salas RM, Jiménez-Vacas JM, Tena-Sempere M, López M, Castaño JP, Gahete MD, Solivera J, Luque RM. Fuentes-Fayos AC, et al. EBioMedicine. 2023 Apr;90:104484. doi: 10.1016/j.ebiom.2023.104484. Epub 2023 Mar 10. EBioMedicine. 2023. PMID: 36907105 Free PMC article.
Mouse models in endocrine tumors.
Gahete MD, Jimenez-Vacas JM, Alors-Perez E, Herrero-Aguayo V, Fuentes-Fayos AC, Pedraza-Arevalo S, Castaño JP, Luque RM. Gahete MD, et al. J Endocrinol. 2018 Nov 1:JOE-18-0571.R1. doi: 10.1530/JOE-18-0571. Online ahead of print. J Endocrinol. 2018. PMID: 30475226 Free article. Review.
Biguanides Exert Antitumoral Actions in Pituitary Tumor Cells Through AMPK-Dependent and -Independent Mechanisms.
Vázquez-Borrego MC, Fuentes-Fayos AC, Herrera-Martínez AD, L-López F, Ibáñez-Costa A, Moreno-Moreno P, Alhambra-Expósito MR, Barrera-Martín A, Blanco-Acevedo C, Dios E, Venegas-Moreno E, Solivera J, Gahete MD, Soto-Moreno A, Gálvez-Moreno MA, Castaño JP, Luque RM. Vázquez-Borrego MC, et al. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3501-3513. doi: 10.1210/jc.2019-00056. J Clin Endocrinol Metab. 2019. PMID: 30860580 Free article.
A New Generation Somatostatin-Dopamine Analogue Exerts Potent Antitumoral Actions on Pituitary Neuroendocrine Tumor Cells.
Vázquez-Borrego MC, L-López F, Gálvez-Moreno MA, Fuentes-Fayos AC, Venegas-Moreno E, Herrera-Martínez AD, Blanco-Acevedo C, Solivera J, Landsman T, Gahete MD, Soto-Moreno A, Culler MD, Castaño JP, Luque RM. Vázquez-Borrego MC, et al. Neuroendocrinology. 2020;110(1-2):70-82. doi: 10.1159/000500812. Epub 2019 Jul 5. Neuroendocrinology. 2020. PMID: 31272096 Free article.
Spliceosome component SF3B1 as novel prognostic biomarker and therapeutic target for prostate cancer.
Jiménez-Vacas JM, Herrero-Aguayo V, Gómez-Gómez E, León-González AJ, Sáez-Martínez P, Alors-Pérez E, Fuentes-Fayos AC, Martínez-López A, Sánchez-Sánchez R, González-Serrano T, López-Ruiz DJ, Requena-Tapia MJ, Castaño JP, Gahete MD, Luque RM. Jiménez-Vacas JM, et al. Transl Res. 2019 Oct;212:89-103. doi: 10.1016/j.trsl.2019.07.001. Epub 2019 Jul 9. Transl Res. 2019. PMID: 31344348
Splicing Machinery is Dysregulated in Pituitary Neuroendocrine Tumors and is Associated with Aggressiveness Features.
Vázquez-Borrego MC, Fuentes-Fayos AC, Venegas-Moreno E, Rivero-Cortés E, Dios E, Moreno-Moreno P, Madrazo-Atutxa A, Remón P, Solivera J, Wildemberg LE, Kasuki L, López-Fernández JM, Gadelha MR, Gálvez-Moreno MA, Soto-Moreno A, Gahete MD, Castaño JP, Luque RM. Vázquez-Borrego MC, et al. Cancers (Basel). 2019 Sep 26;11(10):1439. doi: 10.3390/cancers11101439. Cancers (Basel). 2019. PMID: 31561558 Free PMC article.
Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer.
Jiménez-Vacas JM, Herrero-Aguayo V, Montero-Hidalgo AJ, Gómez-Gómez E, Fuentes-Fayos AC, León-González AJ, Sáez-Martínez P, Alors-Pérez E, Pedraza-Arévalo S, González-Serrano T, Reyes O, Martínez-López A, Sánchez-Sánchez R, Ventura S, Yubero-Serrano EM, Requena-Tapia MJ, Castaño JP, Gahete MD, Luque RM. Jiménez-Vacas JM, et al. EBioMedicine. 2020 Jan;51:102547. doi: 10.1016/j.ebiom.2019.11.008. Epub 2020 Jan 3. EBioMedicine. 2020. PMID: 31902674 Free PMC article.
28 results