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Did you mean gayat cancer (20 results)?
Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.
Tian X, Wu L, Jiang M, Zhang Z, Wu R, Miao J, Liu C, Gao S. Tian X, et al. Front Oncol. 2021 Apr 22;11:641399. doi: 10.3389/fonc.2021.641399. eCollection 2021. Front Oncol. 2021. PMID: 33968740 Free PMC article.
Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast cancer (BC), has yet to be fully addressed. This study aims to evaluate the clinical function of GLYAT in BC patients. METHODS: GLYAT exp …
Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast cancer (BC) …
Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.
Badenhorst CP, van der Sluis R, Erasmus E, van Dijk AA. Badenhorst CP, et al. Expert Opin Drug Metab Toxicol. 2013 Sep;9(9):1139-53. doi: 10.1517/17425255.2013.796929. Epub 2013 May 8. Expert Opin Drug Metab Toxicol. 2013. PMID: 23650932 Review.
AREAS COVERED: The authors review the importance of CoASH in metabolism, formation and toxicity of xenobiotic acyl-CoAs, and mechanisms for restoring levels of CoASH. They focus on GLYAT, glycine conjugation, how genetic variation in the GLYAT gene could influence g …
AREAS COVERED: The authors review the importance of CoASH in metabolism, formation and toxicity of xenobiotic acyl-CoAs, and mechanisms for …
Downregulation of Glycine N-Acyltransferase in Kidney Renal Clear Cell Carcinoma: A Bioinformatic-Based Screening.
Muñoz JP, Calaf GM. Muñoz JP, et al. Diagnostics (Basel). 2023 Nov 22;13(23):3505. doi: 10.3390/diagnostics13233505. Diagnostics (Basel). 2023. PMID: 38066746 Free PMC article.
In this context, our research focused on glycine N-acyltransferase (GLYAT), an enzyme known to play a role in various metabolic diseases and cancer. ...Additionally, we observed a hypomethylation in the GLYAT promoter region and a negative correlation between …
In this context, our research focused on glycine N-acyltransferase (GLYAT), an enzyme known to play a role in various metabolic disea …
dGLYAT modulates Gadd45-mediated JNK activation and cell invasion.
Xu M, Ren P, Tian J, Xiao L, Hu P, Chen P, Li W, Xue L. Xu M, et al. Cell Div. 2022 Aug 6;17(1):4. doi: 10.1186/s13008-022-00080-5. Cell Div. 2022. PMID: 35933447 Free PMC article.
BACKGROUND: Cell invasion is a crucial step of tumor metastasis, finding new regulators of which offers potential drug targets for cancer therapy. Aberrant GLYAT expression is associated with human cancers, yet its role in cancer remains unknown. ...CO …
BACKGROUND: Cell invasion is a crucial step of tumor metastasis, finding new regulators of which offers potential drug targets for cancer …
Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma.
Matsuo M, Terai K, Kameda N, Matsumoto A, Kurokawa Y, Funase Y, Nishikawa K, Sugaya N, Hiruta N, Kishimoto T. Matsuo M, et al. Biochem Biophys Res Commun. 2012 Apr 20;420(4):901-6. doi: 10.1016/j.bbrc.2012.03.099. Epub 2012 Mar 27. Biochem Biophys Res Commun. 2012. PMID: 22475485
GLYAT was shown to be expressed specifically in the liver and kidney, and the cellular localization of GLYAT protein was restricted to the mitochondria. Interestingly, labeling using highly affinity purified anti-GLYAT antibody revealed that GLYAT expr …
GLYAT was shown to be expressed specifically in the liver and kidney, and the cellular localization of GLYAT protein was restr …
Mongolian HCC vs. Caucasian HCC: The Metabolic Reprogramming Process in Mongolian HCC is an Interesting Difference.
Huang R, Yang K, Zhang Z, Song L, Dong K, Xie X, Hai X. Huang R, et al. Biochem Genet. 2023 Oct 31. doi: 10.1007/s10528-023-10527-1. Online ahead of print. Biochem Genet. 2023. PMID: 37907705
Racial/ethnic and region disparities in incidence and mortality are obviously in liver cancer. Mongolia has the highest reported incidence and mortality of hepatocellular carcinoma (HCC) in the world, while the incidence of HCC is relatively low in the United States, but d …
Racial/ethnic and region disparities in incidence and mortality are obviously in liver cancer. Mongolia has the highest reported inci …