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Targeting the CB2 receptor and other endocannabinoid elements to delay disease progression in amyotrophic lateral sclerosis.
Br J Pharmacol. 2021 Mar;178(6):1373-1387. doi: 10.1111/bph.15386. Epub 2021 Feb 20.
Br J Pharmacol. 2021.
PMID: 33486755
Free article.
Review.
Inactivation of the CB2 receptor accelerated the neuropathological deterioration in TDP-43 transgenic mice, a model of amyotrophic lateral sclerosis.
Rodríguez-Cueto C, Gómez-Almería M, García Toscano L, Romero J, Hillard CJ, de Lago E, Fernández-Ruiz J.
Rodríguez-Cueto C, et al. Among authors: gomez almeria m.
Brain Pathol. 2021 Nov;31(6):e12972. doi: 10.1111/bpa.12972. Epub 2021 May 13.
Brain Pathol. 2021.
PMID: 33983653
Free PMC article.
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Tideglusib, a Non-ATP Competitive Inhibitor of GSK-3β as a Drug Candidate for the Treatment of Amyotrophic Lateral Sclerosis.
Martínez-González L, Gonzalo-Consuegra C, Gómez-Almería M, Porras G, de Lago E, Martín-Requero Á, Martínez A.
Martínez-González L, et al. Among authors: gomez almeria m.
Int J Mol Sci. 2021 Aug 20;22(16):8975. doi: 10.3390/ijms22168975.
Int J Mol Sci. 2021.
PMID: 34445680
Free PMC article.
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BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis.
Gómez-Almería M, Burgaz S, Costas-Insua C, Rodríguez-Cueto C, Santos-García I, Rodríguez-Crespo I, García C, Guzmán M, de Lago E, Fernández-Ruiz J.
Gómez-Almería M, et al.
Int J Mol Sci. 2021 Nov 20;22(22):12533. doi: 10.3390/ijms222212533.
Int J Mol Sci. 2021.
PMID: 34830414
Free PMC article.
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Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis.
Burgaz S, García C, Gonzalo-Consuegra C, Gómez-Almería M, Ruiz-Pino F, Unciti JD, Gómez-Cañas M, Alcalde J, Morales P, Jagerovic N, Rodríguez-Cueto C, de Lago E, Muñoz E, Fernández-Ruiz J.
Burgaz S, et al. Among authors: gomez almeria m.
Molecules. 2021 Dec 16;26(24):7643. doi: 10.3390/molecules26247643.
Molecules. 2021.
PMID: 34946726
Free PMC article.
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TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
Nozal V, Martínez-González L, Gomez-Almeria M, Gonzalo-Consuegra C, Santana P, Chaikuad A, Pérez-Cuevas E, Knapp S, Lietha D, Ramírez D, Petralla S, Monti B, Gil C, Martín-Requero A, Palomo V, de Lago E, Martinez A.
Nozal V, et al. Among authors: gomez almeria m.
J Med Chem. 2022 Jan 27;65(2):1585-1607. doi: 10.1021/acs.jmedchem.1c01942. Epub 2022 Jan 3.
J Med Chem. 2022.
PMID: 34978799
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