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Long Non-coding RNA lnc-GNAT1-1 Suppresses Liver Cancer Progression via Modulation of Epithelial-Mesenchymal Transition.
Wang J, Wang W, Tang Q, Lu L, Luo Z, Li W, Lu Y, Pu J. Wang J, et al. Front Genet. 2020 Sep 24;11:1029. doi: 10.3389/fgene.2020.01029. eCollection 2020. Front Genet. 2020. PMID: 33193591 Free PMC article.
Quantitative real-time polymerase chain reaction was performed to measure the expression levels of lnc-GNAT1-1 in cancerous tissues from patients with liver cancer and in liver cancer cell lines. ...A nude mouse model was injected with xenografts to ev …
Quantitative real-time polymerase chain reaction was performed to measure the expression levels of lnc-GNAT1-1 in cancerous ti …
Long non-coding RNA lnc-GNAT1-1 inhibits gastric cancer cell proliferation and invasion through the Wnt/beta-catenin pathway in Helicobacter pylori infection.
Liu L, Shuai T, Li B, Zhu L, Li X. Liu L, et al. Mol Med Rep. 2018 Oct;18(4):4009-4015. doi: 10.3892/mmr.2018.9405. Epub 2018 Aug 20. Mol Med Rep. 2018. PMID: 30132541
Cells transfected with lnc-GNAT1-1 were used to initiate gastric cancer tumor xenografts to compare tumor growth in mice inoculated with untransfected cells. ...Thus, lnc-GNAT1-1 is downregulated in gastric cancer infected with H. pylori and lnc-GNA …
Cells transfected with lnc-GNAT1-1 were used to initiate gastric cancer tumor xenografts to compare tumor growth in mice inocu …
A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-kappaB-Snail circuit.
Ye C, Shen Z, Wang B, Li Y, Li T, Yang Y, Jiang K, Ye Y, Wang S. Ye C, et al. J Exp Clin Cancer Res. 2016 Dec 3;35(1):187. doi: 10.1186/s13046-016-0467-z. J Exp Clin Cancer Res. 2016. PMID: 27912775 Free PMC article.
BACKGROUND: The role of long non-coding RNAs (lncRNAs) in colorectal cancer (CRC) progression has not fully been elucidated. This study was designed to report the identification of a novel lncRNA, lnc-GNAT1-1, and its functional role in CRC progression. ...We furthe …
BACKGROUND: The role of long non-coding RNAs (lncRNAs) in colorectal cancer (CRC) progression has not fully been elucidated. This stu …
Overexpression of GalNAc-transferase GalNAc-T3 promotes pancreatic cancer cell growth.
Taniuchi K, Cerny RL, Tanouchi A, Kohno K, Kotani N, Honke K, Saibara T, Hollingsworth MA. Taniuchi K, et al. Oncogene. 2011 Dec 8;30(49):4843-54. doi: 10.1038/onc.2011.194. Epub 2011 May 30. Oncogene. 2011. PMID: 21625220 Free PMC article.
We report guanine the nucleotide-binding protein, alpha-transducing activity polypeptide-1 (GNAT1) as a possible substrate protein of GalNAc-T3. GalNAc-T3 is associated with O-glycosylation of GNAT1 and affects the subcellular distribution of GNAT1. ...Our re …
We report guanine the nucleotide-binding protein, alpha-transducing activity polypeptide-1 (GNAT1) as a possible substrate protein of …
[Expression, loss of heterozygosity, and methylation of GNAT1 gene in nasopharyngeal carcinoma].
Yi HM, Ren CP, Peng D, Zhou L, Li H, Yao KT. Yi HM, et al. Ai Zheng. 2007 Jan;26(1):9-14. Ai Zheng. 2007. PMID: 17222360 Free article. Chinese.
LOH analysis showed allele loss of GNAT1 in 3 (15%) specimens of NPC. LOH of GNAT1 was correlated to its expression level (P=0.016). ...Hypermethylation of GNAT1 may not be oncogenic mechanisms of NPC....
LOH analysis showed allele loss of GNAT1 in 3 (15%) specimens of NPC. LOH of GNAT1 was correlated to its expression level (P=0 …
Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma.
Chen J, Fu L, Zhang LY, Kwong DL, Yan L, Guan XY. Chen J, et al. Chin J Cancer. 2012 May;31(5):215-22. doi: 10.5732/cjc.011.10364. Epub 2012 Feb 24. Chin J Cancer. 2012. PMID: 22360856 Free PMC article. Review.
In many circumstances, loss of TSGs can be detected as diagnostic and prognostic markers in cancer. The short arm of chromosome 3 (3p) is a frequently deleted chromosomal region in NPC, with 3p21.1-21.2 and 3p25.2-26.1 being the most frequently deleted minimal regions. ...
In many circumstances, loss of TSGs can be detected as diagnostic and prognostic markers in cancer. The short arm of chromosome 3 (3p …
Photoreceptor nanotubes mediate the in vivo exchange of intracellular material.
Ortin-Martinez A, Yan NE, Tsai ELS, Comanita L, Gurdita A, Tachibana N, Liu ZC, Lu S, Dolati P, Pokrajac NT, El-Sehemy A, Nickerson PEB, Schuurmans C, Bremner R, Wallace VA. Ortin-Martinez A, et al. EMBO J. 2021 Nov 15;40(22):e107264. doi: 10.15252/embj.2020107264. Epub 2021 Sep 8. EMBO J. 2021. PMID: 34494680 Free PMC article.
[The Expression Status of 11 Genes, Located at the Commonly Deleted Region 3p21.3, in Non-small Cell Lung Cancer.].
Zhai Y, Li Y, Hu W, Wei M. Zhai Y, et al. Zhongguo Fei Ai Za Zhi. 2009 Aug 20;12(8):853-8. doi: 10.3779/j.issn.1009-3419.2009.08.04. Zhongguo Fei Ai Za Zhi. 2009. PMID: 20719170 Free article. Chinese.
BACKGROUND: The deletion of allele located at 3p21.3 region is found in 50%-80% of nonsmall cell lung cancer (NSCLC), suggesting that this region might harbor some tumor suppressor genes (TSGs). ...METHODS: Semi-quantitative reverse transcription-polymerase chain reaction …
BACKGROUND: The deletion of allele located at 3p21.3 region is found in 50%-80% of nonsmall cell lung cancer (NSCLC), suggesting that …
Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.
Sekido Y, Bader S, Latif F, Chen JY, Duh FM, Wei MH, Albanesi JP, Lee CC, Lerman MI, Minna JD. Sekido Y, et al. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4120-5. doi: 10.1073/pnas.93.9.4120. Proc Natl Acad Sci U S A. 1996. PMID: 8633026 Free PMC article.
We have identified two additional members of the human semaphorin family [human semaphorin A(V) and human semaphorin IV] in chromosome region 3p21.3, where several small cell lung cancer (SCLC) cell lines exhibit homozygous deletions indicative of a tumor suppressor gene. …
We have identified two additional members of the human semaphorin family [human semaphorin A(V) and human semaphorin IV] in chromosome regio …
Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG.
Wei MH, Latif F, Bader S, Kashuba V, Chen JY, Duh FM, Sekido Y, Lee CC, Geil L, Kuzmin I, Zabarovsky E, Klein G, Zbar B, Minna JD, Lerman MI. Wei MH, et al. Cancer Res. 1996 Apr 1;56(7):1487-92. Cancer Res. 1996. PMID: 8603390
The critical region on human chromosome 3p21.3 harboring a putative lung cancer tumor suppressor gene (TSG) was previously defined by allelotyping and recently refined by overlapping homozygous deletions. ...This large cosmid clone contig and high resolution maps will prov …
The critical region on human chromosome 3p21.3 harboring a putative lung cancer tumor suppressor gene (TSG) was previously defined by …
12 results