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Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.
Hirano I, Nakamura S, Yokota D, Ono T, Shigeno K, Fujisawa S, Shinjo K, Ohnishi K. Hirano I, et al. Among authors: fujisawa s. J Biol Chem. 2009 Aug 14;284(33):22155-22165. doi: 10.1074/jbc.M808182200. Epub 2009 Mar 4. J Biol Chem. 2009. PMID: 19261608 Free PMC article.
JmjC-domain containing histone demethylase 1B-mediated p15(Ink4b) suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia.
Nakamura S, Tan L, Nagata Y, Takemura T, Asahina A, Yokota D, Yagyu T, Shibata K, Fujisawa S, Ohnishi K. Nakamura S, et al. Among authors: fujisawa s. Mol Carcinog. 2013 Jan;52(1):57-69. doi: 10.1002/mc.20878. Epub 2011 Nov 15. Mol Carcinog. 2013. PMID: 22086844
Transcriptional repression of Cdc25B by IER5 inhibits the proliferation of leukemic progenitor cells through NF-YB and p300 in acute myeloid leukemia.
Nakamura S, Nagata Y, Tan L, Takemura T, Shibata K, Fujie M, Fujisawa S, Tanaka Y, Toda M, Makita R, Tsunekawa K, Yamada M, Yamaoka M, Yamashita J, Ohnishi K, Yamashita M. Nakamura S, et al. Among authors: fujisawa s. PLoS One. 2011;6(11):e28011. doi: 10.1371/journal.pone.0028011. Epub 2011 Nov 23. PLoS One. 2011. PMID: 22132193 Free PMC article.
In vitro IL-12 treatment of peripheral blood mononuclear cells from patients with leukemia or myelodysplastic syndromes: increase in cytotoxicity and reduction in WT1 gene expression.
Pan L, Ohnishi K, Zhang WJ, Yoshida H, Maksumova L, Muratkhodjaev F, Shigeno K, Nakamura S, Luo JM, Hao HL, Fujisawa S, Naito K, Shinjo K, Takeshita A, Ohno R. Pan L, et al. Among authors: fujisawa s. Leukemia. 2000 Sep;14(9):1634-41. doi: 10.1038/sj.leu.2401872. Leukemia. 2000. PMID: 10995011
749 results