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Both stimulation of GLP-1 receptors and inhibition of glycogenolysis additively contribute to a protective effect of oral miglitol against ischaemia-reperfusion injury in rabbits.
Iwasa M, Yamada Y, Kobayashi H, Yasuda S, Kawamura I, Sumi S, Shiraki T, Yamaki T, Ushikoshi H, Hattori A, Aoyama T, Nishigaki K, Takemura G, Fujiwara H, Minatoguchi S. Iwasa M, et al. Among authors: fujiwara h. Br J Pharmacol. 2011 Sep;164(1):119-31. doi: 10.1111/j.1476-5381.2011.01357.x. Br J Pharmacol. 2011. PMID: 21426318 Free PMC article.
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits.
Baba K, Minatoguchi S, Zhang C, Kariya T, Uno Y, Kawai T, Takahashi M, Takemura G, Fujiwara H. Baba K, et al. Among authors: fujiwara h. Clin Exp Pharmacol Physiol. 2005 Apr;32(4):263-8. doi: 10.1111/j.0305-1870.2005.04185.x. Clin Exp Pharmacol Physiol. 2005. PMID: 15810989
Benefits of reperfusion beyond infarct size limitation.
Takemura G, Nakagawa M, Kanamori H, Minatoguchi S, Fujiwara H. Takemura G, et al. Among authors: fujiwara h. Cardiovasc Res. 2009 Jul 15;83(2):269-76. doi: 10.1093/cvr/cvp032. Epub 2009 Jan 28. Cardiovasc Res. 2009. PMID: 19176600 Review.
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.
Yasuda S, Kobayashi H, Iwasa M, Kawamura I, Sumi S, Narentuoya B, Yamaki T, Ushikoshi H, Nishigaki K, Nagashima K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Yasuda S, et al. Among authors: fujiwara t, fujiwara h. Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1558-65. doi: 10.1152/ajpheart.00712.2008. Epub 2009 Mar 13. Am J Physiol Heart Circ Physiol. 2009. PMID: 19286954 Free article.
Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.
Minatoguchi S, Zhang Z, Bao N, Kobayashi H, Yasuda S, Iwasa M, Sumi S, Kawamura I, Yamada Y, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H. Minatoguchi S, et al. Among authors: fujiwara t, fujiwara h. J Cardiovasc Pharmacol. 2009 Jul;54(1):25-30. doi: 10.1097/FJC.0b013e3181a98b53. J Cardiovasc Pharmacol. 2009. PMID: 19487955
Postinfarct treatment with oxytocin improves cardiac function and remodeling via activating cell-survival signals and angiogenesis.
Kobayashi H, Yasuda S, Bao N, Iwasa M, Kawamura I, Yamada Y, Yamaki T, Sumi S, Ushikoshi H, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Kobayashi H, et al. Among authors: fujiwara t, fujiwara h. J Cardiovasc Pharmacol. 2009 Dec;54(6):510-9. doi: 10.1097/FJC.0b013e3181bfac02. J Cardiovasc Pharmacol. 2009. PMID: 19755919
Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.
Iwasa M, Kobayashi H, Yasuda S, Kawamura I, Sumi S, Yamada Y, Shiraki T, Yamaki T, Ushikoshi H, Aoyama T, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Iwasa M, et al. Among authors: fujiwara t, fujiwara h. J Cardiovasc Pharmacol. 2010 Jun;55(6):625-34. doi: 10.1097/FJC.0b013e3181dcd240. J Cardiovasc Pharmacol. 2010. PMID: 20351564
3,602 results