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Year Number of Results
1983 1
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2000 1
2003 1
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28 results

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Page 1
Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women.
Moretti D, Goede JS, Zeder C, Jiskra M, Chatzinakou V, Tjalsma H, Melse-Boonstra A, Brittenham G, Swinkels DW, Zimmermann MB. Moretti D, et al. Among authors: brittenham g. Blood. 2015 Oct 22;126(17):1981-9. doi: 10.1182/blood-2015-05-642223. Epub 2015 Aug 19. Blood. 2015. PMID: 26289639 Free article. Clinical Trial.
We recruited 54 nonanemic young women with plasma ferritin 20 g/L and conducted: (1) a dose-finding investigation with 40-, 60-, 80-, 160-, and 240-mg labeled Fe as [(57)Fe]-, [(58)Fe]-, or [(54)Fe]-FeSO4 given at 8:00 am fasting on 1 or on 2 consecutive days (study 1, n = …
We recruited 54 nonanemic young women with plasma ferritin 20 g/L and conducted: (1) a dose-finding investigation with 40-, 60-, 80-, …
Iron-chelating therapy for transfusional iron overload.
Brittenham GM. Brittenham GM. N Engl J Med. 2011 Jan 13;364(2):146-56. doi: 10.1056/NEJMct1004810. N Engl J Med. 2011. PMID: 21226580 Free PMC article. Review.
This examination shows an abnormally elevated blood-flow velocity in the middle cerebral artery. The hemoglobin level is 7.2 g per deciliter, the reticulocyte count is 12.5%, and the fetal hemoglobin level is 8.0%. ...
This examination shows an abnormally elevated blood-flow velocity in the middle cerebral artery. The hemoglobin level is 7.2 g per de …
Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injury.
Tsukamoto H, Lin M, Ohata M, Giulivi C, French SW, Brittenham G. Tsukamoto H, et al. Among authors: brittenham g. Am J Physiol. 1999 Dec;277(6):G1240-50. doi: 10.1152/ajpgi.1999.277.6.G1240. Am J Physiol. 1999. PMID: 10600822
NF-kappaB activation induced by lipopolysaccharide (LPS) in cultured hepatic macrophages (HM) may be abrogated by pretreatment of cells with a lipophilic iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one (L1, deferiprone), suggesting a role for iron in this molecular event [M. Lin …
NF-kappaB activation induced by lipopolysaccharide (LPS) in cultured hepatic macrophages (HM) may be abrogated by pretreatment of cells with …
Isotopic measurement of iron requirements in sub-Saharan African children.
Speich C, Brittenham GM, Cercamondi CI, Zeder C, Nkosi-Gondwe T, Phiri KS, Moretti D, Zimmermann MB. Speich C, et al. Among authors: brittenham gm. Am J Clin Nutr. 2021 Sep 1;114(3):986-996. doi: 10.1093/ajcn/nqab161. Am J Clin Nutr. 2021. PMID: 34113969 Free article.
Mean iron losses did not differ significantly between iron-deficient and iron-sufficient children and were comparable to WHO/FAO median estimates of 19 g/(d kg). In iron-sufficient children, median (95% CI) dietary iron absorption was 32 (28, 34) g/(d kg), comparabl …
Mean iron losses did not differ significantly between iron-deficient and iron-sufficient children and were comparable to WHO/FAO median esti …
How I treat anemia with red blood cell transfusion and iron.
Carson JL, Brittenham GM. Carson JL, et al. Among authors: brittenham gm. Blood. 2023 Aug 31;142(9):777-785. doi: 10.1182/blood.2022018521. Blood. 2023. PMID: 36315909
Clinical trials have demonstrated that a restrictive transfusion strategy of 7 to 8 g/dL is as safe as a liberal transfusion strategy of 9 to 10 g/dL in many clinical settings. ...
Clinical trials have demonstrated that a restrictive transfusion strategy of 7 to 8 g/dL is as safe as a liberal transfusion strategy …
Physiologically based serum ferritin thresholds for iron deficiency in women of reproductive age who are blood donors.
Addo OY, Mei Z, Hod EA, Jefferds ME, Sharma AJ, Flores-Ayala RC, Spitalnik SL, Brittenham GM. Addo OY, et al. Among authors: brittenham gm. Blood Adv. 2022 Jun 28;6(12):3661-3665. doi: 10.1182/bloodadvances.2022007066. Blood Adv. 2022. PMID: 35404995 Free PMC article.

Using restricted cubic spline regression analysis to determine thresholds for iron-deficient erythropoiesis, the thresholds identified by sTfR (serum ferritin < 25.4 g/L) and hemoglobin (serum ferritin < 25.3 g/L) did not differ significantly. The thresholds f

…
Using restricted cubic spline regression analysis to determine thresholds for iron-deficient erythropoiesis, the thresholds identified by sT …
Iron Deficiency in Chronic Pediatric Heart Failure: Overall Assessment and Outcomes in Dilated Cardiomyopathy.
Phillips L, Richmond M, Neunert C, Jin Z, Brittenham GM. Phillips L, et al. Among authors: brittenham gm. J Pediatr. 2023 Dec;263:113721. doi: 10.1016/j.jpeds.2023.113721. Epub 2023 Sep 9. J Pediatr. 2023. PMID: 37673205
After stratification by New York Heart Association classification, in advanced class IV, hemoglobin was reduced to 10.9 1.3 g/dL vs 12.7 2.0 g/dL in iron deficiency and sufficiency, respectively (P = .01), without a significant difference in LVEF. ...
After stratification by New York Heart Association classification, in advanced class IV, hemoglobin was reduced to 10.9 1.3 g/dL vs 1 …
A randomized trial of blood donor iron repletion on red cell quality for transfusion and donor cognition and well-being.
Hod EA, Brittenham GM, Bitan ZC, Feit Y, Gaelen JI, La Carpia F, Sandoval LA, Zhou AT, Soffing M, Mintz A, Schwartz J, Eng C, Scotto M, Caccappolo E, Habeck C, Stern Y, McMahon DJ, Kessler DA, Shaz BH, Francis RO, Spitalnik SL. Hod EA, et al. Among authors: brittenham gm. Blood. 2022 Dec 22;140(25):2730-2739. doi: 10.1182/blood.2022017288. Blood. 2022. PMID: 36069596 Free PMC article. Clinical Trial.
A first standard blood donation was followed by the gold-standard measure for red cell storage quality: a 51-chromium posttransfusion red cell recovery study. Donors were then randomized to intravenous iron repletion (1 g low-molecular-weight iron dextran) or placebo. A se …
A first standard blood donation was followed by the gold-standard measure for red cell storage quality: a 51-chromium posttransfusion red ce …
Hyponatraemia and hypokalaemia in adults with uncomplicated malaria in Thailand.
Thanachartwet V, Krudsood S, Tangpukdee N, Phumratanaprapin W, Silachamroon U, Leowattana W, Wilairatana P, Brittenham GM, Looareesuwan S, Neild GH. Thanachartwet V, et al. Among authors: brittenham gm. Trop Doct. 2008 Jul;38(3):155-7. doi: 10.1258/td.2007.070112. Trop Doct. 2008. PMID: 18628541 Free PMC article.
Other independent predictors for hypokalaemia were Plasmodium vivax infection, female gender; and for hyponatraemia, P. falciparum infection, male gender, concentrations of G-6-PD and serum bicarbonate....
Other independent predictors for hypokalaemia were Plasmodium vivax infection, female gender; and for hyponatraemia, P. falciparum infection …
28 results