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Page 1
The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration.
Fang C, Zhong R, Qiu C, Zou BB. Fang C, et al. Front Genet. 2022 Feb 23;13:833013. doi: 10.3389/fgene.2022.833013. eCollection 2022. Front Genet. 2022. PMID: 35281820 Free PMC article.
Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, the correlation between GNG7 expression and immune infiltration as well as patient prognosis of colorectal cancer (CRC) remains …
Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, t …
Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7.
Mei J, Wang T, Zhao S, Zhang Y. Mei J, et al. J Oncol. 2021 Feb 27;2021:6610511. doi: 10.1155/2021/6610511. eCollection 2021. J Oncol. 2021. PMID: 33727922 Free PMC article.
Osthole (OST) is a plant-derived compound that can inhibit the proliferation of tumor cells and has a tumor-suppressive effect in multiple types of cancers. However, the mechanisms of OST-mediated breast cancer (BrCa) inhibition were still largely unknown. ...Beside …
Osthole (OST) is a plant-derived compound that can inhibit the proliferation of tumor cells and has a tumor-suppressive effect in multiple t …
LINC01526 Promotes Proliferation and Metastasis of Gastric Cancer by Interacting with TARBP2 to Induce GNG7 mRNA Decay.
Zhou JY, Liu JY, Tao Y, Chen C, Liu SL. Zhou JY, et al. Cancers (Basel). 2022 Oct 9;14(19):4940. doi: 10.3390/cancers14194940. Cancers (Basel). 2022. PMID: 36230863 Free PMC article.
Gastric cancer is the most common malignancy of the human digestive system. Long noncoding RNAs (lncRNAs) influence the occurrence and development of gastric cancer in multiple ways. ...In summary, LINC01526 promoted gastric cancer progression by interacting …
Gastric cancer is the most common malignancy of the human digestive system. Long noncoding RNAs (lncRNAs) influence the occurrence an …
RSPO3 induced by Helicobacter pylori extracts promotes gastric cancer stem cell properties through the GNG7/beta-catenin signaling pathway.
Rao X, Zhang Z, Pu Y, Han G, Gong H, Hu H, Ji Q, Liu N. Rao X, et al. Cancer Med. 2024 Apr;13(7):e7092. doi: 10.1002/cam4.7092. Cancer Med. 2024. PMID: 38581123 Free PMC article.
Recombinant RSPO3 protein increased the phosphorylation level of Akt and GSK-3beta, and the expression of beta-catenin in GC cells, but this regulatory effect of RSPO3 could be blocked by GNG7 knockdown. Of note, GNG7 suppression could diminish the promoting effect …
Recombinant RSPO3 protein increased the phosphorylation level of Akt and GSK-3beta, and the expression of beta-catenin in GC cells, but this …
Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer.
Ohta M, Mimori K, Fukuyoshi Y, Kita Y, Motoyama K, Yamashita K, Ishii H, Inoue H, Mori M. Ohta M, et al. Br J Cancer. 2008 Jan 29;98(2):410-7. doi: 10.1038/sj.bjc.6604124. Epub 2008 Jan 22. Br J Cancer. 2008. PMID: 18219292 Free PMC article.
We previously cloned human G protein gamma 7 (GNG7) and demonstrated that it was downregulated in gastrointestinal cancer. The significance of GNG7 expression in oesophageal cancer is unknown. ...GNG7 suppression represents a new prognostic indi …
We previously cloned human G protein gamma 7 (GNG7) and demonstrated that it was downregulated in gastrointestinal cancer. The …
Circular RNA CDR1as Inhibits the Metastasis of Gastric Cancer through Targeting miR-876-5p/GNG7 Axis.
Jiang J, Li R, Wang J, Hou J, Qian H, Xu W. Jiang J, et al. Gastroenterol Res Pract. 2021 Jun 16;2021:5583029. doi: 10.1155/2021/5583029. eCollection 2021. Gastroenterol Res Pract. 2021. PMID: 34221006 Free PMC article.
Circular RNA CDR1as has been demonstrated to participate in various cancer progressions as miRNA sponges. The exact underlying mechanisms of CDR1as on gastric cancer (GC) metastasis remain unknown. ...Bioinformatics analysis combined with dual-luciferase reporter ge …
Circular RNA CDR1as has been demonstrated to participate in various cancer progressions as miRNA sponges. The exact underlying mechan …
Identification of GNG7 as a novel biomarker and potential therapeutic target for gastric cancer via bioinformatic analysis and in vitro experiments.
Duan H, Chen B, Wang W, Luo H. Duan H, et al. Aging (Albany NY). 2023 Feb 24;15(5):1445-1474. doi: 10.18632/aging.204545. Epub 2023 Feb 24. Aging (Albany NY). 2023. PMID: 36863706 Free PMC article.
The Gene Expression Omnibus and The Cancer Genome Atlas databases were used to screen the differentially expressed genes (DEGs). ...The results of open-access database analyses suggested that GNG7 is downregulated in GC; this downregulation was associated with tumor …
The Gene Expression Omnibus and The Cancer Genome Atlas databases were used to screen the differentially expressed genes (DEGs). ...T …
GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses.
Zhang Y, Yang J, Wang X, Li X. Zhang Y, et al. Sci Rep. 2021 Oct 14;11(1):20441. doi: 10.1038/s41598-021-99544-x. Sci Rep. 2021. PMID: 34650124 Free PMC article.
The KEGG analysis on 13 selected genes showed that GNG7 and ADCY1 enriched in the Pathway in Cancer. Next, the diagnostic and prognostic value of GNG7 and ADCY1 was investigated using independent cohort of the Cancer Genome Atlas (TCGA), GSE84129 and G …
The KEGG analysis on 13 selected genes showed that GNG7 and ADCY1 enriched in the Pathway in Cancer. Next, the diagnostic and …
GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies.
Luo K, Liu M, Peng Z, Zhao H, Li G, Cai Y, Lei Y, Zhang H, Zhao Y. Luo K, et al. Front Oncol. 2025 May 27;15:1588646. doi: 10.3389/fonc.2025.1588646. eCollection 2025. Front Oncol. 2025. PMID: 40496619 Free PMC article.
G protein gamma subunit 7 (GNG7) has been implicated in the regulation of cell proliferation, apoptosis, and migration across various cancers. However, its immunological role in LUAD progression remains poorly understood. METHODS: We analyzed The Cancer Genom …
G protein gamma subunit 7 (GNG7) has been implicated in the regulation of cell proliferation, apoptosis, and migration across various …
Circ_0007099 upregulates GNG7 to function as a tumor inhibitor in gastric carcinoma by interacting with miR-425-3p.
Zhang Z, Zhou Y, Zhou N, Yin J, Kuang X. Zhang Z, et al. J Gastrointest Oncol. 2022 Aug;13(4):1626-1639. doi: 10.21037/jgo-22-684. J Gastrointest Oncol. 2022. PMID: 36092318 Free PMC article.
Furthermore, miR-425-3p directly targeted GNG7, and miR-425-3p inhibition suppressed malignant progression by reducing GNG7 expression in GC cells. Circ_0007099 sponged miR-425-3p to upregulate the level of GNG7. We also found that in vivo tumor growth was re …
Furthermore, miR-425-3p directly targeted GNG7, and miR-425-3p inhibition suppressed malignant progression by reducing GNG7 ex …
46 results