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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 4
1994 2
1995 4
1996 3
1997 5
1998 1
1999 3
2000 4
2001 8
2002 7
2003 9
2004 12
2005 16
2006 26
2007 25
2008 31
2009 45
2010 44
2011 31
2012 55
2013 90
2014 117
2015 112
2016 151
2017 160
2018 162
2019 197
2020 221
2021 254
2022 267
2023 243
2024 116

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2,125 results

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Page 1
GATA3 functions downstream of BRCA1 to suppress EMT in breast cancer.
Bai F, Zhang LH, Liu X, Wang C, Zheng C, Sun J, Li M, Zhu WG, Pei XH. Bai F, et al. Theranostics. 2021 Jul 13;11(17):8218-8233. doi: 10.7150/thno.59280. eCollection 2021. Theranostics. 2021. PMID: 34373738 Free PMC article.
By using these mutant mice along with human BRCA1 deficient as well as proficient breast cancer tissues and cells, we investigated and compared the role of Brca1 and Gata3 loss in the activation of EMT in breast cancers. Results: We discovered that BRCA1 and …
By using these mutant mice along with human BRCA1 deficient as well as proficient breast cancer tissues and cells, we investigated an …
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
Lan T, Li H, Zhang D, Xu L, Liu H, Hao X, Yan X, Liao H, Chen X, Xie K, Li J, Liao M, Huang J, Yuan K, Zeng Y, Wu H. Lan T, et al. Mol Cancer. 2019 Dec 19;18(1):186. doi: 10.1186/s12943-019-1106-z. Mol Cancer. 2019. PMID: 31856849 Free PMC article.
KIAA1429 induced m6A methylation on the 3' UTR of GATA3 pre-mRNA, leading to the separation of the RNA-binding protein HuR and the degradation of GATA3 pre-mRNA. Strikingly, a long noncoding RNA (lncRNA) GATA3-AS, transcribed from the antisense strand of the …
KIAA1429 induced m6A methylation on the 3' UTR of GATA3 pre-mRNA, leading to the separation of the RNA-binding protein HuR and the de …
GATA3 in Breast Cancer: Tumor Suppressor or Oncogene?
Takaku M, Grimm SA, Wade PA. Takaku M, et al. Gene Expr. 2015;16(4):163-8. doi: 10.3727/105221615X14399878166113. Gene Expr. 2015. PMID: 26637396 Free PMC article. Review.
In breast cancer, GATA3 expression is highly correlated with the luminal transcriptional program. ...Here we discuss mutation of GATA3 in breast cancer and the potential mechanism(s) by which mutation may lead to a growth advantage in cancer....
In breast cancer, GATA3 expression is highly correlated with the luminal transcriptional program. ...Here we discuss mutation …
GATA3 mediates doxorubicin resistance by inhibiting CYB5R2-catalyzed iron reduction in breast cancer cells.
Zhu Z, Shen H, Xu J, Fang Z, Wo G, Ma Y, Yang K, Wang Y, Yu Q, Tang JH. Zhu Z, et al. Drug Resist Updat. 2023 Jul;69:100974. doi: 10.1016/j.drup.2023.100974. Epub 2023 May 9. Drug Resist Updat. 2023. PMID: 37230023 Free article.
Immunohistochemistry was performed for results validation. RESULTS: Doxorubicin-induced basal breast cancer cell death is dependent on iron-mediated ferroptosis. Overexpression of the luminal signature transcriptional factor GATA3 mediates doxorubicin resistance. .. …
Immunohistochemistry was performed for results validation. RESULTS: Doxorubicin-induced basal breast cancer cell death is dependent o …
The estrogen receptor/GATA3/FOXA1 transcriptional network: lessons learned from breast cancer.
Martin EM, Orlando KA, Yokobori K, Wade PA. Martin EM, et al. Curr Opin Struct Biol. 2021 Dec;71:65-70. doi: 10.1016/j.sbi.2021.05.015. Epub 2021 Jul 2. Curr Opin Struct Biol. 2021. PMID: 34225008 Free PMC article. Review.
Cellular identity and physiologic function in mammary epithelial cells and in many breast cancers flow from the action of a network of master transcriptional regulators including estrogen receptor alpha, GATA3, and FOXA1. ...The emerging details on mutation in ca …
Cellular identity and physiologic function in mammary epithelial cells and in many breast cancers flow from the action of a network o …
TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer.
Ai D, Yao J, Yang F, Huo L, Chen H, Lu W, Soto LMS, Jiang M, Raso MG, Wang S, Bell D, Liu J, Wang H, Tan D, Torres-Cabala C, Gan Q, Wu Y, Albarracin C, Hung MC, Meric-Bernstam F, Wistuba II, Prieto VG, Sahin AA, Ding Q. Ai D, et al. Mod Pathol. 2021 Apr;34(4):710-719. doi: 10.1038/s41379-020-00692-8. Epub 2020 Oct 3. Mod Pathol. 2021. PMID: 33011748 Free article.
Although GATA3 is the most widely used tumor marker at present to determine the breast origin, which has been shown to be an excellent marker for ER-positive and low-grade breast cancer, but it does not work well for TNBC with sensitivity as low as <20% in metapl …
Although GATA3 is the most widely used tumor marker at present to determine the breast origin, which has been shown to be an excellen …
GATA3 in development and cancer differentiation: cells GATA have it!
Chou J, Provot S, Werb Z. Chou J, et al. J Cell Physiol. 2010 Jan;222(1):42-9. doi: 10.1002/jcp.21943. J Cell Physiol. 2010. PMID: 19798694 Free PMC article. Review.
In the mammary gland, GATA3 is required for luminal epithelial cell differentiation and commitment, and its expression is progressively lost during luminal breast cancer progression as cancer cells acquire a stem cell-like phenotype. ...These findings demonst …
In the mammary gland, GATA3 is required for luminal epithelial cell differentiation and commitment, and its expression is progressive …
Gene of the month: GATA3.
Qiang Z, Jubber I, Lloyd K, Cumberbatch M, Griffin J. Qiang Z, et al. J Clin Pathol. 2023 Dec;76(12):793-797. doi: 10.1136/jcp-2023-209017. Epub 2023 Sep 19. J Clin Pathol. 2023. PMID: 37726118 Free article. Review.
Post-translational modifications modulate its activity. During development, GATA3 plays a key role in cell differentiation. Mutations in GATA3 are linked to breast and bladder cancer. GATA3 expression is a feature of the luminal subtype of bladder c …
Post-translational modifications modulate its activity. During development, GATA3 plays a key role in cell differentiation. Mutations …
TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma.
Yoon EC, Wang G, Parkinson B, Huo L, Peng Y, Wang J, Salisbury T, Wu Y, Chen H, Albarracin CT, Resetkova E, Middleton LP, Krishnamurthy S, Gan Q, Sun H, Huang X, Shen T, Chen W, Parwani AV, Sahin AA, Li Z, Ding Q. Yoon EC, et al. Hum Pathol. 2022 Jul;125:97-107. doi: 10.1016/j.humpath.2022.04.006. Epub 2022 Apr 9. Hum Pathol. 2022. PMID: 35413381
In the current study, we compared the newly identified breast marker TRPS1 with currently used breast markers GATA3 and SOX10 in whole-tissue sections from 315 cases of various subtypes of TNBC. ...Triple-negative apocrine carcinoma was the only subtype of TNBC with positi …
In the current study, we compared the newly identified breast marker TRPS1 with currently used breast markers GATA3 and SOX10 in whol …
[Expression of SOX10 and GATA3 in breast cancer and their significance].
Liu JL, Chen DS, Cheng ZQ, Hu JT. Liu JL, et al. Zhonghua Bing Li Xue Za Zhi. 2022 Jun 8;51(6):536-541. doi: 10.3760/cma.j.cn112151-20211025-00773. Zhonghua Bing Li Xue Za Zhi. 2022. PMID: 35673726 Chinese.
The expression of SOX10 and GATA3 in primary and metastatic breast cancer was detected, and the correlations between SOX10 and GATA3 and the molecular types and clinicopathological features of breast cancer were compared, and the distribution differenc …
The expression of SOX10 and GATA3 in primary and metastatic breast cancer was detected, and the correlations between SOX10 and …
2,125 results